Associations between patients' risk attitude and their adherence to statin treatment: a population based questionnaire and register study

Benedicte Lind Barfoed; Maja Skov Paulsen; Palle Mark Christensen; Peder Andreas Halvorsen; Trine Kjær; Mogens Lytken Larsen; Pia Veldt Larsen; Jesper Bo Nielsen; Jens Søndergaard; Dorte Ejg Jarbøl

doi:10.1186/s12875-016-0423-1

Associations between patients' risk attitude and their adherence to statin treatment: a population based questionnaire and register study

Benedicte Lind Barfoed, Maja Skov Paulsen, Palle Mark Christensen, Peder Andreas Halvorsen, Trine Kjær, Mogens Lytken Larsen, Pia Veldt Larsen, Jesper Bo Nielsen, Jens Søndergaard, Dorte Ejg Jarbøl

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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Abstract

BACKGROUND: Poor adherence to medical treatment may have considerable consequences for the patients' health and for healthcare costs to society. The need to understand the determinants for poor adherence has motivated several studies on socio-demographics and comorbidity. Few studies focus on the association between risk attitude and adherence. The aim of the present study was to estimate associations between patients' adherence to statin treatment and different dimensions of risk attitude, and to identify subgroups of patients with poor adherence.

METHODS: Population-based questionnaire and register-based study on a sample of 6393 persons of the general. Danish population aged 20-79. Data on risk attitude were based on 4 items uncovering health-related as well as financial dimensions of risk attitude. They were collected through a web-based questionnaire and combined with register data on redeemed statin prescriptions, sociodemographics and comorbidity. Adherence was estimated by proportion of days covered using a cut-off point at 80 %.

RESULTS: For the dimension of health-related risk attitude, "Preference for GP visit when having symptoms", risk-neutral and risk-seeking patients had poorer adherence than the risk-averse patients, OR 0.80 (95 %-CI 0.68-0.95) and OR 0.83 (95 %-CI 0.71-0.98), respectively. No significant association was found between adherence and financial risk attitude. Further, patients in the youngest age group and patients with no CVD were less adherent to statin treatment.

CONCLUSION: We find some indication that risk attitude is associated with adherence to statin treatment, and that risk-neutral and risk-seeking patients may have poorer adherence than risk-averse patients. This is important for clinicians to consider when discussing optimal treatment decisions with their patients. The identified subgroups with the poorest adherence may deserve special attention from their GP regarding statin treatment.

Originalsprog	Engelsk
Artikelnummer	28
Tidsskrift	BMC Family Practice
Vol/bind	17
Udgave nummer	1
Antal sider	9
ISSN	1471-2296
DOI	https://doi.org/10.1186/s12875-016-0423-1
Status	Udgivet - 2016

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10.1186/s12875-016-0423-1

Open access articleForlagets udgivne version, 596 KBLicens: CC BY 4.0

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Barfoed, B. L., Paulsen, M. S., Christensen, P. M., Halvorsen, P. A., Kjær, T., Larsen, M. L., Larsen, P. V., Nielsen, J. B., Søndergaard, J., & Jarbøl, D. E. (2016). Associations between patients' risk attitude and their adherence to statin treatment: a population based questionnaire and register study. BMC Family Practice, 17(1), Artikel 28. https://doi.org/10.1186/s12875-016-0423-1

@article{97dc5cb0d1ab4edea05d82dee934099f,

title = "Associations between patients' risk attitude and their adherence to statin treatment: a population based questionnaire and register study",

abstract = "BACKGROUND: Poor adherence to medical treatment may have considerable consequences for the patients' health and for healthcare costs to society. The need to understand the determinants for poor adherence has motivated several studies on socio-demographics and comorbidity. Few studies focus on the association between risk attitude and adherence. The aim of the present study was to estimate associations between patients' adherence to statin treatment and different dimensions of risk attitude, and to identify subgroups of patients with poor adherence.METHODS: Population-based questionnaire and register-based study on a sample of 6393 persons of the general. Danish population aged 20-79. Data on risk attitude were based on 4 items uncovering health-related as well as financial dimensions of risk attitude. They were collected through a web-based questionnaire and combined with register data on redeemed statin prescriptions, sociodemographics and comorbidity. Adherence was estimated by proportion of days covered using a cut-off point at 80 %.RESULTS: For the dimension of health-related risk attitude, {"}Preference for GP visit when having symptoms{"}, risk-neutral and risk-seeking patients had poorer adherence than the risk-averse patients, OR 0.80 (95 %-CI 0.68-0.95) and OR 0.83 (95 %-CI 0.71-0.98), respectively. No significant association was found between adherence and financial risk attitude. Further, patients in the youngest age group and patients with no CVD were less adherent to statin treatment.CONCLUSION: We find some indication that risk attitude is associated with adherence to statin treatment, and that risk-neutral and risk-seeking patients may have poorer adherence than risk-averse patients. This is important for clinicians to consider when discussing optimal treatment decisions with their patients. The identified subgroups with the poorest adherence may deserve special attention from their GP regarding statin treatment.",

