Abstract
Many autoimmune diseases like rheumatoid arthritis (RA) show gender differences. RA is triggered by an interaction between genetic, hormonal, environmental and behavioural factors. 75% of cases are women under the age of 60; lover the age 60 the gender ratio is 1:1. Different genotypes predispose for RA. Pregnancy often suppresses RA, as does oral contraception. Lactation, smoking (w), BMI > 30, heavy vibrations and certain dust particles (m) may trigger RA, while the effect of male hormones is uncertain. Future prevention should focus on environment, behavioural factors and genetic profiling.
Originalsprog | Dansk |
---|---|
Tidsskrift | Ugeskrift for Laeger |
Vol/bind | 169 |
Udgave nummer | 25 |
Sider (fra-til) | 2440-2442 |
Antal sider | 3 |
ISSN | 0041-5782 |
Status | Udgivet - 2007 |
Udgivet eksternt | Ja |
Emneord
- Arthritis, Rheumatoid
- Environmental Exposure
- Female
- Genetic Predisposition to Disease
- Humans
- Life Style
- Male
- Menopause
- Pregnancy
- Sex Characteristics
- Sex Factors
- Socioeconomic Factors