Abstract
Notalgia paresthetica (NP) is a focal neuropathic itch con- dition manifesting in intense chronic or recurrent episodic itch in a hyperpigmented, macular, uni- or bilateral skin area located below and/or medially to the scapulae. Achieving satisfactory relieve in NP patients is challenging. In this case-series three female NP patients were treated with 8% capsaicin patches following a spatial quantification of their alloknetic area with a von Frey filament. The use of a von Frey filament in order to delimit the precise area of itch sensitiza- tion and thus patch application, proved clinically feasible. Although 8% topical capsaicin relieved itch in all three pa- tients, the duration of the effectiveness varied greatly from only 3 days to >2 months. The treatment was well tolerated in the patients and there appear to be no significant hin- drances to applying this treatment with NP as an indication, although it may only exhibit satisfactory effectiveness in cer- tain patients. Placebo-controlled double-blinded trials are needed to confirm the effectiveness of the treatment and as- sess predictive parameters of the treatment outcome
Original language | English |
---|---|
Journal | Annals of Dermatology |
Volume | 28 |
Issue number | 1 |
Pages (from-to) | 86-89 |
ISSN | 1013-9087 |
DOIs | |
Publication status | Published - 1 Feb 2016 |
Keywords
- Alloknesis
- Capsaicin
- Itch
- Neuropathic
- Notalgia paresthetica