Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Cross-Disorder Group of the Psychiatric Genomics Consortium

Research output: Contribution to journalJournal articleResearchpeer-review

2216 Citations (Scopus)

Abstract

Findings from family and twin studies suggest that genetic contributions to psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to identify specific variants underlying genetic effects shared between the five disorders in the Psychiatric Genomics Consortium: autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia.
Original languageEnglish
JournalLancet
Volume381
Issue number9875
Pages (from-to)1371-9
Number of pages9
ISSN0140-6736
DOIs
Publication statusPublished - 20 Apr 2013

Keywords

  • Adult
  • Age of Onset
  • Attention Deficit Disorder with Hyperactivity
  • Bipolar Disorder
  • Calcium Channels, L-Type
  • Child
  • Child Development Disorders, Pervasive
  • Depressive Disorder, Major
  • Genetic Loci
  • Genome-Wide Association Study
  • Humans
  • Logistic Models
  • Polymorphism, Single Nucleotide
  • Schizophrenia

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