TY - GEN
T1 - The Efficacy of a Real-Time vs an Offline Associative Brain-Computer-Interface
AU - Mrachacz-Kersting, N.
AU - Aliakbaryhosseinabadi, S.
AU - Jiang, N.
AU - Farina, D.
PY - 2019
Y1 - 2019
N2 - An associative brain-computer-interface (BCI) that correlates a peripherally generated afferent volley with the peak negativity (PN) of the movement related cortical potential (MRCP) induces plastic changes in the human motor cortex. The aim of the current study was to compare the effectiveness of this intervention when the MRCP PN time is pre-determined from a training data set (BCIoffline), or detected online (BCIonline). Ten healthy participants completed both interventions in randomized order. The mean peak-to-peak motor evoked potential (MEP) amplitudes were significantly larger 30 min after (277 ± 72 µV) the BCI interventions compared to pre-intervention MEPs (233 ± 64 µV) regardless of intervention type and stimulation intensity (p = 0.029). These results provide further strong support for the associative nature of the associative BCI but also suggest that they likely differ to the associative long-term potentiation protocol they were modelled on in the exact sites of plasticity.
AB - An associative brain-computer-interface (BCI) that correlates a peripherally generated afferent volley with the peak negativity (PN) of the movement related cortical potential (MRCP) induces plastic changes in the human motor cortex. The aim of the current study was to compare the effectiveness of this intervention when the MRCP PN time is pre-determined from a training data set (BCIoffline), or detected online (BCIonline). Ten healthy participants completed both interventions in randomized order. The mean peak-to-peak motor evoked potential (MEP) amplitudes were significantly larger 30 min after (277 ± 72 µV) the BCI interventions compared to pre-intervention MEPs (233 ± 64 µV) regardless of intervention type and stimulation intensity (p = 0.029). These results provide further strong support for the associative nature of the associative BCI but also suggest that they likely differ to the associative long-term potentiation protocol they were modelled on in the exact sites of plasticity.
UR - http://www.scopus.com/inward/record.url?scp=85055326460&partnerID=8YFLogxK
U2 - 10.1007/978-3-030-01845-0_179
DO - 10.1007/978-3-030-01845-0_179
M3 - Article in proceeding
AN - SCOPUS:85055326460
SN - 978-3-030-01844-3
T3 - Biosystems and Biorobotics
SP - 893
EP - 896
BT - Converging Clinical and Engineering Research on Neurorehabilitation III
PB - Springer
T2 - 4th International Conference on NeuroRehabilitation, ICNR2018
Y2 - 16 October 2018 through 20 October 2018
ER -