Projekter pr. år
Organisationsprofil
Organisationsprofil
Head of research group:
Research group name
Genomic Medicine
Initials of research group
GM
Who we are?
The group members have a background in molecular medicine, computational biology, quantitative and statistical genetics with expertise within complex trait genetics, mathematical modelling, biostatistics, and machine learning.
Our research – what we do?
The Genomic Medicine research group is dedicated to leveraging large-scale genetics and genomics to investigate the phenotypic diversity in humans. Our mission focuses on pioneering the development of statistical genetic methods, implement machine learning algorithms, and integrate artificial intelligence to propel genetic research and precision medicine forward. We strive to create precision medicine tools and uncover novel causal mechanisms for multifactorial diseases.
How does our research contribute to societal health challenges?
By identifying the genetic causes, underlying molecular mechanisms, and developing molecular predictors and clinical decision support tools, our research contributes to increased equity in health and society.
Fingerprint
Samarbejde i de sidste fem år
Profiler
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LIGHTS: The Northern Lighthouse Predicting and Preventing Cardiometabolic Diseases
Larsen, T. K. (PI (principal investigator)), Rohde, P. D. (PI (principal investigator)), Hangaard, S. (PI (principal investigator)), Cichosz, S. L. (PI (principal investigator)) & Plocharski, M. (PI (principal investigator))
29/10/2025 → …
Projekter: Projekt › Forskning
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The Deadly, the Deleterious, and the Dangerous – Decoding the Differential Pathogenicity among CALM1, CALM2, and CALM3
Christiansen, S. N. N. (PI (principal investigator)), Nyegaard, M. (CoI (co-investigator)), Overgaard, M. T. (Andet), Schierup, M. H. (Andet), Tfelt-Hansen, J. (CoPI) & Schwartz, P. J. (Andet)
01/07/2024 → 30/06/2026
Projekter: Projekt › Forskning
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SURVIVE Unravelling endocrine mechanisms to improve maternal health and increase fetal survival
Rohde, P. D. (Projektdeltager) & Nyegaard, M. (CoI (co-investigator))
01/01/2023 → 31/12/2026
Projekter: Projekt › Forskning
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Sequence Diversity Lost in Early Pregnancy
Arnadottir, G. A., Johnsson, H., Schlaikjær Hartwig, T., Gruhn, J. R., Møller, P. L., Gylfason, A., Westergaard, D., Chi-Ho Chan, A., Oddsson, A., Stefansdottir, L., le Roux, L., Steinthorsdottir, V., Swerford Moore, K. H., Olafsson, S., Olason, P. I., Eggertsson, H. P., Halldórsson, G. H., Walters, G. B., Stefansson, H. & Gudjonsson, S. A. & 19 flere, , jan. 2026, I: Obstetrical & Gynecological Survey. 81, 1, s. 26-27 2 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Formidling
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A genome-wide association meta-analysis links hidradenitis suppurativa to common and rare sequence variants causing disruption of the Notch and Wnt/β-catenin signaling pathways
Andersen, R. K., Stefansdottir, L., Riis, P. T., Halldorsson, G., Ferkingstad, E., Oddsson, A., Walters, G. B., Olafsdottir, T. A., Rutsdottir, G., Zachariae, C., Thomsen, S. F., Brodersen, T., Dinh, K. M., Knowlton, K. U., Knight, S., Nadauld, L. D., Banasik, K., Brunak, S., Hansen, T. F. & Hjalgrim, H. & 23 flere, , apr. 2025, I: Journal of the American Academy of Dermatology. 92, 4, s. 761-772 12 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil9 Citationer (Scopus)46 Downloads (Pure) -
Associations between past infectious mononucleosis diagnosis and 47 inflammatory and vascular stress biomarkers
