Projects per year
Organisation profile
Organisation profile
Research centre name:
Centre for Neuroplasticity and Pain
Date of establishment and expected operational period of the centre:
2015-2025
Initials of research centre:
CNAP
Head of research centre:
Prof. Thomas Graven-Nielsen
Participants and partners?
CNAP consists of researchers from four different research groups at AAU:
- Neural Engineering and Neurophysiology
- Integrative Neuroscience
- Pain and Motor System Plasticity
- Translational Pain Biomarkers
Who are we?
Center for Neuroplasticity and Pain (CNAP) is a Center of Excellence at the Department of Health Science and Technology, funded by the Danish National Research Foundation in the period 2015-2025.
What are our fundamental goals/objectives?
The ambition of CNAP is to identify and modulate key features of human pain neuroplasticity. We keenly believe that this can be achieved through a systematic engineering approach, including provoking, probing and modulation of the dynamic neuroplastic properties of the pain system.
Our research – what we do?
CNAP applies a basic research approach where new advanced biomedical provocation and probing platforms are being discovered and applied to study novel aspects of the human pain neuroplasticity. When an injury results in acute pain, the nervous system undergoes an adaptive neuroplastic response resulting in an increase in sensitivity. After some time, the pain neuroplasticity is normalized as the injury heals. In some cases, such neuroplastic processes fail to normalize during convalescence, and acute pain develops into chronic pain with hypersensitivity. The continuing pain after injury resolution may be caused by maladaptive pain neuroplasticity. In contrast, advantageous neuroplasticity permits the nervous system to cope with challenges such as maladaptive pain neuroplasticity to help returning to a pain-free state.
Interdisciplinary, international cooperation, and research training combined with the capacity of leading researchers is the core research philosophy of CNAP. Thus, all our research groups are highly interdisciplinary and include experts within e.g. biomedical engineering, neuropsychology, pharmacology, biophysics, and medicine. To secure international excellence, CNAP strives for an equal distribution between genders and between national and international staff.
How does our research contribute to societal health challenges?
Chronic pain is a key societal challenge: it affects one out of five adults, and is generally poorly treated. Through the research we conduct at CNAP, we contribute to improving pain treatments.
How are we funded?
CNAP is funded by the Danish National Research Foundation (DNRF121) and by the European Union’s Horizon 2020 research and innovation programme (Marie Skłodowska-Curie grant agreement No 754465).
Who are our key collaborators?
CNAP cooperates with several renowned national and international researchers. In addition, a number of international collaborators are embedded within CNAP and participate actively in the centre’s activities.
Collaborations from the last five years
Profiles
-
Giulia Erica Aliotta
- The Faculty of Medicine - Post.Doc.
- Department of Health Science and Technology - Post.Doc.
- Translational Biomarkers in Pain and Precision Medicine - Post.Doc.
- Center for Neuroplasticity and Pain
Person: VIP
-
Trine Andresen
- The Faculty of Medicine - Post.Doc.
- Department of Health Science and Technology - Post.Doc.
- Integrative Neuroscience - Post.Doc.
- Pain and Motor System Plasticity - Post.Doc.
- Center for Neuroplasticity and Pain
Person: VIP
-
C19 Symptom Mapping
Boudreau, S., Bøggild, H., Duroux, M. & Holden, S.
26/03/2020 → …
Project: Research
-
Investigation of temporal and spatial integration of pain information in the nociceptive system
Rujoie, A.
01/11/2019 → …
Project: Research
-
Effortless Listening using Brain Feedback
Østergaard, J., Andersen, O. K., Arguissain, F., Baboukani, P. S. & Mohammadi, Y.
