• Fredrik Bajers Vej 3, B, 1-209

    9220 Aalborg Ø

    Danmark

20022019
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Publikationer 2002 2019

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Tidsskriftartikel
2019

Fabrication and characterization of extracellular matrix scaffolds obtained from adipose-derived stem cells

Riis, S., Hansen, A. C., Johansen, L., Lund, K., Pedersen, C., Pitsa, A., Hyldig, K., Zachar, V., Fink, T. & Pennisi, C. P., 9 jul. 2019, I : Methods.

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Stem cells
Scaffolds
Extracellular Matrix
Stem Cells
Wound Healing
2018
2 Citationer (Scopus)

Focal adhesion kinase activation is necessary for stretch-induced alignment and enhanced differentiation of myogenic precursor cells

Andersen, J. I., Pennisi, C. P., Fink, T. & Zachar, V., 1 apr. 2018, I : Tissue Engineering. Part A. 24, 7-8, s. 631-640 10 s.

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Focal Adhesion Protein-Tyrosine Kinases
Adhesion
Chemical activation
Tensile strain
Myoblasts
3 Citationer (Scopus)
112 Downloads (Pure)

Hypoxia enhances differentiation of adipose tissue-derived stem cells toward the smooth muscle phenotype

Wang, F., Zachar, V., Pennisi, C. P., Fink, T., Maeda, Y. & Emmersen, J., 2018, I : International Journal of Molecular Sciences . 19, 2, 12 s., 517.

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adipose tissues
smooth muscle
phenotype
stem cells
hypoxia
2 Citationer (Scopus)
72 Downloads (Pure)

Pigmentation is associated with stemness hierarchy of progenitor cells within cultured limbal epithelial cells

Liu, L., Nielsen, F. M., Emmersen, J., Bath, C., Hjortdal, J. Ø., Riis, S., Fink, T., Pennisi, C. P. & Zachar, V., sep. 2018, I : Stem Cells. 36, 9, s. 1411-1420 10 s.

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Pigmentation
Stem Cells
Epithelial Cells
Adenosine Triphosphate
Keratin-3

Regeneration of the oesophageal muscle layer from oesophagus acellular matrix scaffold using adipose-derived stem cells

Wang, F., Maeda, Y., Zachar, V., Ansari, T. & Emmersen, J., 3 sep. 2018, I : Biochemical and Biophysical Research Communications. 503, 1, s. 271-277 7 s.

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Stem cells
Scaffolds
Esophagus
Muscle
Regeneration
2017
6 Citationer (Scopus)
168 Downloads (Pure)

Hypoxia enhances the wound-healing potential of adipose-derived stem cells in a novel human primary keratinocyte-based scratch assay

Riis, S., Newman, R., Ipek, H., Andersen, J. I., Kuninger, D., Boucher, S., Vemuri, M. C., Pennisi, C. P., Zachar, V. & Fink, T., 2017, I : International Journal of Molecular Medicine. 39, 3, s. 587-594

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Keratinocytes
Wound Healing
Stem Cells
Calcium
Conditioned Culture Medium
2 Citationer (Scopus)
214 Downloads (Pure)

Maintaining RNA integrity for transcriptomic profiling of ex vivo cultured limbal epithelial stem cells after fluorescence-activated cell sorting (FACS)

Liu, L., Nielsen, F. M., Riis, S. E., Emmersen, J., Fink, T., Hjortdal, J. Ø., Bath, C. & Zachar, V., 12 dec. 2017, I : Biological Procedures Online. 19, 7 s., 15.

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Stem cells
Sorting
Flow Cytometry
Stem Cells
Epithelial Cells
2016
18 Citationer (Scopus)
185 Downloads (Pure)

Boron-doped nanocrystalline diamond electrodes for neural interfaces: in vivo biocompatibility evaluation

Alcaide, M., Taylor, A., Fjorback, M., Zachar, V. & Pennisi, C. P., 2016, I : Frontiers in Neuroscience. 10, 9 s., 87.

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Diamond
Boron
Electrodes
Implanted Electrodes
Capsules
17 Citationer (Scopus)

Comparative analysis of media and supplements on initiation and expansion of adipose-derived stem cells

Riis, S., Nielsen, F. M., Pennisi, C. P., Zachar, V. & Fink, T., 2016, I : Stem Cells Translational Medicine. 5, 3, s. 314-324

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Stem Cells
Blood Platelets
Serum
Eagles
Serum-Free Culture Media
3 Citationer (Scopus)
179 Downloads (Pure)

Discrete adipose-derived stem cell subpopulations may display differential functionality after in vitro expansion despite convergence to a common phenotype distribution

Nielsen, F. M., Riis, S. E., Andersen, J. I., Lesage, R., Fink, T., Pennisi, C. P. & Zachar, V., 2016, I : Stem Cell Research & Therapy. 7, 13 s., 177.

