Projekter pr. år
Organisationsprofil
Organisationsprofil
Head of research group: Vladimir Zachar
Who we are?
The main theme of our research is investigation of stem cells, replacement tissues, and probiotics in order to harness their regenerative potential and synergies with the ultimate goal of developing novel therapeutic approaches.
Our research – what we do?
Our research focuses on the development of innovative interdisciplinary approaches to control the fate of stem cells and devise original clinically applicable cell- and tissue-based products. Major efforts are currently directed towards these areas:
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Use of adipose-derived stem cells in the treatment of chronic wounds, and bone and cartilage reconstruction
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Cell-based treatment of limbal stem cell deficiency
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Engineering of muscle tissue
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Probiotic Research Initiative: Application of probiotics in disease management and tissue regeneration
How does our research contribute to societal health challenges?
The group is involved in the translational research into novel regenerative therapies based on the use of probiotics, stem cells, and tissue engineering.
Who are our key collaborators?
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Prof. Hjortdal, Eye clinic, Aarhus University
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Prof. Kastrup, The heart center, Copenhagen University
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Prof. Ingersle v, Prof. Kesmodel, Fertility clinic and center for preimplantation diagnostic, Aalborg University Hospital
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Prof. Starch-Jensen, Dpt. of maxillary surgery, Aalborg University Hospital
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Assoc. Prof. Rasmussen, Dpt. of orthopedic surgery, Aalborg University Hospital
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Ass. Prof. Dolatshahi-Pirouz, DTU, Copenhagen
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Deerland Probiotics & Enzymes
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Innosurge
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Samarbejde i de sidste fem år
Profiler
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Supporting university student proactivity for social and academic well-being: What PBL can do
Chen, J. (PI (principal investigator)), Hansen, S. (PI (principal investigator)), Velmurugan, G. (PI (principal investigator)), Fink, T. (PI (principal investigator)), Lyngdorf, N. E. (CoI (co-investigator)), Søndergaard, B. D. (CoI (co-investigator)), Markman, A. O. (PI (principal investigator)), Guerra, A. (CoI (co-investigator)), Du, X. (CoI (co-investigator)), Stegeager, N. (CoI (co-investigator)) & Telléus, P. K. (CoI (co-investigator))
01/01/2025 → 31/12/2025
Projekter: Projekt › Forskning
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Development of cell-free therapy for chronic wound
Peng, Q. (PI (principal investigator)), Fink, T. (Projektdeltager) & Qian, Y. (Projektdeltager)
Leo Nielsen og Hustru Karen Margrethe Nielsens Legat for Lægevidenskabelig Grundforskning
01/09/2024 → 31/08/2025
Projekter: Projekt › Forskning
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PULSE: Precise understanding of vascular smooth muscle disease through advanced 3D-printed models
Pennisi, P. (PI (principal investigator)), Zachar, V. (CoPI) & Gao, F. (Projektdeltager)
01/11/2023 → 31/10/2026
Projekter: Projekt › Forskning
Publikationer
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Beyond autonomy: unpacking self-regulated and self-directed learning through the lens of learner agency- a scoping review
Gupta, N., Ali, K., Jiang, D., Fink, T. & Du, X., 23 dec. 2024, I: BMC Medical Education. 24, 1, s. 12 12 s., 1519.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil3 Downloads (Pure) -
Challenges in the processing and preservation of adipose-derived stem cell subpopulations for clinical use
Peng, Q., dec. 2024, I: Regenerative Medicine. 19, 12, s. 595-597 3 s.Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review
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Chitosan nanoparticle encapsulation improves the effect of donepezil on impaired memory in an amnesia mouse model
Heidari, M., Azami, N., Ebadi, M., Dardmeh, F., Sepahi Charmi, S. & Alipour, H., 13 nov. 2024, I: Discover Medicine. 1, 109.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil
Forskningsdatasæt
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Data for research article titled: "Lactobacillus rhamnosus PB01 (DSM 14870) supplementation affects markers of sperm kinematic parameters in a diet-induced obesity mice model"
Dardmeh, F. (Ophavsperson), Alipour, H. (Bidrager), Gazerani, P. (Ophavsperson), Van Der Horst, G. (Bidrager), Brandsborg, E. (Ophavsperson) & Nielsen, H. I. (Ophavsperson), Figshare, 27 sep. 2017
DOI: 10.6084/m9.figshare.5446525.v1, https://figshare.com/articles/dataset/Data_for_research_article_titled_Lactobacillus_rhamnosus_PB01_DSM_14870_supplementation_affects_markers_of_sperm_kinematic_parameters_in_a_diet-induced_obesity_mice_model_/5446525/1
Datasæt
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Maintaining RNA Integrity for Transcriptomic Profiling of Ex Vivo Cultured Limbal Epithelial Stem Cells after Fluorescence-Activated Cell Sorting (FACS)
Liu, L. (Ophavsperson), Nielsen, F. M. (Ophavsperson), Riis, S. E. (Ophavsperson), Emmersen, J. (Ophavsperson), Fink, T. (Ophavsperson), Hjortdal, J. Ø. (Ophavsperson), Bath, C. (Ophavsperson) & Zachar, V. (Ophavsperson), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3952822, https://figshare.com/collections/Maintaining_RNA_Integrity_for_Transcriptomic_Profiling_of_Ex_Vivo_Cultured_Limbal_Epithelial_Stem_Cells_after_Fluorescence-Activated_Cell_Sorting_FACS_/3952822
Datasæt
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Additional file 1: of Maintaining RNA Integrity for Transcriptomic Profiling of Ex Vivo Cultured Limbal Epithelial Stem Cells after Fluorescence-Activated Cell Sorting (FACS)
Liu, L. (Ophavsperson), Nielsen, F. M. (Ophavsperson), Riis, S. E. (Ophavsperson), Emmersen, J. (Ophavsperson), Fink, T. (Ophavsperson), Hjortdal, J. Ø. (Ophavsperson), Bath, C. (Ophavsperson) & Zachar, V. (Ophavsperson), Figshare, 2017
DOI: 10.6084/m9.figshare.5696704.v1, https://doi.org/10.6084%2Fm9.figshare.5696704.v1
Datasæt
Aktiviteter
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From Gametes to Embryos: Navigating the Complexities of Reproduction
Alipour, H. (Foredragsholder)
8 nov. 2024Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
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Characterization of antibodies and their influence on internalization of Chlamydia trachomatis into host cells
Pennisi, P. (Eksaminator)
9 feb. 2024Aktivitet: Ph.d.-vejledning, censoraktivitet og eksaminering › Intern censoraktivitet/eksaminering
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Studies for Regenerative Medicine for Vaginal Reconstructive Surgery
Pennisi, P. (Opponent)
19 jan. 2024Aktivitet: Ph.d.-vejledning, censoraktivitet og eksaminering › Ekstern censoraktivitet
Presse/medier
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Debat: Kampen om lægestuderendes læring
Andersen, L. S., Emmersen, J. & Kristensen, J. K.
03/04/2023
1 Mediebidrag
Presse/medie