01/09/2019 → …
Project: Research
Research output
-
A potential link between inflammatory profiles, clinical pain, pain catastrophizing and long-term outcomes after total knee arthroplasty surgery
Giordano, R., Capriotti, C., Gerra, M. C., Kappel, A., Østgaard, S. E., Dallabona, C., Arendt-Nielsen, L. & Petersen, K. K-S., 26 Feb 2024, (E-pub ahead of print) In: European Journal of Pain.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
Bridging the translational gap: adenosine as a modulator of neuropathic pain in preclinical models and humans
Arendt-Nielsen, L., Klitgaard, H. & Hansen, S. N., Jan 2024, In: Scandinavian Journal of Pain. 24, 1, 20230048.Research output: Contribution to journal › Review article › peer-review
Open AccessFile4 Downloads (Pure) -
Decreased Resting-State Alpha Self-Synchronization in Depressive Disorder
Mohammadi, Y., Kafraj, M. S., Graversen, C. & Moradi, M. H., Mar 2024, In: Clinical EEG and Neuroscience. 55, 2, p. 185-191 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Datasets
-
Diagnostic Accuracy of Perception Threshold Tracking in the Detection of Small Fiber Damage in Type 1 Diabetes
Røikjer, J. (Creator), Croosu , S. S. (Creator), Sejergaard, B. F. (Creator), Hansen, T. M. S. (Creator), Frøkjær, J. B. (Creator), Søndergaard, C. B. (Creator), Petropoulos, I. N. (Creator), Malik, R. A. (Creator), Nielsen, E. (Creator), Mørch, C. D. (Creator) & Ejskjær, N. (Creator), Sage Journals, 2023
DOI: 10.25384/sage.c.6445639, https://sage.figshare.com/collections/Diagnostic_Accuracy_of_Perception_Threshold_Tracking_in_the_Detection_of_Small_Fiber_Damage_in_Type_1_Diabetes/6445639
Dataset
-
Diagnostic Accuracy of Perception Threshold Tracking in the Detection of Small Fiber Damage in Type 1 Diabetes
Røikjer, J. (Creator), Croosu , S. S. (Creator), Sejergaard, B. F. (Creator), Hansen, T. M. S. (Creator), Frøkjær, J. B. (Creator), Søndergaard, C. B. (Creator), Petropoulos, I. N. (Creator), Malik, R. A. (Creator), Nielsen, E. (Creator), Mørch, C. D. (Creator) & Ejskjær, N. (Creator), Sage Journals, 2023
DOI: 10.25384/sage.c.6445639.v1, https://sage.figshare.com/collections/Diagnostic_Accuracy_of_Perception_Threshold_Tracking_in_the_Detection_of_Small_Fiber_Damage_in_Type_1_Diabetes/6445639/1
Dataset
-
Supplementary Material for: Serological Biomarkers at Hospital Admission Are Not Related to Long-Term Post-COVID Fatigue and Dyspnea in COVID-19 Survivors
Fernández-De-Las-Penãs, C. (Creator), Ryan-Murua, P. (Creator), Rodríguez-Jiménez, J. (Creator), Palacios-Cenã, M. (Creator), Arendt-Nielsen, L. (Creator) & Torres-Macho, J. (Creator), Karger Publishers, 5 Apr 2022
DOI: 10.6084/m9.figshare.19518862.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Serological_Biomarkers_at_Hospital_Admission_Are_Not_Related_to_Long-Term_Post-COVID_Fatigue_and_Dyspnea_in_COVID-19_Survivors/19518862/1
Dataset: Supplementary material
Prizes
-
3rd Best Paper Award
Rettore Andreis, Felipe (Recipient), Jensen, Winnie (Recipient), Janjua, Taha (Recipient), Meijs, Suzan (Recipient) & Nielsen, Thomas Gomes Nørgaard dos Santos (Recipient), Oct 2023
Prize: Conference prizes
-
-
The Svend Andersen Talent Prize 2022
Petersen, Kristian Kjær-Staal (Recipient), 2022
Prize: Honorary prizes and appointments
Activities
-
Brain Awareness Week 2024 Aalborg University
Thomas Alrik Sørensen (Lecturer), Carsten Dahl Mørch (Lecturer) & Chalotte Glintborg (Lecturer)
15 Mar 2024Activity: Talks and presentations › Talks and presentations in private or public companies
-
French National Research Agency – ANR (Member of Integrative and Cognitive Neuroscience panel) (External organisation)
Thomas Graven-Nielsen (Member)
2024 → …Activity: Memberships › Membership of committees, commissions, boards, councils, associations, organisations, or similar
-
PhD Defense Pernille Døssing Kwateng Diasso (Event)
Daniel Ciampi de Andrade (Member)
21 Apr 2023Activity: Memberships › Membership of review committee
File
Press/Media
-
Populære opioid-piller er vanvittigt vanedannende og kan stoppe vejrtrækningen
29/02/2024
2 items of Media coverage
Press/Media: Press / Media
-
Behandling af fantomsmerter hos amputerede
Romulus Lontis & Winnie Jensen
20/02/2024
1 item of Media coverage
Press/Media: Press / Media
-
Debat: Nye muligheder for diagnosticering af neuropati
20/02/2024
1 item of Media coverage
Press/Media: Press / Media