• Fredrik Bajers Vej 3B

    DK-9220 Aalborg Øst

    Danmark

Publikationer 2007 2019

2019

A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response

Gudbergsson, J. M., Kostrikov, S., Johnsen, K. B., Fliedner, F. P., Stolberg, C. B., Humle, N., Hansen, A. E., Kristensen, B. W., Christiansen, G., Kjær, A., Andresen, T. L. & Duroux, M., 1 jun. 2019, I : Experimental Cell Research. 379, 1, s. 73-82 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Glioblastoma
Pharmaceutical Preparations
Nestin
oxaliplatin
Vimentin

DNA methylation regulates CHRNA7 transcription and can be modulated by valproate

Dyrvig, M., Mikkelsen, J. D. & Lichota, J., 21 jun. 2019, I : Neuroscience Letters. 704, s. 145-152 8 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Valproic Acid
DNA Methylation
Epigenomics
Nicotinic Receptors
Schizophrenia
4 Citationer (Scopus)

Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo

Johnsen, K. B., Bak, M., Melander, F., Thomsen, M. S., Burkhart, A., Kempen, P. J., Andresen, T. L. & Moos, T., 8 jan. 2019, I : Journal of Controlled Release.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Transferrin Receptors
Blood-Brain Barrier
Gold
Nanoparticles
Antibodies
2018
8 Citationer (Scopus)
516 Downloads (Pure)

Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles

Johnsen, K. B., Bak, M., Kempen, P. J., Melander, F., Burkhart, A., Thomsen, M. S., Nielsen, M. S., Moos, T. & Andresen, T. L., 2018, I : Theranostics. 8, 12, s. 3416-3436

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Transferrin Receptors
Antibody Affinity
Gold
Nanoparticles
Nanomedicine

Drug delivery to the brain: How to overcome the blood-brain barrier?

Thomsen, L. B., jan. 2018, I : Journal of Self-Assembly and Molecular Electronics. 6, Suppl. 1, s. 1-1 1 s., 4.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Åben adgang
1 Citation (Scopus)
Hepcidins
PC12 Cells
Iron
Messenger RNA
Deferoxamine
1 Citation (Scopus)
2 Downloads (Pure)

Intravenous iron isomaltoside improves hemoglobin concentration and iron stores in female iron-deficient blood donors: a randomized double-blind placebo-controlled clinical trial

Gybel-Brask, M., Seeberg, J., Thomsen, L. L. & Johansson, P. I., 1 apr. 2018, I : Transfusion. 58, 4, s. 974-981 8 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Controlled Clinical Trials
Blood Donors
Hemoglobins
Iron
Placebos
3 Citationer (Scopus)
50 Downloads (Pure)

Iron deficiency and iron treatment in the fetal developing brain: a pilot study introducing an experimental rat model

Moos, T., Skjørringe, T. & Thomsen, L. L., 22 jun. 2018, I : Reproductive Health. 15, Suppl. 1, s. 117-120 93.

Publikation: Bidrag til tidsskriftKonferenceartikel i tidsskriftForskningpeer review

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Theoretical Models
Iron
Brain
Therapeutics
Mothers

MicroRNAs expression as circulating genomic biomarkers in patients with chronic postoperative pain after total knee replacement

Giordano, R., Petersen, K. K., Andersen, H. H., Lichota, J., Simonsen, O. & Arendt-Nielsen, L., 2018.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

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9 Citationer (Scopus)

On the use of liposome controls in studies investigating the clinical potential of extracellular vesicle-based drug delivery systems: A commentary

Johnsen, K. B., Gudbergsson, J. M., Duroux, M., Moos, T., Andresen, T. L. & Simonsen, J. B., 2018, I : Journal of Controlled Release. 269, s. 10-14

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

Drug Delivery Systems
Liposomes
Nanoparticles
Pharmaceutical Preparations
Therapeutic Uses
4 Citationer (Scopus)

The endo-lysosomal system of brain endothelial cells is influenced by astrocytes in vitro

Toth, A. E., Siupka, P., P Augustine, T. J., Venø, S. T., Thomsen, L. B., Moos, T., Lohi, H. T., Madsen, P., Lykke-Hartmann, K. & Nielsen, M. S., nov. 2018, I : Molecular Neurobiology. 55, 11, s. 8522-8537 16 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Astrocytes
Endothelial Cells
Brain
Blood-Brain Barrier
Transcytosis
2017
9 Citationer (Scopus)

