Cardiac abnormalities in adult patients with polymyositis or dermatomyositis as assessed by noninvasive modalities

L P Diederichsen; J A Simonsen; A C Diederichsen; Svend Hvidsten; M Hougaard; P Junker; K Søndergaard; I E Lundberg; N Tvede; Ncf Sandgaard; A F Christensen; L Dreyer; S Kay; K S Eskerud; H Petersen; L Ejstrup; Søren Jacobsen

doi:10.1002/acr.22772

Cardiac abnormalities in adult patients with polymyositis or dermatomyositis as assessed by noninvasive modalities

L P Diederichsen, J A Simonsen, A C Diederichsen, Svend Hvidsten, M Hougaard, P Junker, K Søndergaard, I E Lundberg, N Tvede, Ncf Sandgaard, A F Christensen, L Dreyer, S Kay, K S Eskerud, H Petersen, L Ejstrup, Søren Jacobsen

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

50 Citationer (Scopus)

Abstract

Objectives Cardiac events are a major cause of death in patients with idiopathic inflammatory myopathies (IIM). The study objective was in a controlled setting to describe cardiac abnormalities by non-invasive methods in a cohort of patients with polymyositis (PM) or dermatomyositis (DM) and to identify predictors for cardiac dysfunction. Methods In a cross-sectional study, 76 patients with PM/DM and 48 matched healthy controls (HC) were assessed by serum levels of cardiac troponin-I (TnI), electrocardiography, Holter monitoring, echocardiography with tissue Doppler imaging (TDI) and quantitative cardiac (99m) technetium pyrophosphate ((99m) Tc-PYP) scintigraphy. Results Compared to HCs, patients with PM/DM more frequently had left ventricular diastolic dysfunction (LVDD) (12% vs. 0%, P = 0.02) and longer QRS and QTc intervals (P = 0.007 and P

Originalsprog	Engelsk
Tidsskrift	Arthritis Care & Research
Vol/bind	68
Udgave nummer	7
Sider (fra-til)	1012-1020
Antal sider	9
ISSN	2151-464X
DOI	https://doi.org/10.1002/acr.22772
Status	Udgivet - 2016
Udgivet eksternt	Ja

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10.1002/acr.22772

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Citationsformater

Diederichsen, L. P., Simonsen, J. A., Diederichsen, A. C., Hvidsten, S., Hougaard, M., Junker, P., Søndergaard, K., Lundberg, I. E., Tvede, N., Sandgaard, N., Christensen, A. F., Dreyer, L., Kay, S., Eskerud, K. S., Petersen, H., Ejstrup, L., & Jacobsen, S. (2016). Cardiac abnormalities in adult patients with polymyositis or dermatomyositis as assessed by noninvasive modalities. Arthritis Care & Research, 68(7), 1012-1020. https://doi.org/10.1002/acr.22772

@article{6beeaab5b2204a8785df5afae5641b69,

title = "Cardiac abnormalities in adult patients with polymyositis or dermatomyositis as assessed by noninvasive modalities",

abstract = "Objectives Cardiac events are a major cause of death in patients with idiopathic inflammatory myopathies (IIM). The study objective was in a controlled setting to describe cardiac abnormalities by non-invasive methods in a cohort of patients with polymyositis (PM) or dermatomyositis (DM) and to identify predictors for cardiac dysfunction. Methods In a cross-sectional study, 76 patients with PM/DM and 48 matched healthy controls (HC) were assessed by serum levels of cardiac troponin-I (TnI), electrocardiography, Holter monitoring, echocardiography with tissue Doppler imaging (TDI) and quantitative cardiac (99m) technetium pyrophosphate ((99m) Tc-PYP) scintigraphy. Results Compared to HCs, patients with PM/DM more frequently had left ventricular diastolic dysfunction (LVDD) (12% vs. 0%, P = 0.02) and longer QRS and QTc intervals (P = 0.007 and P ",

