Detecting reduced renal function in children: Comparison of GFR-models and serum markers

Trine Borup Andersen; Lars Jødal; Erland J Erlandsen; Anni Morsing; Jørgen Frøkiær; Jens Brøchner-Mortensen

doi:10.1007/s00467-012-2268-8

Detecting reduced renal function in children: Comparison of GFR-models and serum markers

Trine Borup Andersen, Lars Jødal, Erland J Erlandsen, Anni Morsing, Jørgen Frøkiær, Jens Brøchner-Mortensen

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

13 Citationer (Scopus)

Abstract

The aim of this study was to compare the ability of renal indicators [serum creatinine (SCr), cystatin C (SCysC)] and glomerular filtration rate (GFR)-models to discriminate normal and reduced renal function. As a single cut-off level will always lead to false classifications, we propose using two cut-off levels, dividing renal function into normal or reduced, with an intermediate "gray zone" of indeterminable results.

Originalsprog	Engelsk
Tidsskrift	Pediatric Nephrology
Vol/bind	28
Udgave nummer	1
Sider (fra-til)	83-92
Antal sider	10
ISSN	0931-041X
DOI	https://doi.org/10.1007/s00467-012-2268-8
Status	Udgivet - jan. 2013

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10.1007/s00467-012-2268-8

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abstract = "The aim of this study was to compare the ability of renal indicators [serum creatinine (SCr), cystatin C (SCysC)] and glomerular filtration rate (GFR)-models to discriminate normal and reduced renal function. As a single cut-off level will always lead to false classifications, we propose using two cut-off levels, dividing renal function into normal or reduced, with an intermediate {"}gray zone{"} of indeterminable results.",

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author = "Andersen, {Trine Borup} and Lars J{\o}dal and Erlandsen, {Erland J} and Anni Morsing and J{\o}rgen Fr{\o}ki{\ae}r and Jens Br{\o}chner-Mortensen",

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T2 - Comparison of GFR-models and serum markers

AU - Andersen, Trine Borup

AU - Jødal, Lars

AU - Erlandsen, Erland J

AU - Morsing, Anni

AU - Frøkiær, Jørgen

AU - Brøchner-Mortensen, Jens

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N2 - The aim of this study was to compare the ability of renal indicators [serum creatinine (SCr), cystatin C (SCysC)] and glomerular filtration rate (GFR)-models to discriminate normal and reduced renal function. As a single cut-off level will always lead to false classifications, we propose using two cut-off levels, dividing renal function into normal or reduced, with an intermediate "gray zone" of indeterminable results.

AB - The aim of this study was to compare the ability of renal indicators [serum creatinine (SCr), cystatin C (SCysC)] and glomerular filtration rate (GFR)-models to discriminate normal and reduced renal function. As a single cut-off level will always lead to false classifications, we propose using two cut-off levels, dividing renal function into normal or reduced, with an intermediate "gray zone" of indeterminable results.

KW - Adolescent

KW - Child

KW - Child, Preschool

KW - Creatinine

KW - Cystatin C

KW - Female

KW - Glomerular Filtration Rate

KW - Humans

KW - Kidney Diseases

KW - Kidney Function Tests

KW - Male

U2 - 10.1007/s00467-012-2268-8

DO - 10.1007/s00467-012-2268-8

M3 - Journal article

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SN - 0931-041X

VL - 28

SP - 83

EP - 92

JO - Pediatric Nephrology

JF - Pediatric Nephrology

IS - 1

ER -

Detecting reduced renal function in children: Comparison of GFR-models and serum markers

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