- Carlsen, Thomas Gelsing (Project participant)
- Birkelund, Svend (Project Manager, academic)
- Deleuran, Bent, Aarhus University, Denmark (Working partner)
- Christiansen, Gunna, Aarhus University, Denmark (Project participant)
- Hjelholt, Astrid , Aarhus University, Denmark (Project participant)
- Århus Universitet
- Århus Universitetshospital
- Loke Diagnostics
The purpose of this project is to examine the role of the HLA-B27 genotype and human mitochondrial heat shock protein 60 (HSP60) in the development of the spondyloarthrotpathies (SpAs), to find the mechanism of how an autoimmune disease that is dominated by CD4 + T helper cells can be genetically linked to a MHC class I tissue type. In addition to uncover the mechanism of how an infection can result in the development of reactive arthritis and whether this mechanism can generally explain the development of the SpAs.
| Status | Current |
|---|---|
| Period | 01-12-11 → 01-12-12 |
Keywords
- Autoimmune disease, Bacterial Infection, Heat shock protein
Publications
Increased levels of IgG antibodies against human HSP60 in patients with spondyloarthritis
Publication: Research - peer-review › Journal article
IgG subclass antibodies to human and bacterial HSP60 are not associated with disease activity and progression over time in axial spondyloarthritis
Publication: Research - peer-review › Journal article
ID: 60377527