Abstract
MicroRNAs (miRNAs) play key regulatory roles in diverse biological processes and are frequently dysregulated in human diseases. Thus, miRNAs have emerged as a class of promising targets for therapeutic intervention. Here, we describe the current strategies for therapeutic modulation of miRNAs and provide an update on the development of miRNA-based therapeutics for the treatment of cancer, cardiovascular disease and hepatitis C virus (HCV) infection.
Original language | English |
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Journal | E M B O Molecular Medicine (Online) |
Volume | 6 |
Issue number | 7 |
Pages (from-to) | 851-864 |
Number of pages | 14 |
ISSN | 1757-4676 |
DOIs | |
Publication status | Published - 2014 |