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Stem cells
Stem Cells
Phenotype
Flow cytometry
Wound Healing
18 Citationer (Scopus)
287 Downloads (Pure)
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Fil
7 Citationer (Scopus)

Resistance to protein adsorption and adhesion of fibroblasts on nanocrystalline diamond films: the role of topography and boron doping

Alcaide, M., Papaioannou, S., Taylor, A., Fekete, L., Gurevich, L., Zachar, V. & Pennisi, C. P., 2016, I : Journal of Materials Science: Materials in Medicine. 27, 5, 12 s., 90.

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Diamond
Boron
Diamond films
Fibroblasts
Topography
2015
4 Citationer (Scopus)
252 Downloads (Pure)

Synthesis of nano- and micro-scale topographies by combining colloidal lithography and glancing angle deposition (GLAD)

Dolatshahi-Pirouz, A., Kolind, K., Pennisi, C. P., Duroux, M., Zachar, V., Foss, M. & Besenbacher, F., 2015, I : Advanced Engineering Materials. 17, 1, s. 8-13

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2014
37 Citationer (Scopus)

Comparison of human adipose-derived stem cells and bone marrow-derived stem cells in a myocardial infarction model

Rasmussen, J., Frøbert, O., Holst-Hansen, C., Kastrup, J., Baandrup, U., Zachar, V., Fink, T. & Simonsen, U., 2014, I : Cell Transplantation. 23, 2, s. 195-206

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13 Citationer (Scopus)

Cripto-1 expression in glioblastoma multiforme

Pilgaard, L., Mortensen, J. H., Henriksen, M., Olesen, P., Sørensen, P., Laursen, R. J., Vyberg, M., Agger, R., Zachar, V., Moos, T. & Duroux, M., 2014, I : Brain Pathology. 24, 4, s. 360–370

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13 Citationer (Scopus)

Hypoxia enhances chondrogenic differentiation of human adipose tissue-derived stromal cells in scaffold-free and scaffold systems

Munir, S., Foldager, C. B., Lind, M., Zachar, V., Søballe, K. & Koch, T. G., 2014, I : Cell and Tissue Research. 355, 1, s. 89-102

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6 Citationer (Scopus)

Moderate hypoxia influences potassium outward currents in adipose-derived stem cells

Prasad, M. S., Zachar, V., Fink, T. & Pennisi, C. P., 2014, I : P L o S One. 9, 8, 10 s., e104912.

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2 Citationer (Scopus)

Technical brief: Optimized pipeline for isolation of high-quality RNA from corneal cell subpopulations

Søndergaard, C. B., Fink, T., Vorum, H., Hjortdal, J. & Zachar, V., 2014, I : Molecular Vision. 20, s. 797-803

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11 Citationer (Scopus)

Uniaxial cyclic strain enhances adipose-derived stem cell fusion with skeletal myocytes

Andersen, J. I., Juhl, M., Nielsen, T., Emmersen, J., Fink, T., Zachar, V. & Pennisi, C. P., 2014, I : Biochemical and Biophysical Research Communications. 450, 2, s. 1083-1088

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2013
27 Citationer (Scopus)

Development of cardiac support bioprostheses for ventricular restoration and myocardial regeneration

Shafy, A., Fink, T., Zachar, V., Lila, N., Carpentier, A. & Chachques, J. C., 2013, I : European Journal of Cardio-Thoracic Surgery. 43, 6, s. 1211-1219

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2 Citationer (Scopus)

Elliptical posts allow for detailed control of non-equibiaxial straining of cell cultures

Olesen, C. G., Pennisi, C. P., de Zee, M., Zachar, V. & Rasmussen, J., maj 2013, I : Journal of Tissue Viability. 22, 2, s. 52-56 5 s.

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15 Citationer (Scopus)

Hypoxia is a key regulator of limbal epithelial stem cell growth and differentiation

Søndergaard, C. B., Yang, S., Muttuvelu, D. V., Fink, T., Emmersen, J., Vorum, H., Hjortdal, J. Ø. & Zachar, V., maj 2013, I : Stem Cell Research. 10, 3, s. 349–360 12 s.

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Cell Differentiation
Stem Cells
Epithelial Cells
Oxygen
Growth
16 Citationer (Scopus)

Transcriptional dissection of human limbal niche compartments by massive parallel sequencing

Søndergaard, C. B., Muttuvelu, D., Emmersen, J., Vorum, H., Hjortdal, J. Ø. & Zachar, V., 2013, I : P L o S One. 8, 5, e64244.