author = "Barfoed, {Benedicte Lind} and Paulsen, {Maja Skov} and Christensen, {Palle Mark} and Halvorsen, {Peder Andreas} and Trine Kj{\ae}r and Larsen, {Mogens Lytken} and Larsen, {Pia Veldt} and Nielsen, {Jesper Bo} and Jens S{\o}ndergaard and Jarb{\o}l, {Dorte Ejg}",

year = "2016",

doi = "10.1186/s12875-016-0423-1",

language = "English",

volume = "17",

journal = "BMC Family Practice",

issn = "1471-2296",

publisher = "BioMed Central",

number = "1",

}

TY - JOUR

T1 - Associations between patients' risk attitude and their adherence to statin treatment

T2 - a population based questionnaire and register study

AU - Barfoed, Benedicte Lind

AU - Paulsen, Maja Skov

AU - Christensen, Palle Mark

AU - Halvorsen, Peder Andreas

AU - Kjær, Trine

AU - Larsen, Mogens Lytken

AU - Larsen, Pia Veldt

AU - Nielsen, Jesper Bo

AU - Søndergaard, Jens

AU - Jarbøl, Dorte Ejg

PY - 2016

Y1 - 2016

N2 - BACKGROUND: Poor adherence to medical treatment may have considerable consequences for the patients' health and for healthcare costs to society. The need to understand the determinants for poor adherence has motivated several studies on socio-demographics and comorbidity. Few studies focus on the association between risk attitude and adherence. The aim of the present study was to estimate associations between patients' adherence to statin treatment and different dimensions of risk attitude, and to identify subgroups of patients with poor adherence.METHODS: Population-based questionnaire and register-based study on a sample of 6393 persons of the general. Danish population aged 20-79. Data on risk attitude were based on 4 items uncovering health-related as well as financial dimensions of risk attitude. They were collected through a web-based questionnaire and combined with register data on redeemed statin prescriptions, sociodemographics and comorbidity. Adherence was estimated by proportion of days covered using a cut-off point at 80 %.RESULTS: For the dimension of health-related risk attitude, "Preference for GP visit when having symptoms", risk-neutral and risk-seeking patients had poorer adherence than the risk-averse patients, OR 0.80 (95 %-CI 0.68-0.95) and OR 0.83 (95 %-CI 0.71-0.98), respectively. No significant association was found between adherence and financial risk attitude. Further, patients in the youngest age group and patients with no CVD were less adherent to statin treatment.CONCLUSION: We find some indication that risk attitude is associated with adherence to statin treatment, and that risk-neutral and risk-seeking patients may have poorer adherence than risk-averse patients. This is important for clinicians to consider when discussing optimal treatment decisions with their patients. The identified subgroups with the poorest adherence may deserve special attention from their GP regarding statin treatment.

AB - BACKGROUND: Poor adherence to medical treatment may have considerable consequences for the patients' health and for healthcare costs to society. The need to understand the determinants for poor adherence has motivated several studies on socio-demographics and comorbidity. Few studies focus on the association between risk attitude and adherence. The aim of the present study was to estimate associations between patients' adherence to statin treatment and different dimensions of risk attitude, and to identify subgroups of patients with poor adherence.METHODS: Population-based questionnaire and register-based study on a sample of 6393 persons of the general. Danish population aged 20-79. Data on risk attitude were based on 4 items uncovering health-related as well as financial dimensions of risk attitude. They were collected through a web-based questionnaire and combined with register data on redeemed statin prescriptions, sociodemographics and comorbidity. Adherence was estimated by proportion of days covered using a cut-off point at 80 %.RESULTS: For the dimension of health-related risk attitude, "Preference for GP visit when having symptoms", risk-neutral and risk-seeking patients had poorer adherence than the risk-averse patients, OR 0.80 (95 %-CI 0.68-0.95) and OR 0.83 (95 %-CI 0.71-0.98), respectively. No significant association was found between adherence and financial risk attitude. Further, patients in the youngest age group and patients with no CVD were less adherent to statin treatment.CONCLUSION: We find some indication that risk attitude is associated with adherence to statin treatment, and that risk-neutral and risk-seeking patients may have poorer adherence than risk-averse patients. This is important for clinicians to consider when discussing optimal treatment decisions with their patients. The identified subgroups with the poorest adherence may deserve special attention from their GP regarding statin treatment.

U2 - 10.1186/s12875-016-0423-1

DO - 10.1186/s12875-016-0423-1

M3 - Journal article

C2 - 26956487

SN - 1471-2296

VL - 17

JO - BMC Family Practice

JF - BMC Family Practice

IS - 1

M1 - 28

ER -

Associations between patients' risk attitude and their adherence to statin treatment: a population based questionnaire and register study

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