Bidirectional apical-basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells

Siupka, P., Hersom, M. N. S., Lykke-Hartmann, K., Johnsen, K. B., Thomsen, L. B., Andresen, T. L., Moos, T., Abbott, N. J., Brodin, B. & Nielsen, M. S., 2017, I : Journal of Cerebral Blood Flow and Metabolism. 37, 7, s. 2598–2613

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

IGF Type 2 Receptor
Cations
Endothelial Cells
Brain
Transferrin Receptors
2 Citationer (Scopus)
50 Downloads (Pure)

Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease

Skjørringe, T., Pedersen, P. A., Thorborg, S. S., Nissen, P., Gourdon, P. & Møller, L. B., 1 dec. 2017, I : Scientific Reports. 7, 1, 18 s., 757.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Menkes Kinky Hair Syndrome
trans-Golgi Network
Copper
Mutation
Yeasts
5 Citationer (Scopus)
127 Downloads (Pure)

DNA methylation analysis of BRD1 promoter regions and the schizophrenia rs138880 risk allele

Dyrvig, M., Qvist, P., Lichota, J., Larsen, K., Nyegaard, M., Børglum, A. D. & Christensen, J. H., 2017, I : PLOS ONE. 12, 1, 19 s., e0170121.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Fil
DNA methylation
DNA Methylation
Genetic Promoter Regions
Schizophrenia
Alleles
12 Citationer (Scopus)
Endothelial cells
Pericytes
Blood-Brain Barrier
Basement Membrane
Brain
30 Citationer (Scopus)
30 Downloads (Pure)

Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

Johnsen, K. B., Burkhart, A., Melander, F., Kempen, P. J., Vejlebo, J. B., Siupka, P., Nielsen, M. S., Andresen, T. L. & Moos, T., 1 dec. 2017, I : Scientific Reports. 7, 13 s., 10396.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Fil
Transferrin Receptors
Blood-Brain Barrier
Brain
Endothelium
Transcytosis
10 Citationer (Scopus)
123 Downloads (Pure)

The choroid plexus as a site of damage in hemorrhagic and ischemic stroke and its role in responding to injury

Xiang, J., Routhe, L. J., Andrew Wilkinson, D., Hua, Y., Moos, T., Xi, G. & Keep, R. F., 28 mar. 2017, I : Fluids and Barriers of the CNS. 14, 13 s., 8.

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

Åben adgang
Fil
Choroid Plexus
Stroke
Wounds and Injuries
Hemorrhage
Cerebral Hemorrhage
5 Citationer (Scopus)

The schizophrenia-associated BRD1 gene regulates behavior, neurotransmission, and expression of schizophrenia risk enriched gene sets in mice

Qvist, P., Christensen, J. H., Vardya, I., Rajkumar, A. P., Mørk, A., Paternoster, V., Füchtbauer, E-M., Pallesen, J., Fryland, T., Dyrvig, M., Hauberg, M. E., Lundsberg, B., Fejgin, K., Nyegaard, M., Jensen, K., Nyengaard, J. R., Mors, O., Didriksen, M. & Børglum, A. D., 2017, I : Biological Psychiatry. 82, 1, s. 62-76

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Synaptic Transmission
Schizophrenia
Genes
Corpus Striatum
Chromatin
26 Citationer (Scopus)

The vascular basement membrane in the healthy and pathological brain

Thomsen, M. S., Routhe, L. J. & Moos, T., okt. 2017, I : Journal of Cerebral Blood Flow and Metabolism. 37, 10, s. 3300-3317

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

Basement Membrane
Blood Vessels
Brain
Pericytes
Endothelial Cells
1 Citation (Scopus)
Erythropoietin
Transfection
Endothelial Cells
Brain
Proteins
2016

A triple co-culture model of the blood-brain barrier using primary porcine brain endothelial cells, porcine pericytes and porcine astrocytes

Thomsen, L. B., Larsen, A. B. & Moos, T., 2016, IPC nr. C12N 5/071 (2010.01), C12N 5/079 (2010.01), G01N 33/50 (2006.01), Patentnr. WO/2016/202343 , 22 dec. 2016, Prioritetsdato 16 jun. 2016, Prioritetsnr. PCT/DK2016/050190

Publikation: PatentForskning

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Behandlingen af Alzheimers sygdom: det er vanskeligt at forstå, hvordan passiv immunterapi virker