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Dissection
Stem cells
niches
Genes
stem cells
2012
20 Citationer (Scopus)

Activation of protease-activated receptor 2 induces VEGF independently of HIF-1

Rasmussen, J., Riis, S. E., Frøbert, O., Yang, S., Kastrup, J., Zachar, V., Simonsen, U. & Fink, T., 25 sep. 2012, I : P L o S One. 7, 9, s. Article No. e46087

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28 Citationer (Scopus)

Defined xenogeneic-free and hypoxic environment provides superior conditions for long-term expansion of human adipose-derived stem cells

Yang, S., Pilgaard, L., Chase, L. G., Boucher, S., Vemuri, M. C., Fink, T. & Zachar, V., 2012, I : Tissue Engineering. Part C. Methods. 18, 8, s. 593-602

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60 Citationer (Scopus)

Development and characterization of a clinically compliant xeno-free culture medium in good manufacturing practice for human multipotent mesenchymal stem cells

Chase, L. G., Yang, S., Zachar, V., Yang, Z., Lakshmipathy, U., Bradford, J., Boucher, S. E. & Vemuri, M. C., 2012, I : Stem Cells Translational Medicine. 1, 10, s. 750-758

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13 Citationer (Scopus)

Increased connective tissue attachment to silicone implants by a water vapor plasma treatment

Jensen, C., Gurevich, L., Patriciu, A., Struijk, J., Zachar, V. & Pennisi, C. P., 2012, I : Journal of Biomedical Materials Research. Part A. 100A, 12, s. 3400-3407

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23 Citationer (Scopus)

Patterned poly(lactic acid) films support growth and spontaneous multilineage gene expression of adipose-derived stem cells

Nielsen, S. F., Petersen, M., Fojan, P., Gurevich, L., Fink, T., Pennisi, C. P. & Zachar, V., 2012, I : Colloids and Surfaces B: Biointerfaces. 93, s. 92-99

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2011
40 Citationer (Scopus)

Adipogenic differentiation of human mesenchymal stem cells

Fink, T. & Zachar, V., 2011, I : Methods in Molecular Biology. 698, s. 243-251, kap. 19

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28 Citationer (Scopus)

Adipose-derived stem cells from the brown bear (Ursus arctos) spontaneously undergo chondrogenic and osteogenic differentiation in vitro

Fink, T., Rasmussen, J., Emmersen, J., Pilgaard, L., Fahlman, Å., Brunberg, S., Josefsson, J., Arnemo, J. M., Zachar, V., Swenson, J. E. & Fröbert, O., 2011, I : Stem Cell Research. 7, 1, s. 89-95

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34 Citationer (Scopus)

Hypoxia and adipose-derived stem cell-based tissue regeneration and engineering

Zachar, V., Duroux, M., Emmersen, J., Rasmussen, J. G., Pennisi, C. P., Yang, S. & Fink, T., 2011, I : Expert Opinion on Biological Therapy. 11, 6, s. 775-786

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26 Citationer (Scopus)

Isolation and expansion of adipose-derived stem cells for tissue engineering

Fink, T., Rasmussen, J. G., Lund, P., Pilgaard, L., Søballe, K. & Zachar, V., 2011, I : Frontiers in Bioscience. E3, 1, s. 256-263 8 s.

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Cell Engineering
Tissue Engineering
Stem cells
Tissue engineering
Stem Cells
30 Citationer (Scopus)

Isolation and growth of adipose tissue-derived stem cells

Zachar, V., Rasmussen, J. & Fink, T., 2011, I : Methods in Molecular Biology. 698, s. 37-49, kap. 4

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52 Citationer (Scopus)

Nanoscale topography reduces fibroblast growth, focal adhesion size and migration-related gene expression on platinum surfaces

Pennisi, C. P., Dolatshahi-Pirouz, A., Foss, M., Chevallier, J., Fink, T., Zachar, V., Besenbacher, F. & Yoshida, K., 2011, I : Colloids and Surfaces B: Biointerfaces. 85, 2, s. 189-197

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66 Citationer (Scopus)

Prolonged hypoxic culture and trypsinization increase the pro-angiogenic potential of human adipose tissue-derived stem cells

Rasmussen, J. G., Frøbert, O., Pilgaard, L., Kastrup, J., Simonsen, U., Zachar, V. & Fink, T., 2011, I : Cytotherapy. 13, 3, s. 318-328 11 s.

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30 Citationer (Scopus)

Uniaxial cyclic strain drives assembly and differentiation of skeletal myocytes

Pennisi, C. P., Olesen, C. G., de Zee, M., Rasmussen, J. & Zachar, V., 2011, I : Tissue Engineering. Part A. Tissue Engineering. 17, 19-20, s. 2543-2550

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2010
3 Citationer (Scopus)

Notch and Hedgehog signaling cooperate to maintain self-renewal of human embryonic stem cells exposed to low oxygen concentration

Weli, S. C., Fink, T., Cetinkaya, C., Prasad, M. S., Pennisi, C. P. & Zachar, V., 2010, I : International Journal of Stem Cells. 3, 2, s. 129-137 9 s.

