• Fredrik Bajers Vej 3, B, 1-216

    9220 Aalborg Ø

    Danmark

20072021
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Publikationer 2007 2019

2019
Hepcidins
Ficus
PC12 Cells
Iron
Messenger RNA
1 Citation (Scopus)
Hepcidins
PC12 Cells
Iron
Messenger RNA
Deferoxamine
1 Downloads (Pure)

Impairment of the Developing Human Brain in Iron Deficiency: Correlations to Findings in Experimental Animals and Prospects for Early Intervention Therapy

Markova, V., Holm, C., Pinborg, A. B., Thomsen, L. L. & Moos, T., 14 aug. 2019, I : Pharmaceuticals. 12, 3

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

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Secondary Prevention
Iron
Brain
Transferrin Receptors
Sus scrofa
8 Citationer (Scopus)

Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo

Johnsen, K. B., Bak, M., Melander, F., Thomsen, M. S., Burkhart, A., Kempen, P. J., Andresen, T. L. & Moos, T., 10 feb. 2019, I : Journal of Controlled Release. 295, s. 237-249 13 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Transferrin Receptors
Blood-Brain Barrier
Gold
Nanoparticles
Antibodies

Targeting the transferrin receptor for brain drug delivery

Bendix Johnsen, K., Burkhart, A., Bohn Thomsen, L., Andresen, T. L. & Moos, T., 1 okt. 2019, I : Progress in Neurobiology. 181, 101665.

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

Transferrin Receptors
Blood-Brain Barrier
Brain
Pharmaceutical Preparations
Nanomedicine
2018
12 Citationer (Scopus)
538 Downloads (Pure)

Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles

Johnsen, K. B., Bak, M., Kempen, P. J., Melander, F., Burkhart, A., Thomsen, M. S., Nielsen, M. S., Moos, T. & Andresen, T. L., 2018, I : Theranostics. 8, 12, s. 3416-3436

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Transferrin Receptors
Antibody Affinity
Gold
Nanoparticles
Nanomedicine
3 Citationer (Scopus)
73 Downloads (Pure)

Iron deficiency and iron treatment in the fetal developing brain: a pilot study introducing an experimental rat model

Moos, T., Skjørringe, T. & Thomsen, L. L., 22 jun. 2018, I : Reproductive Health. 15, Suppl. 1, s. 117-120 93.

Publikation: Bidrag til tidsskriftKonferenceartikel i tidsskriftForskningpeer review

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Theoretical Models
Iron
Brain
Therapeutics
Mothers
12 Citationer (Scopus)

On the use of liposome controls in studies investigating the clinical potential of extracellular vesicle-based drug delivery systems: A commentary

Johnsen, K. B., Gudbergsson, J. M., Duroux, M., Moos, T., Andresen, T. L. & Simonsen, J. B., 2018, I : Journal of Controlled Release. 269, s. 10-14

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

Drug Delivery Systems
Liposomes
Nanoparticles
Pharmaceutical Preparations
Therapeutic Uses
4 Citationer (Scopus)

The endo-lysosomal system of brain endothelial cells is influenced by astrocytes in vitro

Toth, A. E., Siupka, P., P Augustine, T. J., Venø, S. T., Thomsen, L. B., Moos, T., Lohi, H. T., Madsen, P., Lykke-Hartmann, K. & Nielsen, M. S., nov. 2018, I : Molecular Neurobiology. 55, 11, s. 8522-8537 16 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Astrocytes
Endothelial Cells
Brain
Blood-Brain Barrier
Transcytosis
2017
10 Citationer (Scopus)

Bidirectional apical-basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells

Siupka, P., Hersom, M. N. S., Lykke-Hartmann, K., Johnsen, K. B., Thomsen, L. B., Andresen, T. L., Moos, T., Abbott, N. J., Brodin, B. & Nielsen, M. S., 2017, I : Journal of Cerebral Blood Flow and Metabolism. 37, 7, s. 2598–2613

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

IGF Type 2 Receptor
Cations
Endothelial Cells
Brain
Transferrin Receptors
13 Citationer (Scopus)
Endothelial cells
Pericytes
Blood-Brain Barrier
Basement Membrane
Brain
36 Citationer (Scopus)
44 Downloads (Pure)

Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

Johnsen, K. B., Burkhart, A., Melander, F., Kempen, P. J., Vejlebo, J. B., Siupka, P., Nielsen, M. S., Andresen, T. L. & Moos, T., 1 dec. 2017, I : Scientific Reports. 7, 13 s., 10396.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Transferrin Receptors
Blood-Brain Barrier
Brain
Endothelium
Transcytosis
12 Citationer (Scopus)
153 Downloads (Pure)

The choroid plexus as a site of damage in hemorrhagic and ischemic stroke and its role in responding to injury

Xiang, J., Routhe, L. J., Andrew Wilkinson, D., Hua, Y., Moos, T., Xi, G. & Keep, R. F., 28 mar. 2017, I : Fluids and Barriers of the CNS. 14, 13 s., 8.

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

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Fil
Choroid Plexus
Stroke
Wounds and Injuries
Hemorrhage
Cerebral Hemorrhage
31 Citationer (Scopus)

The vascular basement membrane in the healthy and pathological brain

Thomsen, M. S., Routhe, L. J. & Moos, T., okt. 2017, I : Journal of Cerebral Blood Flow and Metabolism. 37, 10, s. 3300-3317

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

Basement Membrane
Blood Vessels
Brain
Pericytes
Endothelial Cells
2 Citationer (Scopus)
Erythropoietin
Transfection
Endothelial Cells
Brain
Proteins
2016

A triple co-culture model of the blood-brain barrier using primary porcine brain endothelial cells, porcine pericytes and porcine astrocytes

Thomsen, L. B., Larsen, A. B. & Moos, T., 2016, IPC nr. C12N 5/071 (2010.01), C12N 5/079 (2010.01), G01N 33/50 (2006.01), Patentnr. WO/2016/202343 , 22 dec. 2016, Prioritetsdato 16 jun. 2016, Prioritetsnr. PCT/DK2016/050190

Publikation: PatentForskning

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Behandlingen af Alzheimers sygdom: det er vanskeligt at forstå, hvordan passiv immunterapi virker

Moos, T. & Thomsen, M. S., 2016, I : Ugeskrift for Laeger. 178, 15, s. 1457

Publikation: Bidrag til tidsskriftKommentar/debatForskning

19 Citationer (Scopus)

Evaluation of electroporation-induced adverse effects on adipose-derived stem cell exosomes

Johnsen, K. B., Gudbergsson, J. M., Skov, M. N., Christiansen, G., Gurevich, L., Moos, T. & Duroux, M., 2016, I : Cytotechnology. 68, 5, s. 2125–2138

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Exosomes
Electroporation
Stem Cells
Glioblastoma
Pharmaceutical Preparations

Expression and deposition of basement membrane proteins by brain capillary endothelial cells in a primary murine model of the blood-brain barrier

Thomsen, M. S., Birkelund, S., Larsen, A. B., Stensballe, A. & Moos, T., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 37 P-12

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

25 Citationer (Scopus)

Expression of iron-related proteins at the neurovascular unit supports reduction and reoxidation of iron for transport through the blood-brain barrier

Burkhart, A., Skjørringe, T., Johnsen, K. B., Siupka, P., Thomsen, L. B., Nielsen, M. S., Thomsen, L. L. & Moos, T., 2016, I : Molecular Neurobiology. 53, 10, s. 7237-7253

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Blood-Brain Barrier
Iron
Ceruloplasmin
Brain
Endothelial Cells

Gene delivery of the therapeutic polypeptide erythropoietin to primary brain capillary endothelial cells for protein secretion

Larsen, A. B. & Moos, T., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 25 O-5

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

5 Citationer (Scopus)
133 Downloads (Pure)

Geographical variation in antipsychotic drug use in elderly patients with dementia: a nationwide study

Zakarias, J. K., Jensen-Dahm, C., Nørgaard, A., Stevnsborg, L., Gasse, C., Andersen, B. G., Søren, J., Waldorff, F. B., Moos, T. & Waldemar, G., 2016, I : Journal of Alzheimer's Disease. 54, 3, s. 1183-1192

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Fil
Antipsychotic Agents
Dementia
Denmark
Behavioral Symptoms
Caregivers
120 Downloads (Pure)