author = "Diederichsen, {L P} and Simonsen, {J A} and Diederichsen, {A C} and Svend Hvidsten and M Hougaard and P Junker and K S{\o}ndergaard and Lundberg, {I E} and N Tvede and Ncf Sandgaard and Christensen, {A F} and L Dreyer and S Kay and Eskerud, {K S} and H Petersen and L Ejstrup and S{\o}ren Jacobsen",

year = "2016",

doi = "10.1002/acr.22772",

language = "English",

volume = "68",

pages = "1012--1020",

journal = "Arthritis Care & Research",

issn = "2151-464X",

publisher = "Wiley",

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Diederichsen, LP, Simonsen, JA, Diederichsen, AC, Hvidsten, S, Hougaard, M, Junker, P, Søndergaard, K, Lundberg, IE, Tvede, N, Sandgaard, N, Christensen, AF, Dreyer, L, Kay, S, Eskerud, KS, Petersen, H, Ejstrup, L & Jacobsen, S 2016, 'Cardiac abnormalities in adult patients with polymyositis or dermatomyositis as assessed by noninvasive modalities', Arthritis Care & Research, bind 68, nr. 7, s. 1012-1020. https://doi.org/10.1002/acr.22772

TY - JOUR

T1 - Cardiac abnormalities in adult patients with polymyositis or dermatomyositis as assessed by noninvasive modalities

AU - Diederichsen, L P

AU - Simonsen, J A

AU - Diederichsen, A C

AU - Hvidsten, Svend

AU - Hougaard, M

AU - Junker, P

AU - Søndergaard, K

AU - Lundberg, I E

AU - Tvede, N

AU - Sandgaard, Ncf

AU - Christensen, A F

AU - Dreyer, L

AU - Kay, S

AU - Eskerud, K S

AU - Petersen, H

AU - Ejstrup, L

AU - Jacobsen, Søren

PY - 2016

Y1 - 2016

N2 - Objectives Cardiac events are a major cause of death in patients with idiopathic inflammatory myopathies (IIM). The study objective was in a controlled setting to describe cardiac abnormalities by non-invasive methods in a cohort of patients with polymyositis (PM) or dermatomyositis (DM) and to identify predictors for cardiac dysfunction. Methods In a cross-sectional study, 76 patients with PM/DM and 48 matched healthy controls (HC) were assessed by serum levels of cardiac troponin-I (TnI), electrocardiography, Holter monitoring, echocardiography with tissue Doppler imaging (TDI) and quantitative cardiac (99m) technetium pyrophosphate ((99m) Tc-PYP) scintigraphy. Results Compared to HCs, patients with PM/DM more frequently had left ventricular diastolic dysfunction (LVDD) (12% vs. 0%, P = 0.02) and longer QRS and QTc intervals (P = 0.007 and P

AB - Objectives Cardiac events are a major cause of death in patients with idiopathic inflammatory myopathies (IIM). The study objective was in a controlled setting to describe cardiac abnormalities by non-invasive methods in a cohort of patients with polymyositis (PM) or dermatomyositis (DM) and to identify predictors for cardiac dysfunction. Methods In a cross-sectional study, 76 patients with PM/DM and 48 matched healthy controls (HC) were assessed by serum levels of cardiac troponin-I (TnI), electrocardiography, Holter monitoring, echocardiography with tissue Doppler imaging (TDI) and quantitative cardiac (99m) technetium pyrophosphate ((99m) Tc-PYP) scintigraphy. Results Compared to HCs, patients with PM/DM more frequently had left ventricular diastolic dysfunction (LVDD) (12% vs. 0%, P = 0.02) and longer QRS and QTc intervals (P = 0.007 and P

U2 - 10.1002/acr.22772

DO - 10.1002/acr.22772

M3 - Journal article

SN - 2151-464X

VL - 68

SP - 1012

EP - 1020

JO - Arthritis Care & Research

JF - Arthritis Care & Research

IS - 7

ER -