Brain state-dependent peripheral nerve stimulation for plasticity induction in stroke patients

Andrew James Thomas Stevenson, Helle Rovsing Møller Jørgensen, Kåre Eg Severinsen, Susan Aliakbaryhosseinabadi, Ning Jiang, Dario Farina, Natalie Mrachacz-Kersting

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Abstract

Artificial activation of peripheral afferent fibers, with the resulting sensory feedback timed to arrive at the peak negativity of the movement-related cortical potential, induces significant increases in the excitability of cortical projections to the target muscle in healthy individuals and chronic stroke patients. In the currently ongoing study, we applied this associative brain- computer interface paradigm to sub-acute stroke patients. Compared to a sham group, where the peripheral electrical stimulation intensity was below the acti- vation threshold of the sensory afferents, the associative intervention group displayed substantial increases in corticospinal excitability to the target muscle (tibialis anterior).
OriginalsprogEngelsk
TitelConverging Clinical and Engineering Research on Neurorehabilitation III : Proceedings of the 4th International Conference on NeuroRehabilitation (ICNR2018), October 16–20, 2018, Pisa, Italy
RedaktørerLorenzo Masia, Silvestro Micera, Metin Akay, José L. Pons
Antal sider5
ForlagSpringer
Publikationsdato2019
Sider1066-1070
ISBN (Trykt)978-3-030-01844
ISBN (Elektronisk)978-3-030-01845-0
DOI
StatusUdgivet - 2019
BegivenhedInternational Conference on Neurorehabilitation - Pisa, Italien
Varighed: 16 okt. 201820 okt. 2018
http://www.icnr2018.org

Konference

KonferenceInternational Conference on Neurorehabilitation
Land/OmrådeItalien
ByPisa
Periode16/10/201820/10/2018
Internetadresse
NavnBiosystems and Biorobotics
Nummer21
ISSN2195-3562

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