Abstract
Chronic pain following surgery, persistent postsurgical pain, is an important highly prevalent condition contributing to significant symptom burden and lower quality of life. Persistent postsurgical pain is relatively refractory to treatment hence generating a high need for preventive strategies and treatments. Therefore, the identification of patients at risk of developing persistent pain is an area of active ongoing research. Recently it was demonstrated that peri-operative disruptions in central pain processing may be able to predict persistent postsurgical pain at long term follow-up in breast cancer patients. The aim of the current report is to present a short protocol to obtain pain thresholds to different stimuli at multiple sites and a measure of endogenous analgesia in breast cancer patients. We have used this method successfully in a clinical context and detail some representative results from a clinical study.
Original language | English |
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Article number | e56918 |
Journal | Journal of Visualized Experiments |
Volume | 2018 |
Issue number | 131 |
ISSN | 1940-087X |
DOIs | |
Publication status | Published - 18 Jan 2018 |
Keywords
- Breast cancer surgery
- Chronic postsurgical pain
- Conditioned pain modulation
- Diffuse noxious inhibitory controls
- Issue 131
- Medicine
- Pain threshold
- Persistent postsurgical pain
- Quantitative sensory testing