Middle ear pressure regulation: Compliant structures counterbalancing pressure changes

Simona Padurariu

Middle ear pressure regulation: Compliant structures counterbalancing pressure changes

Bidragets oversatte titel: Regulering af mellemøretryk: Compliant strukturer med betydning ved trykændringer.

Simona Padurariu

Publikation: Ph.d.-afhandling

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Abstract

One of the most frequent otological diseases is otitis media with effusion. This condition consists of inflammatory changes within the middle ear, and accumulation of an under-atmospheric pressure. The consequences are often serious when the under-pressure persists for a long time, becoming chronic. In certain cases, the condition results in the formation of retraction pockets in the tympanic membrane, bone erosion, and cholesteatoma formation. This loss of structural integrity of the middle ear leads inevitably to hearing loss.
The treatment of chronic Otitis media with effusion requires often surgery. The success of surgical reconstruction depends on the restauration of the pressure balance between the middle ear and the ambient atmosphere. Therefore, the understanding of the basic mechanisms of the pressure regulation within the middle ear is essential.
The following work contributes evidence to the role of the main compliant structures of the middle ear, known to or hypothesized to influence the middle ear pressure.

Bidragets oversatte titel	Regulering af mellemøretryk: Compliant strukturer med betydning ved trykændringer.
Originalsprog	Engelsk
Vejledere	Gaihede, Michael, Hovedvejleder Vyberg, Mogens, Bivejleder Stensballe, Allan, Bivejleder
Udgiver	Aalborg Universitetsforlag
ISBN'er, elektronisk	978-87-7210-209-2
Status	Udgivet - 2018

Bibliografisk note

PhD supervisor:
Associate Professor, PhD, MD Michael Gaihede, Department of Otology, Head and Neck Surgery, Aalborg University Hospital, Department of Clinical Medicine
Aalborg University, Denmark

Assistant PhD supervisors:
Professor, MD Mogens Vyberg, Institute of Pathology, Aalborg University Hospital
Department of Clinical Medicine, Aalborg University, Denmark
Associate Professor, PhD, Allan Stensballe, Department of Health Science and Technology, Aalborg University, Denmark

Emneord

mellemøre fysiologi
mellemøre betændelse

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Citationsformater

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AB - One of the most frequent otological diseases is otitis media with effusion. This condition consists of inflammatory changes within the middle ear, and accumulation of an under-atmospheric pressure. The consequences are often serious when the under-pressure persists for a long time, becoming chronic. In certain cases, the condition results in the formation of retraction pockets in the tympanic membrane, bone erosion, and cholesteatoma formation. This loss of structural integrity of the middle ear leads inevitably to hearing loss.The treatment of chronic Otitis media with effusion requires often surgery. The success of surgical reconstruction depends on the restauration of the pressure balance between the middle ear and the ambient atmosphere. Therefore, the understanding of the basic mechanisms of the pressure regulation within the middle ear is essential. The following work contributes evidence to the role of the main compliant structures of the middle ear, known to or hypothesized to influence the middle ear pressure.

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