Cell-based therapy for the treatment of female stress urinary incontinence: an early cost–effectiveness analysis

Bidragets oversatte titel: Cellebaseret terapi til behandling af kvindelig stressininkontinens: en tidlig omkostningseffektivitetsanalyse

Andreas Westh Vilsbøll, Jakob Munk Mouritsen, Line Park Jensen, Nikolaj Bødker, Annette Willemoes Holst, Cristian Pablo Pennisi, Lars Holger Ehlers

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

7 Citationer (Scopus)
299 Downloads (Pure)

Abstract

Aim: To perform an early cost-effectiveness analysis of in vitro expanded myoblasts (IVM) and minced myofibers versus midurethral slings (MUS) for surgical treatment of female stress urinary incontinence. Methods: Cost-effectiveness and sensitivity analyses were performed using a decision tree comprising previously published data and expert opinions. Results & conclusion: In the base case scenario, MUS was the cost-effective strategy with a negative incremental cost-effectiveness ratio compared with IVM and a positive incremental cost-effectiveness ratio compared with minced myofibers. However, the sensitivity analysis indicates that IVM may become an alternative providing greater effect at a higher cost. With the possibility of becoming more effective, IVM treatment would be advantageous over MUS given its reduced invasiveness and lower risks of complications.

Bidragets oversatte titelCellebaseret terapi til behandling af kvindelig stressininkontinens: en tidlig omkostningseffektivitetsanalyse
OriginalsprogEngelsk
TidsskriftRegenerative Medicine
Vol/bind13
Udgave nummer3
Sider (fra-til)321-330
Antal sider10
ISSN1746-0751
DOI
StatusUdgivet - 1 maj 2018

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