Kristjánsson, R. P., Dietz, J.B.-N., Davíðsson, Ó. B., Kjerulff, B., Rostgaard, K., Dowsett, J., Søegaard, S. H., Rotbain, E. C., Schwinn, M., Burgdorf, K. S., Bay, J. T., Mikkelsen, C., Ullum, H., Brunak, S., Sørensen, E., Jensen, B. A., Bruun, M. T., Nyegaard, M., Ostrowski, S. R. & Pedersen, O. B. & 3 flere, , 2 apr. 2025, I: Scientific Reports. 15, 1, 11312.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil17 Downloads (Pure)
Forskningsdatasæt
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Additional file 2 of Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease
Møller, P. L. (Ophavsperson), Rohde, P. D. (Ophavsperson), Dahl, J. N. (Ophavsperson), Rasmussen, L. D. (Ophavsperson), Nissen, L. (Ophavsperson), Schmidt, S. E. (Ophavsperson), McGilligan, V. (Ophavsperson), Gudbjartsson, D. F. (Ophavsperson), Stefansson, K. (Ophavsperson), Holm, H. (Ophavsperson), Bentzon, J. F. (Ophavsperson), Bøttcher, M. (Ophavsperson), Winther, S. (Ophavsperson) & Nyegaard, M. (Ophavsperson), Figshare, 15 aug. 2024
DOI: 10.6084/m9.figshare.25449091, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Predicting_the_presence_of_coronary_plaques_featuring_high-risk_characteristics_using_polygenic_risk_scores_and_targeted_proteomics_in_patients_with_suspected_coronary_artery_disease/25449091
Datasæt
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Additional file 2 of Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease
Møller, P. L. (Ophavsperson), Rohde, P. D. (Ophavsperson), Dahl, J. N. (Ophavsperson), Rasmussen, L. D. (Ophavsperson), Nissen, L. (Ophavsperson), Schmidt, S. E. (Ophavsperson), McGilligan, V. (Ophavsperson), Gudbjartsson, D. F. (Ophavsperson), Stefansson, K. (Ophavsperson), Holm, H. (Ophavsperson), Bentzon, J. F. (Ophavsperson), Bøttcher, M. (Ophavsperson), Winther, S. (Ophavsperson) & Nyegaard, M. (Ophavsperson), Figshare, 15 aug. 2024
DOI: 10.6084/m9.figshare.25449091.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Predicting_the_presence_of_coronary_plaques_featuring_high-risk_characteristics_using_polygenic_risk_scores_and_targeted_proteomics_in_patients_with_suspected_coronary_artery_disease/25449091/1
Datasæt
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Data from: The Drosophila Genetic Reference Panel (DGRP) on locomotor activity across different environmental conditions
Krog Noe, N. (Ophavsperson), Duun Rohde, P. (Ophavsperson), Sørensen, P. (Ophavsperson) & Nygaard Kristensen, T. (Ophavsperson), Dryad, 14 feb. 2024
DOI: 10.5061/dryad.fxpnvx10n, https://datadryad.org/dataset/doi:10.5061/dryad.fxpnvx10n
Datasæt
Aktiviteter
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From Integrative Genomics to Polygenic Risk Scoring
Sørensen, P. (Foredragsholder) & Rohde, P. D. (Foredragsholder)
27 okt. 2025Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
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Prediction of high-risk plaques in coronary heart disease using genetics and targeted proteomics
Rohde, P. D. (Foredragsholder)
3 nov. 2022Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
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Medlem af bedømmelsesudvalg PhD Anne Krogh Nøhr (Begivenhed)
Nyegaard, M. (Forperson)
1 jul. 2022Aktivitet: Medlemskab › Medlemskab af bedømmelsesudvalg
Presse/medier
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Hun stod bag tv-dokumentar om vildt rets-drama: Nu har hun skrevet bog om forløbet
Nyegaard, M. & Overgaard, M. T.
22/01/2026
1 element af Mediedækning
Presse/medie
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Det skal du glæde dig til på årets Life Science Meetup
18/08/2025
1 element af Mediedækning
Presse/medie
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Debat: Danmark skal have et nationalt videnscenter for kvinders sundhed
04/06/2025 → 27/06/2025
2 Mediebidrag
Presse/medie
Impacts
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Forskning i genfejl kan benåde australsk kvinde
Jensen, H. H. (Deltager), Brohus, M. B. (Deltager), Overgaard, M. T. (Deltager) & Nyegaard, M. (Deltager)
Impact: Social impact