Circadian lighting has the potential to be used as a welfare technology, and improve the health and well-being of the general public. A research-based dynamic circadian lighting scheme can be developed using LED lighting. Testing and evaluating circadian lighting however requires a holistic approach, bringing together several different disciplines, in particular technological, medical and anthropological fields. The analysis of the tests must combine qualitative and quantitative data, and requires the use of a mixed methods approach. This paper presents the framework for such analysis for designing the evaluation of circadian adjusted lighting.