Overdispersion in allelic counts and θ-correction in forensic genetics

Torben Tvedebrink

doi:10.1016/j.fsigss.2009.08.014

Overdispersion in allelic counts and θ-correction in forensic genetics

Torben Tvedebrink

Institut for Matematiske Fag

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

2 Citationer (Scopus)

Abstract

Udgivelsesdato: December

Originalsprog	Engelsk
Tidsskrift	Forensic Science International
Vol/bind	2
Udgave nummer	1
Sider (fra-til)	455-457
ISSN	0379-0738
DOI	https://doi.org/10.1016/j.fsigss.2009.08.014
Status	Udgivet - 2009

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10.1016/j.fsigss.2009.08.014

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@article{b381e110b70011debd73000ea68e967b,

title = "Overdispersion in allelic counts and θ-correction in forensic genetics",

abstract = "A statistical model for incorporating the extra variability in allelic counts due to subpopulation structures is presented. In forensic genetics, this effect is modelled by the identical-by-decent-parameter, θ. It is shown, that θ may be defined as an overdispersion parameter capturing the extra variability from subpopulation structures. This allows derivation of maximum likelihood estimates of the allele probabilities and θ together with the computation of profile log-likelihood, confidence intervals and hypothesis testing.",

author = "Torben Tvedebrink",

year = "2009",

doi = "10.1016/j.fsigss.2009.08.014",

language = "English",

volume = "2",

pages = "455--457",

journal = "Forensic Science International",

issn = "0379-0738",

publisher = "Elsevier",

number = "1",

}

TY - JOUR

T1 - Overdispersion in allelic counts and θ-correction in forensic genetics

AU - Tvedebrink, Torben

PY - 2009

Y1 - 2009

N2 - A statistical model for incorporating the extra variability in allelic counts due to subpopulation structures is presented. In forensic genetics, this effect is modelled by the identical-by-decent-parameter, θ. It is shown, that θ may be defined as an overdispersion parameter capturing the extra variability from subpopulation structures. This allows derivation of maximum likelihood estimates of the allele probabilities and θ together with the computation of profile log-likelihood, confidence intervals and hypothesis testing.

AB - A statistical model for incorporating the extra variability in allelic counts due to subpopulation structures is presented. In forensic genetics, this effect is modelled by the identical-by-decent-parameter, θ. It is shown, that θ may be defined as an overdispersion parameter capturing the extra variability from subpopulation structures. This allows derivation of maximum likelihood estimates of the allele probabilities and θ together with the computation of profile log-likelihood, confidence intervals and hypothesis testing.

U2 - 10.1016/j.fsigss.2009.08.014

DO - 10.1016/j.fsigss.2009.08.014

M3 - Journal article

SN - 0379-0738

VL - 2

SP - 455

EP - 457

JO - Forensic Science International

JF - Forensic Science International

IS - 1

ER -

Overdispersion in allelic counts and θ-correction in forensic genetics

Abstract

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