Evaluation of pupillary function in thyroid disease

Employing the technique of infrared television pupillography, the pupil area in darkness, pupillary unrest, and various parameters of the light response were measured in 5 patients with clinical and biochemical overt thyrotoxicosis and in 2 patients with longstanding severe primary myxoedema. The patients were studied before and after medical treatment. The treatments did not induce significant alterations in any of the parameters measured. Thus pupillary measurements are not a convenient method for recording of peripheral thyroid hormone action.