Prolonged outpatient vitamin K antagonist use and risk of venous thromboembolism in patients undergoing total hip or knee replacement

A Lalmohamed, P Vestergaard, P A F Jansen, E L Grove, A de Boer, H G M Leufkens, T P van Staa, F de Vries

Research output: Contribution to journalJournal articleResearchpeer-review

5 Citations (Scopus)

Abstract

Long-term risk of venous thromboembolism (VTE) following total hip or knee replacement (THR/TKR) compared with controls has not been studied extensively, and the long-term influence of outpatient anticoagulant use on VTE risk remains unknown. The objectives were to evaluate long-term VTE risk following THR/TKR compared with matched controls, and to investigate effect modification by prolonged outpatient vitamin K antagonist use.
Original languageEnglish
JournalJournal of Thrombosis and Haemostasis
Volume11
Issue number4
Pages (from-to)642-650
Number of pages9
ISSN1538-7933
DOIs
Publication statusPublished - Apr 2013

Keywords

  • Aged
  • Aged, 80 and over
  • Anticoagulants
  • Arthroplasty, Replacement, Hip
  • Arthroplasty, Replacement, Knee
  • Case-Control Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Outpatients
  • Retrospective Studies
  • Risk Factors
  • Venous Thromboembolism
  • Vitamin K

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