Brain state-dependent peripheral nerve stimulation for plasticity induction in stroke patients

Research output: Contribution to book/anthology/report/conference proceedingArticle in proceedingResearchpeer-review

Abstract

Artificial activation of peripheral afferent fibers, with the resulting sensory feedback timed to arrive at the peak negativity of the movement-related cortical potential, induces significant increases in the excitability of cortical projections to the target muscle in healthy individuals and chronic stroke patients. In the currently ongoing study, we applied this associative brain- computer interface paradigm to sub-acute stroke patients. Compared to a sham group, where the peripheral electrical stimulation intensity was below the acti- vation threshold of the sensory afferents, the associative intervention group displayed substantial increases in corticospinal excitability to the target muscle (tibialis anterior).
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Artificial activation of peripheral afferent fibers, with the resulting sensory feedback timed to arrive at the peak negativity of the movement-related cortical potential, induces significant increases in the excitability of cortical projections to the target muscle in healthy individuals and chronic stroke patients. In the currently ongoing study, we applied this associative brain- computer interface paradigm to sub-acute stroke patients. Compared to a sham group, where the peripheral electrical stimulation intensity was below the acti- vation threshold of the sensory afferents, the associative intervention group displayed substantial increases in corticospinal excitability to the target muscle (tibialis anterior).
Original languageEnglish
Title of host publicationConverging Clinical and Engineering Research on Neurorehabilitation III : Proceedings of the 4th International Conference on NeuroRehabilitation (ICNR2018), October 16–20, 2018, Pisa, Italy
EditorsLorenzo Masia, Silvestro Micera, Metin Akay, José L. Pons
Number of pages5
PublisherSpringer
Publication date2019
Pages1066-1070
ISBN (Print) 978-3-030-01844
ISBN (Electronic)78-3-030-01845-0
DOI
Publication statusPublished - 2019
Publication categoryResearch
Peer-reviewedYes
EventInternational Conference on Neurorehabilitation - Pisa, Italy
Duration: 16 Oct 201820 Oct 2018
http://www.icnr2018.org

Conference

ConferenceInternational Conference on Neurorehabilitation
LandItaly
ByPisa
Periode16/10/201820/10/2018
Internetadresse
SeriesBiosystems and Biorobotics
Number21
ISSN2195-3562
ID: 288800549