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25 Citationer (Scopus)

The effect of human embryonic stem cells (hESCs) long-term normoxic and hypoxic cultures on the maintenance of pluripotency

Zachar, V., Prasad, M. S., Weli, S. C., Gabrielsen, A., Petersen, K., Petersen, M. B. & Fink, T., 2010, I : In Vitro Cellular & Developmental Biology - Animal. 46, 3-4, s. 276-283 8 s.

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2009
71 Citationer (Scopus)

Continuous hypoxic culturing maintains activation of Notch and allows long-term propagation of human embryonic stem cells without spontaneous differentiation

Prasad, M. S., Czepiel, M., Cetinkaya, C., Smigielska, K., Weli, S. C., Lysdahl, H., Gabrielsen, A., Petersen, K., Ehlers, N., Fink, T., Minger, S. L. & Zachar, V., 2009, I : Cell Proliferation. 42, 1, s. 63-74

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62 Citationer (Scopus)

Effect of growth media and serum replacements on the proliferation and differentiation of adipose-derived stem cells

Lund, P., Pilgaard, L., Crookshanks, M., Fink, T. & Zachar, V., 2009, I : Cytotherapy. 11, 2, s. 189-197

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33 Citationer (Scopus)

Effect of oxygen concentration, culture format and donor variability on in vitro chondrogenesis of human adipose tissue-derived stem cells

Pilgaard, L., Lund, P., Duroux, M., Fink, T., Ulrich-Vinter, M., Søballe, K. & Zachar, V., 2009, I : Regenerative Medicine. 4, 4, s. 539-548

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6 Citationer (Scopus)

Incorporation of photosynthetic reaction centers in the membrane of human cells: toward a new tool for optical control of cell activity

Pennisi, C. P., Jensen, P. E., Zachar, V., Greenbaum, E. & Yoshida, K., 2009, I : Cellular and Molecular Bioengeneering. 2, 1, s. 156-165

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8 Citationer (Scopus)

Minimal engraftment of human CD34+ cells mobilized from healthy donors in the infarcted heart of athymic nude rats

Sondergaard, C. S., Bonde, J., Dagnæs-Hansen, F., Nielsen, J. M., Zachar, V., Holm, M., Hokland, P. & Pedersen, L., 2009, I : Stem Cells and Development. 18, 6, s. 845-855

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28 Citationer (Scopus)

Responses of fibroblasts and glial cells to nanostructured platinum surfaces

Pennisi, C. P., Sevcencu, C., Dolatshahi-Pirouz, A., Foss, M., Hansen, J. L., Larsen, A. N., Zachar, V., Besenbacher, F. & Yoshida, K., 2009, I : Nanotechnology. 20, 38, s. Article ID 385103 9 s.

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41 Citationer (Scopus)

The influence of glancing angle deposited nano-rough platinum surfaces on the adsorption of fibrinogen and the proliferation of primary human fibroblasts

Dolatshahi-Pirouz, A., Pennisi, C. P., Skeldal, S., Foss, M., Chevallier, J., Zachar, V., Andreasen, P., Yoshida, K. & Besenbacher, F., 2009, I : Nanotechnology. 20, 9, 9 s.

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37 Citationer (Scopus)

Transcriptional signature of human adipose tissue-derived stem cells (hASCs) preconditioned for chondrogenesis in hypoxic conditions

Pilgaard, L., Lund, P., Duroux, M., Lockstone, H., Taylor, J., Emmersen, J., Fink, T., Ragoussis, J. & Zachar, V., 2009, I : Experimental Cell Research. 315, 11, s. 1937-1952

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2008
30 Citationer (Scopus)

Comparative analysis of highly defined proteases for the isolation of adipose tissue-derived stem cells

Pilgaard, L., Lund, P., Rasmussen, J. G., Fink, T. & Zachar, V., 2008, I : Regenerative Medicine. 3, 5, s. 705-715

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71 Citationer (Scopus)

Improved cellular activity of antisense peptide nucleic acids by conjugation to a cationic peptide-lipid (CatLip) domain

Koppelhus, U., Shiraishi, T., Zachar, V., Pankratova, S. & Nielsen, P. E., 2008, I : Bioconjugate Chemistry. 19, 8, s. 1526-1534

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94 Citationer (Scopus)

Instability of standard PCR reference genes in adipose-derived stem cells during propagation, differentiation and hypoxic exposure

Fink, T., Lund, P., Pilgaard, L., Rasmussen, J. G., Duroux, M. & Zachar, V., 2008, I : BMC Molecular Biology. 9, 9 s.

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