Atrial fibrillation

Gregory Y H Lip; Laurent Fauchier; Saul B Freedman; Isabelle Van Gelder; Andrea Natale; Carola Gianni; Stanley Nattel; Tatjana Potpara; Michiel Rienstra; Hung-Fat Tse; Deirdre A Lane

doi:10.1038/nrdp.2016.16

Atrial fibrillation

Gregory Y H Lip, Laurent Fauchier, Saul B Freedman, Isabelle Van Gelder, Andrea Natale, Carola Gianni, Stanley Nattel, Tatjana Potpara, Michiel Rienstra, Hung-Fat Tse, Deirdre A Lane

Research output: Contribution to journal › Review article › peer-review

201 Citations (Scopus)

Abstract

Atrial fibrillation (AF) is the most common sustained cardiac rhythm disorder, and increases in prevalence with increasing age and the number of cardiovascular comorbidities. AF is characterized by a rapid and irregular heartbeat that can be asymptomatic or lead to symptoms such as palpitations, dyspnoea and dizziness. The condition can also be associated with serious complications, including an increased risk of stroke. Important recent developments in the clinical epidemiology and management of AF have informed our approach to this arrhythmia. This Primer provides a comprehensive overview of AF, including its epidemiology, mechanisms and pathophysiology, diagnosis, screening, prevention and management. Management strategies, including stroke prevention, rate control and rhythm control, are considered. We also address quality of life issues and provide an outlook on future developments and ongoing clinical trials in managing this common arrhythmia.

Original language	English
Article number	16016
Journal	Nature Reviews. Disease Primers
Volume	2
Number of pages	26
ISSN	2056-676X
DOIs	https://doi.org/10.1038/nrdp.2016.16
Publication status	Published - 2016

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title = "Atrial fibrillation",

abstract = "Atrial fibrillation (AF) is the most common sustained cardiac rhythm disorder, and increases in prevalence with increasing age and the number of cardiovascular comorbidities. AF is characterized by a rapid and irregular heartbeat that can be asymptomatic or lead to symptoms such as palpitations, dyspnoea and dizziness. The condition can also be associated with serious complications, including an increased risk of stroke. Important recent developments in the clinical epidemiology and management of AF have informed our approach to this arrhythmia. This Primer provides a comprehensive overview of AF, including its epidemiology, mechanisms and pathophysiology, diagnosis, screening, prevention and management. Management strategies, including stroke prevention, rate control and rhythm control, are considered. We also address quality of life issues and provide an outlook on future developments and ongoing clinical trials in managing this common arrhythmia.",

author = "Lip, {Gregory Y H} and Laurent Fauchier and Freedman, {Saul B} and {Van Gelder}, Isabelle and Andrea Natale and Carola Gianni and Stanley Nattel and Tatjana Potpara and Michiel Rienstra and Hung-Fat Tse and Lane, {Deirdre A}",

year = "2016",

doi = "10.1038/nrdp.2016.16",

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volume = "2",

journal = "Nature Reviews. Disease Primers",

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TY - JOUR

T1 - Atrial fibrillation

AU - Lip, Gregory Y H

AU - Fauchier, Laurent

AU - Freedman, Saul B

AU - Van Gelder, Isabelle

AU - Natale, Andrea

AU - Gianni, Carola

AU - Nattel, Stanley

AU - Potpara, Tatjana

AU - Rienstra, Michiel

AU - Tse, Hung-Fat

AU - Lane, Deirdre A

PY - 2016

Y1 - 2016

N2 - Atrial fibrillation (AF) is the most common sustained cardiac rhythm disorder, and increases in prevalence with increasing age and the number of cardiovascular comorbidities. AF is characterized by a rapid and irregular heartbeat that can be asymptomatic or lead to symptoms such as palpitations, dyspnoea and dizziness. The condition can also be associated with serious complications, including an increased risk of stroke. Important recent developments in the clinical epidemiology and management of AF have informed our approach to this arrhythmia. This Primer provides a comprehensive overview of AF, including its epidemiology, mechanisms and pathophysiology, diagnosis, screening, prevention and management. Management strategies, including stroke prevention, rate control and rhythm control, are considered. We also address quality of life issues and provide an outlook on future developments and ongoing clinical trials in managing this common arrhythmia.

AB - Atrial fibrillation (AF) is the most common sustained cardiac rhythm disorder, and increases in prevalence with increasing age and the number of cardiovascular comorbidities. AF is characterized by a rapid and irregular heartbeat that can be asymptomatic or lead to symptoms such as palpitations, dyspnoea and dizziness. The condition can also be associated with serious complications, including an increased risk of stroke. Important recent developments in the clinical epidemiology and management of AF have informed our approach to this arrhythmia. This Primer provides a comprehensive overview of AF, including its epidemiology, mechanisms and pathophysiology, diagnosis, screening, prevention and management. Management strategies, including stroke prevention, rate control and rhythm control, are considered. We also address quality of life issues and provide an outlook on future developments and ongoing clinical trials in managing this common arrhythmia.

U2 - 10.1038/nrdp.2016.16

DO - 10.1038/nrdp.2016.16

M3 - Review article

C2 - 27159789

SN - 2056-676X

VL - 2

JO - Nature Reviews. Disease Primers

JF - Nature Reviews. Disease Primers

M1 - 16016

ER -

Atrial fibrillation

Abstract

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