Moos, T. & Thomsen, M. S., 2016, I : Ugeskrift for Laeger. 178, 15, s. 1457

Publikation: Bidrag til tidsskriftKommentar/debatForskning

Differential methylation of promoter regions and the schizophrenia rs138880 risk allele affects expression of BRD1

Christensen, J. H., Dyrvig, M., Qvist, P., Lichota, J., Larsen, K., Nyegaard, M. & Børglum, A. D., 2016.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

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Epigenetic regulation of human nicotinic acetylcholine receptor gene promoter

Lichota, J., Dyrvig, M. & Mikkelsen, J. D., 2016, 46th Annual Meeting of the Society for Neuroscience, Neuroscience 2016, 12-16 November 2016, San Diego, CA, USA. Society for Neuroscience, 650.15 / NNN36

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

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15 Citationer (Scopus)

Evaluation of electroporation-induced adverse effects on adipose-derived stem cell exosomes

Johnsen, K. B., Gudbergsson, J. M., Skov, M. N., Christiansen, G., Gurevich, L., Moos, T. & Duroux, M., 2016, I : Cytotechnology. 68, 5, s. 2125–2138

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Exosomes
Electroporation
Stem Cells
Glioblastoma
Pharmaceutical Preparations

Expression and deposition of basement membrane proteins by brain capillary endothelial cells in a primary murine model of the blood-brain barrier

Thomsen, M. S., Birkelund, S., Larsen, A. B., Stensballe, A. & Moos, T., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 37 P-12

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

21 Citationer (Scopus)

Expression of iron-related proteins at the neurovascular unit supports reduction and reoxidation of iron for transport through the blood-brain barrier

Burkhart, A., Skjørringe, T., Johnsen, K. B., Siupka, P., Thomsen, L. B., Nielsen, M. S., Thomsen, L. L. & Moos, T., 2016, I : Molecular Neurobiology. 53, 10, s. 7237-7253

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Blood-Brain Barrier
Iron
Ceruloplasmin
Brain
Endothelial Cells

Gene delivery of the therapeutic polypeptide erythropoietin to primary brain capillary endothelial cells for protein secretion

Larsen, A. B. & Moos, T., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 25 O-5

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

4 Citationer (Scopus)
97 Downloads (Pure)

Geographical variation in antipsychotic drug use in elderly patients with dementia: a nationwide study

Zakarias, J. K., Jensen-Dahm, C., Nørgaard, A., Stevnsborg, L., Gasse, C., Andersen, B. G., Søren, J., Waldorff, F. B., Moos, T. & Waldemar, G., 2016, I : Journal of Alzheimer's Disease. 54, 3, s. 1183-1192

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Fil
Antipsychotic Agents
Dementia
Denmark
Behavioral Symptoms
Caregivers
91 Downloads (Pure)

Metal-dependent regulation of ATP7A and ATP7B in fibroblast cultures

Lenartowicz, M., Moos, T., Ogórek, M., Jensen, T. G. & Møller, L. B., 2016, I : Frontiers in Molecular Neuroscience. 9, 68.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Fil
Copper
Fibroblasts
Metals
Menkes Kinky Hair Syndrome
Hepatolenticular Degeneration
30 Downloads (Pure)

On the prospect of clinical utilization of microRNAs as biomarkers or treatment of chronic pain

Andersen, H. H., Johnsen, K. B. & Arendt-Nielsen, L., 2016, I : Experimental Neurology. 284, Part A, s. 63-66

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Fil

Proteomics-driven design of endothelial stress-based protein array for disease prognostics: applied to plasma and cerebrospinal fluid

Kastaniegaard, K., Jørgensen, M. M., Bæk, R., Sejrbæk, T., Wiwie, C., Baumbach, J., Zachar, V., Moos, T., Nielsen, S., Nieland, J. D., Cotton, F., Guttmann, C., Illes, Z. & Stensballe, A., 2016, I : Journal of Extracellular Vesicles. 5, Suppl. 1, s. 4 1 s., OW2.2.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

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35 Citationer (Scopus)

Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier

Moos, T., Routhe, L. J., Birkelund, S., Burkhart, A., Stensballe, A. & Thomsen, M. S., 2016, 46th Annual Meeting of the Society for Neuroscience, Neuroscience 2016, 12-16 November 2016, San Diego, CA, USA. Society for Neuroscience, 140.10 / U1

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

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28 Citationer (Scopus)

