Driven by the global competition, process Innovation has been a
challenge to large enterprises for many years. The research in this paper
discusses about the theory and methods of Business Process Innovation (BPI) in
designing Intelligent Supply Chains (ISC) in inter-organizations. We first
review the BPI concepts, compare it with Business Process Improvement
(BPIm) and Business Process Reengineering (BPR), and then build an
analytical framework to define business process innovation from four different
perspectives: management science, knowledge management, information
technology and quality control/process improvement. Then we present the case
study of Genpact, and based on the findings we formulate the challenges
towards a toolbox for a process innovation laboratory. These guidelines are the
main contributions of this paper.