Metal-dependent regulation of ATP7A and ATP7B in fibroblast cultures

Lenartowicz, M., Moos, T., Ogórek, M., Jensen, T. G. & Møller, L. B., 2016, I : Frontiers in Molecular Neuroscience. 9, 68.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Copper
Fibroblasts
Metals
Menkes Kinky Hair Syndrome
Hepatolenticular Degeneration

Proteomics-driven design of endothelial stress-based protein array for disease prognostics: applied to plasma and cerebrospinal fluid

Kastaniegaard, K., Jørgensen, M. M., Bæk, R., Sejrbæk, T., Wiwie, C., Baumbach, J., Zachar, V., Moos, T., Nielsen, S., Nieland, J. D., Cotton, F., Guttmann, C., Illes, Z. & Stensballe, A., 2016, I : Journal of Extracellular Vesicles. 5, Suppl. 1, s. 4 1 s., OW2.2.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

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39 Citationer (Scopus)

Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier

Moos, T., Routhe, L. J., Birkelund, S., Burkhart, A., Stensballe, A. & Thomsen, M. S., 2016, 46th Annual Meeting of the Society for Neuroscience, Neuroscience 2016, 12-16 November 2016, San Diego, CA, USA. Society for Neuroscience, 140.10 / U1

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

Åben adgang
6 Citationer (Scopus)

Targeted vascular drug delivery in cerebral cancer

Humle, N., Johnsen, K. B., Arendt, G. A., Nielsen, R. P., Moos, T. & Thomsen, L. B., 2016, I : Current Pharmaceutical Design. 22, 35, s. 5487-5504

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

Glioblastoma
Blood Vessels
Pharmaceutical Preparations
Neoplasms
Brain Neoplasms

Targeting immunoliposomes to transferrin receptors on brain capillary endothelial cells as a mean for cargo transport across the blood-brain barrier

Johnsen, K. B., Larsen, A. B., Bruun, J., Siupka, P., Nielsen, M. S., Andresen, T. L. & Moos, T., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 51 P-51

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

Targeting immunoliposomes to transferrin receptors on brain capillary endothelial cells as a mean for cargo transport across the blood-brain barrier

Moos, T., Johnsen, K. B., Burkhart, A., Bruun, J., Siupka, P., Nielsen, M. S. & Andresen, T., 2016, 46th Annual Meeting of the Society for Neuroscience, Neuroscience 2016, 12-16 November 2016, San Diego, CA, USA. Society for Neuroscience, 140.13 / U4

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

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Trafficking of Transferrin Receptor in primary porcine brain endothelial cells and its implication for drug delivery to the brain

Siupka, P., Thomsen, L. B., Lykke-Hartmann, K., Moos, T. & Nielsen, M. S., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 27 O-9

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

Vesicular transport in brain microvascular endothelial cells

Toth, A., Siupka, P., Pulikotial, A. T., Thomsen, L. B., Lohi, H. T., Lykke-Hartmann, K., Moos, T., Madsen, P. & Nielsen, M. S., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 42-43 P-29

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

2015

A novel transgenic mouse line co-expressing alpha-synuclein and p25alpha displays increased oligomer formation

Lassen, L. B., Jensen, P. H., Betzer, C. & Moos, T., 2015, 45th Annual Meeting of the Society for Neuroscience, Neuroscience 2015, 17-21 October 2015, Chicago, IL, USA. Society for Neuroscience, s. No. 647.10

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

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50 Citationer (Scopus)
210 Downloads (Pure)

A triple culture model of the blood-brain barrier using porcine brain endothelial cells, astrocytes and pericytes

Thomsen, L. B., Burkhart, A. & Moos, T., 2015, I : PLOS ONE. 10, 8, 16 s., e0134765.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Pericytes
blood-brain barrier
astrocytes
Endothelial cells
Blood-Brain Barrier
50 Citationer (Scopus)
209 Downloads (Pure)
Åben adgang
Fil
3 Citationer (Scopus)

Handling iron in restorative neuroscience

Routhe, L. J. & Moos, T., 2015, I : Neural Regeneration Research. 10, 10, s. 1558-1559

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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24 Citationer (Scopus)

Neurodegeneration with inflammation is accompanied by accumulation of iron and ferritin in microglia and neurons