Systematic review of factors influencing extracellular vesicle yield from cell cultures

Gudbergsson, J. M., Johnsen, K. B., Skov, M. N. & Duroux, M., 2016, I : Cytotechnology. 68, 4, s. 579-592

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

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6 Citationer (Scopus)

Targeted vascular drug delivery in cerebral cancer

Humle, N., Johnsen, K. B., Arendt, G. A., Nielsen, R. P., Moos, T. & Thomsen, L. B., 2016, I : Current Pharmaceutical Design. 22, 35, s. 5487-5504

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

Glioblastoma
Blood Vessels
Pharmaceutical Preparations
Neoplasms
Brain Neoplasms

Targeting immunoliposomes to transferrin receptors on brain capillary endothelial cells as a mean for cargo transport across the blood-brain barrier

Moos, T., Johnsen, K. B., Burkhart, A., Bruun, J., Siupka, P., Nielsen, M. S. & Andresen, T., 2016, 46th Annual Meeting of the Society for Neuroscience, Neuroscience 2016, 12-16 November 2016, San Diego, CA, USA. Society for Neuroscience, 140.13 / U4

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

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Targeting immunoliposomes to transferrin receptors on brain capillary endothelial cells as a mean for cargo transport across the blood-brain barrier

Johnsen, K. B., Larsen, A. B., Bruun, J., Siupka, P., Nielsen, M. S., Andresen, T. L. & Moos, T., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 51 P-51

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

Trafficking of Transferrin Receptor in primary porcine brain endothelial cells and its implication for drug delivery to the brain

Siupka, P., Thomsen, L. B., Lykke-Hartmann, K., Moos, T. & Nielsen, M. S., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 27 O-9

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

Vesicular transport in brain microvascular endothelial cells

Toth, A., Siupka, P., Pulikotial, A. T., Thomsen, L. B., Lohi, H. T., Lykke-Hartmann, K., Moos, T., Madsen, P. & Nielsen, M. S., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 42-43 P-29

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

2015

A novel transgenic mouse line co-expressing alpha-synuclein and p25alpha displays increased oligomer formation

Lassen, L. B., Jensen, P. H., Betzer, C. & Moos, T., 2015, 45th Annual Meeting of the Society for Neuroscience, Neuroscience 2015, 17-21 October 2015, Chicago, IL, USA. Society for Neuroscience, s. No. 647.10

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

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46 Citationer (Scopus)
188 Downloads (Pure)

A triple culture model of the blood-brain barrier using porcine brain endothelial cells, astrocytes and pericytes

Thomsen, L. B., Burkhart, A. & Moos, T., 2015, I : PLOS ONE. 10, 8, 16 s., e0134765.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Pericytes
blood-brain barrier
astrocytes
Endothelial cells
Blood-Brain Barrier
314 Downloads (Pure)
Åben adgang
Fil
46 Citationer (Scopus)
177 Downloads (Pure)
Åben adgang
Fil
10 Citationer (Scopus)

Epigenetic regulation of Dnmt3a and Arc gene expression after electroconvulsive stimulation in the rat

Dyrvig, M., Gøtzsche, C. R., Woldbye, D. P. D. & Lichota, J., 2015, I : Molecular and Cellular Neuroscience. 67, s. 137-143

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

decitabine
Epigenomics
Methylation
Gene Expression
DNA Methylation
3 Citationer (Scopus)

Handling iron in restorative neuroscience

Routhe, L. J. & Moos, T., 2015, I : Neural Regeneration Research. 10, 10, s. 1558-1559

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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21 Citationer (Scopus)

Neurodegeneration with inflammation is accompanied by accumulation of iron and ferritin in microglia and neurons

Thomsen, M. S., Andersen, M. V., Christoffersen, P. R., Jensen, M. D., Lichota, J. & Moos, T., 2015, I : Neurobiology of Disease. 81, s. 108-118

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Repercussions of glioblastoma multiforme on the blood-brain barrier

Humle, N. H., Thomsen, L. B. & Moos, T., 2015, I : Clinical Neuropathology. 34, 3, s. 149

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

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22 Citationer (Scopus)

Targeted drug delivery to the brain using magnetic nanoparticles

Thomsen, L. B., Thomsen, M. S. & Moos, T., 2015, I : Therapeutic Delivery. 6, 10, s. 1145-1155

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Nanoparticles
Blood-Brain Barrier
Endothelial Cells
Brain
Pharmaceutical Preparations