Long pacing Pulses Reduce Phrenic Nerve Stimulation in Left Ventricular Pacing

Søren Hjortshøj; Finn Peter Heath; Morten Haugland; Ole Eschen; Anna Margrethe Thøgersen; Sam Riahi; Egon Toft; Johannes Jan Struijk

doi:10.1111/jce.12345

Long pacing Pulses Reduce Phrenic Nerve Stimulation in Left Ventricular Pacing

Søren Hjortshøj, Finn Peter Heath, Morten Haugland, Ole Eschen, Anna Margrethe Thøgersen, Sam Riahi, Egon Toft, Johannes Jan Struijk

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Abstract

Phrenic nerve stimulation is a major obstacle in cardiac resynchronization therapy (CRT). Activation characteristics of the heart and phrenic nerve are different with higher chronaxie for the heart. Therefore, longer pulse durations could be beneficial in preventing phrenic nerve stimulation during CRT due to a decreased threshold for the heart compared to the phrenic nerve. We investigated if long pulse durations decreased left ventricular (LV) thresholds relatively to phrenic nerve thresholds in humans.

Original language	English
Journal	Journal of Cardiovascular Electrophysiology
Volume	25
Issue number	5
Pages (from-to)	485-490
Number of pages	6
ISSN	1045-3873
DOIs	https://doi.org/10.1111/jce.12345
Publication status	Published - 2014

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title = "Long pacing Pulses Reduce Phrenic Nerve Stimulation in Left Ventricular Pacing",

abstract = "Phrenic nerve stimulation is a major obstacle in cardiac resynchronization therapy (CRT). Activation characteristics of the heart and phrenic nerve are different with higher chronaxie for the heart. Therefore, longer pulse durations could be beneficial in preventing phrenic nerve stimulation during CRT due to a decreased threshold for the heart compared to the phrenic nerve. We investigated if long pulse durations decreased left ventricular (LV) thresholds relatively to phrenic nerve thresholds in humans.",

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AU - Hjortshøj, Søren

AU - Heath, Finn Peter

AU - Haugland, Morten

AU - Eschen, Ole

AU - Thøgersen, Anna Margrethe

AU - Riahi, Sam

AU - Toft, Egon

AU - Struijk, Johannes Jan

PY - 2014

Y1 - 2014

N2 - Phrenic nerve stimulation is a major obstacle in cardiac resynchronization therapy (CRT). Activation characteristics of the heart and phrenic nerve are different with higher chronaxie for the heart. Therefore, longer pulse durations could be beneficial in preventing phrenic nerve stimulation during CRT due to a decreased threshold for the heart compared to the phrenic nerve. We investigated if long pulse durations decreased left ventricular (LV) thresholds relatively to phrenic nerve thresholds in humans.

AB - Phrenic nerve stimulation is a major obstacle in cardiac resynchronization therapy (CRT). Activation characteristics of the heart and phrenic nerve are different with higher chronaxie for the heart. Therefore, longer pulse durations could be beneficial in preventing phrenic nerve stimulation during CRT due to a decreased threshold for the heart compared to the phrenic nerve. We investigated if long pulse durations decreased left ventricular (LV) thresholds relatively to phrenic nerve thresholds in humans.

U2 - 10.1111/jce.12345

DO - 10.1111/jce.12345

M3 - Journal article

C2 - 24329999

SN - 1045-3873

VL - 25

SP - 485

EP - 490

JO - Journal of Cardiovascular Electrophysiology

JF - Journal of Cardiovascular Electrophysiology

IS - 5

ER -

Long pacing Pulses Reduce Phrenic Nerve Stimulation in Left Ventricular Pacing

Abstract

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