Thomsen, M. S., Andersen, M. V., Christoffersen, P. R., Jensen, M. D., Lichota, J. & Moos, T., 2015, I : Neurobiology of Disease. 81, s. 108-118

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Repercussions of glioblastoma multiforme on the blood-brain barrier

Humle, N. H., Thomsen, L. B. & Moos, T., 2015, I : Clinical Neuropathology. 34, 3, s. 149

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Åben adgang
24 Citationer (Scopus)

Targeted drug delivery to the brain using magnetic nanoparticles

Thomsen, L. B., Thomsen, M. S. & Moos, T., 2015, I : Therapeutic Delivery. 6, 10, s. 1145-1155

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Nanoparticles
Blood-Brain Barrier
Endothelial Cells
Brain
Pharmaceutical Preparations

The invasive nature of primary GBM cell lines: importance of paracrine signaling

Pilgaard, L., Elbæk, K. J., Gudbergsson, J. M., Stensballe, A., Moos, T., Zachar, V., Agger, R. & Doroux, M., 2015, I : Clinical Neuropathology. 34, 3, s. 159

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

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20 Citationer (Scopus)
239 Downloads (Pure)

Transfection of brain capillary endothelial cells in primary culture with defined blood-brain barrier properties

Larsen, A. B., Thomsen, L. B., Thomsen, M. S., Lichota, J., Fazakas, C., Krizbai, I. & Moos, T., 2015, I : Fluids and Barriers of the CNS. 12, 1, 14 s., 19.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Blood-Brain Barrier
Transfection
Endothelial Cells
Brain
Astrocytes
2014
8 Citationer (Scopus)

Accessing targeted nanoparticles to the brain: the vascular route

Burkhart, A., Azizi, M., Thomsen, M. S., Thomsen, L. B. & Moos, T., 2014, I : Current Medicinal Chemistry. 21, 36, s. 4092-4099

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

267 Citationer (Scopus)

A comprehensive overview of exosomes as drug delivery vehicles: endogenous nanocarriers for targeted cancer therapy

Johnsen, K. B., Gudbergsson, J. M., Skov, M. N., Pilgaard, L., Moos, T. & Duroux, M., 2014, I : B B A - Reviews on Cancer. 1846, 1, s. 75–87

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

Ceruloplasmin is expressed by brain pericytes

Moos, T. & Larsen, A. B., 2014, Annual Meeting of the Society for Neuroscience, Neuroscience 2014, 15-19 November 2014, Washington, DC, USA. s. Poster No. 739.01/QQ4

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskning

16 Citationer (Scopus)

Cripto-1 expression in glioblastoma multiforme

Pilgaard, L., Mortensen, J. H., Henriksen, M., Olesen, P., Sørensen, P., Laursen, R. J., Vyberg, M., Agger, R., Zachar, V., Moos, T. & Duroux, M., 2014, I : Brain Pathology. 24, 4, s. 360–370

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

16 Citationer (Scopus)

Cripto-1 expression in glioblastoma multiforme

Duroux, M., Olesen, P., Pilgaard, L., Henriksen, M., Mortensen, J. H., Sørensen, P., Laursen, R. J., Vyberg, M., Agger, R., Zachar, V. & Moos, T., 2014, Proceedings of the 5th Disputationes : Addressing Organ Regeneration and Tissue Repair by Artificial Supports, 12-13 May 2014, Aalborg, Denmark.

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskning

Gene delivery of therapeutic polypeptides to brain capillary endothelial cells for protein secretion

Larsen, A. B., Thomsen, L. B. & Moos, T., 2014.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

59 Citationer (Scopus)

Iron deposits in the chronically inflamed central nervous system and contributes to neurodegeneration

Andersen, H. H., Johnsen, K. B. & Moos, T., 2014, I : Cellular and Molecular Life Sciences. 71, 9, s. 1607-1622

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)Forskningpeer review

Åben adgang

Iron uptake and transport at the blood-brain barrier

Larsen, A. B., Thomsen, L. B. & Moos, T., 2014.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

2013

A decrease in neuronal ferroportin accompanies chronic brain inflammation with iron deposition

Andersen, M. V., Christoffersen, P. R., Jensen, M. D., Lichota, J. & Moos, T., 2013, I : American Journal of Hematology. 88, 5, E162, No. 206.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review