Abstract
The neutrophil-lymphocyte ratio (NLR) is a novel biomarker, showing promising both diagnostic and prognostic capabilities. The aim of this study was to present NLR distributions in a Danish population from general practice (GP) and compare levels between patients from intensive care units (ICU) and GP. A register-based study was conducted using results from 31,966 blood samples from GP and ICU located in the admission area of Aarhus University Hospital, Denmark. Exclusion of samples with lymphocytes >40 × 10 9 /L, resulted in 28,582 samples from GP and 3,373 from ICU. Distributions for patients from GP with CRP <8 mg/L were age-dependent and were established for the following three age groups; 0–17 years [0.30:3.76], 18–75 years: [0.74:4.94], above 76 years: [0.89:8.80]. Patients from ICU had a significantly higher median NLR than patients from GP when stratified for CRP, [8.48 and 1.99 respectively]. This study describes for the first time the distributions of NLR in a large European population of GP patients.
Original language | English |
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Journal | Scandinavian Journal of Clinical & Laboratory Investigation |
Volume | 79 |
Issue number | 1-2 |
Pages (from-to) | 75–79 |
Number of pages | 5 |
ISSN | 0036-5513 |
DOIs | |
Publication status | Published - 15 Jan 2019 |
Keywords
- Adolescent
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- C-Reactive Protein/metabolism
- Child
- Child, Preschool
- Denmark
- Diagnostic Tests, Routine/methods
- European Continental Ancestry Group
- Female
- General Practice
- Humans
- Infant
- Infant, Newborn
- Intensive Care Units
- Leukocyte Count
- Lymphocytes/cytology
- Male
- Middle Aged
- Neutrophils/cytology
- Sex Factors