Projekter pr. år
Organisationsprofil
Organisationsprofil
Head of research group: Vladimir Zachar
Who we are?
The main theme of our research is investigation of stem cells, replacement tissues, and probiotics in order to harness their regenerative potential and synergies with the ultimate goal of developing novel therapeutic approaches.
Our research – what we do?
Our research focuses on the development of innovative interdisciplinary approaches to control the fate of stem cells and devise original clinically applicable cell- and tissue-based products. Major efforts are currently directed towards these areas:
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Use of adipose-derived stem cells in the treatment of chronic wounds, and bone and cartilage reconstruction
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Cell-based treatment of limbal stem cell deficiency
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Engineering of muscle tissue
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Probiotic Research Initiative: Application of probiotics in disease management and tissue regeneration
How does our research contribute to societal health challenges?
The group is involved in the translational research into novel regenerative therapies based on the use of probiotics, stem cells, and tissue engineering.
Who are our key collaborators?
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Prof. Hjortdal, Eye clinic, Aarhus University
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Prof. Kastrup, The heart center, Copenhagen University
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Prof. Ingersle v, Prof. Kesmodel, Fertility clinic and center for preimplantation diagnostic, Aalborg University Hospital
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Prof. Starch-Jensen, Dpt. of maxillary surgery, Aalborg University Hospital
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Assoc. Prof. Rasmussen, Dpt. of orthopedic surgery, Aalborg University Hospital
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Ass. Prof. Dolatshahi-Pirouz, DTU, Copenhagen
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Deerland Probiotics & Enzymes
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Innosurge
Fingerprint
Samarbejde i de sidste fem år
Profiler
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Sara Aghazadeh
- Det Sundhedsvidenskabelige Fakultet - Ph.d.-studerende, Videnskabelig assistent
- Institut for Medicin og Sundhedsteknologi - Ph.d.-studerende, Videnskabelig assistent
- Regenerative Medicine - Videnskabelig assistent
Person: VIP, Ekstern
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The Role of pigmentation and SERPINF1gene expression in Limbal Epithelial Stem cells’ self-renewal capability
Aghazadeh, S., Alipour, H. & Zachar, V.
01/06/2020 → 31/05/2024
Projekter: Projekt › Ph.d.-projekt
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Potency markers for Adipose-derived Stem Cells for treatment of Chronic Wounds
Ren, G., Porsborg, S. R., Fink, T., Peng, Q. & Zachar, V.
15/10/2018 → …
Projekter: Projekt › Forskning
Publikationer
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Engineering Photo-Cross-Linkable MXene-Based Hydrogels: Durable Conductive Biomaterials for Electroactive Tissues and Interfaces
Lotfi, R., Zandi, N., Pourjavadi, A., Christiansen, J. D. C., Gurevich, L., Mehrali, M., Dolatshahi-Pirouz, A., Pennisi, C. P., Tamjid, E. & Simchi, A., 12 feb. 2024, I: ACS Biomaterials Science & Engineering. 10, 2, s. 800-813 14 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Exploring the Role of Hyaluronic Acid in Reproductive Biology and Beyond: Applications in Assisted Reproduction and Tissue Engineering
Rashki Ghaleno, L., Pennisi, C. P., Shahverdi, A., Dardmeh, F., Alipour, H. & Rezazadeh Valojerdi, M., 5 apr. 2024, (E-pub ahead of print) I: Advanced biology. e2300621.Publikation: Bidrag til tidsskrift › Review (oversigtsartikel) › peer review
Åben adgang -
Seminal Oxidative Stress and Sperm DNA Fragmentation in Men from Couples with Infertility or Unexplained Recurrent Pregnancy Loss
Rasmussen, J. M. K., Dalgaard, M. I. R., Alipour, H., Dardmeh, F. & Christiansen, O. B., 31 jan. 2024, I: Journal of Clinical Medicine . 13, 3, 833.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil11 Downloads (Pure)
Forskningsdatasæt
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Data for research article titled: "Lactobacillus rhamnosus PB01 (DSM 14870) supplementation affects markers of sperm kinematic parameters in a diet-induced obesity mice model"
Dardmeh, F. (Ophavsperson), Alipour, H. (Bidrager), Gazerani, P. (Ophavsperson), Van Der Horst, G. (Bidrager), Brandsborg, E. (Ophavsperson) & Nielsen, H. I. (Ophavsperson), Figshare, 27 sep. 2017
DOI: 10.6084/m9.figshare.5446525.v1, https://figshare.com/articles/dataset/Data_for_research_article_titled_Lactobacillus_rhamnosus_PB01_DSM_14870_supplementation_affects_markers_of_sperm_kinematic_parameters_in_a_diet-induced_obesity_mice_model_/5446525/1
Datasæt
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Maintaining RNA Integrity for Transcriptomic Profiling of Ex Vivo Cultured Limbal Epithelial Stem Cells after Fluorescence-Activated Cell Sorting (FACS)
Liu, L. (Ophavsperson), Nielsen, F. M. (Ophavsperson), Porsborg, S. R. (Ophavsperson), Emmersen, J. (Ophavsperson), Fink, T. (Ophavsperson), Hjortdal, J. Ø. (Ophavsperson), Bath, C. (Ophavsperson) & Zachar, V. (Ophavsperson), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3952822.v1, https://figshare.com/collections/Maintaining_RNA_Integrity_for_Transcriptomic_Profiling_of_Ex_Vivo_Cultured_Limbal_Epithelial_Stem_Cells_after_Fluorescence-Activated_Cell_Sorting_FACS_/3952822/1
Datasæt
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Maintaining RNA Integrity for Transcriptomic Profiling of Ex Vivo Cultured Limbal Epithelial Stem Cells after Fluorescence-Activated Cell Sorting (FACS)
Liu, L. (Ophavsperson), Nielsen, F. M. (Ophavsperson), Porsborg, S. R. (Ophavsperson), Emmersen, J. (Ophavsperson), Fink, T. (Ophavsperson), Hjortdal, J. Ø. (Ophavsperson), Bath, C. (Ophavsperson) & Zachar, V. (Ophavsperson), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3952822, https://figshare.com/collections/Maintaining_RNA_Integrity_for_Transcriptomic_Profiling_of_Ex_Vivo_Cultured_Limbal_Epithelial_Stem_Cells_after_Fluorescence-Activated_Cell_Sorting_FACS_/3952822
Datasæt
Aktiviteter
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Characterization of antibodies and their influence on internalization of Chlamydia trachomatis into host cells
Pablo Pennisi (Eksaminator)
9 feb. 2024Aktivitet: Censoraktivitet og eksaminering › Intern censoraktivitet/eksaminering
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Studies for Regenerative Medicine for Vaginal Reconstructive Surgery
Pablo Pennisi (Opponent)
19 jan. 2024Aktivitet: Censoraktivitet og eksaminering › Ekstern censoraktivitet
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Investigating the role of MAPKKK, TAK1 in sensing mechanical stress
Pablo Pennisi (Opponent)
8 dec. 2023Aktivitet: Censoraktivitet og eksaminering › Ekstern censoraktivitet
Presse/medier
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Debat: Kampen om lægestuderendes læring
Lars Stig Andersen, Jeppe Emmersen & Jette Kolding Kristensen
03/04/2023
1 Mediebidrag
Presse/medie