• Fredrik Bajers Vej 3, B, 1-216

    9220 Aalborg Ø

    Danmark

20072021
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Publikationer 2007 2019

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Tidsskriftartikel
2019
1 Citation (Scopus)
Hepcidins
PC12 Cells
Iron
Messenger RNA
Deferoxamine
11 Citationer (Scopus)

Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo

Johnsen, K. B., Bak, M., Melander, F., Thomsen, M. S., Burkhart, A., Kempen, P. J., Andresen, T. L. & Moos, T., 10 feb. 2019, I : Journal of Controlled Release. 295, s. 237-249 13 s.

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Transferrin Receptors
Blood-Brain Barrier
Gold
Nanoparticles
Antibodies
2018
13 Citationer (Scopus)
559 Downloads (Pure)

Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles

Johnsen, K. B., Bak, M., Kempen, P. J., Melander, F., Burkhart, A., Thomsen, M. S., Nielsen, M. S., Moos, T. & Andresen, T. L., 2018, I : Theranostics. 8, 12, s. 3416-3436

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Transferrin Receptors
Antibody Affinity
Gold
Nanoparticles
Nanomedicine
4 Citationer (Scopus)

The endo-lysosomal system of brain endothelial cells is influenced by astrocytes in vitro

Toth, A. E., Siupka, P., P Augustine, T. J., Venø, S. T., Thomsen, L. B., Moos, T., Lohi, H. T., Madsen, P., Lykke-Hartmann, K. & Nielsen, M. S., nov. 2018, I : Molecular Neurobiology. 55, 11, s. 8522-8537 16 s.

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Astrocytes
Endothelial Cells
Brain
Blood-Brain Barrier
Transcytosis
2017
10 Citationer (Scopus)

Bidirectional apical-basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells

Siupka, P., Hersom, M. N. S., Lykke-Hartmann, K., Johnsen, K. B., Thomsen, L. B., Andresen, T. L., Moos, T., Abbott, N. J., Brodin, B. & Nielsen, M. S., 2017, I : Journal of Cerebral Blood Flow and Metabolism. 37, 7, s. 2598–2613

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IGF Type 2 Receptor
Cations
Endothelial Cells
Brain
Transferrin Receptors
16 Citationer (Scopus)
Endothelial cells
Pericytes
Blood-Brain Barrier
Basement Membrane
Brain
40 Citationer (Scopus)
61 Downloads (Pure)

Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

Johnsen, K. B., Burkhart, A., Melander, F., Kempen, P. J., Vejlebo, J. B., Siupka, P., Nielsen, M. S., Andresen, T. L. & Moos, T., 1 dec. 2017, I : Scientific Reports. 7, 13 s., 10396.

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Transferrin Receptors
Blood-Brain Barrier
Brain
Endothelium
Transcytosis
2 Citationer (Scopus)
Erythropoietin
Transfection
Endothelial Cells
Brain
Proteins
2016
20 Citationer (Scopus)

Evaluation of electroporation-induced adverse effects on adipose-derived stem cell exosomes

Johnsen, K. B., Gudbergsson, J. M., Skov, M. N., Christiansen, G., Gurevich, L., Moos, T. & Duroux, M., 2016, I : Cytotechnology. 68, 5, s. 2125–2138

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Åben adgang
Exosomes
Electroporation
Stem Cells
Glioblastoma
Pharmaceutical Preparations
28 Citationer (Scopus)

Expression of iron-related proteins at the neurovascular unit supports reduction and reoxidation of iron for transport through the blood-brain barrier

Burkhart, A., Skjørringe, T., Johnsen, K. B., Siupka, P., Thomsen, L. B., Nielsen, M. S., Thomsen, L. L. & Moos, T., 2016, I : Molecular Neurobiology. 53, 10, s. 7237-7253

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Blood-Brain Barrier
Iron
Ceruloplasmin
Brain
Endothelial Cells
6 Citationer (Scopus)
156 Downloads (Pure)

Geographical variation in antipsychotic drug use in elderly patients with dementia: a nationwide study

Zakarias, J. K., Jensen-Dahm, C., Nørgaard, A., Stevnsborg, L., Gasse, C., Andersen, B. G., Søren, J., Waldorff, F. B., Moos, T. & Waldemar, G., 2016, I : Journal of Alzheimer's Disease. 54, 3, s. 1183-1192

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Åben adgang
Fil
Antipsychotic Agents
Dementia
Denmark
Behavioral Symptoms
Caregivers
136 Downloads (Pure)

Metal-dependent regulation of ATP7A and ATP7B in fibroblast cultures

Lenartowicz, M., Moos, T., Ogórek, M., Jensen, T. G. & Møller, L. B., 2016, I : Frontiers in Molecular Neuroscience. 9, 68.

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Åben adgang
Fil
Copper
Fibroblasts
Metals
Menkes Kinky Hair Syndrome
Hepatolenticular Degeneration
2015
54 Citationer (Scopus)
233 Downloads (Pure)

A triple culture model of the blood-brain barrier using porcine brain endothelial cells, astrocytes and pericytes

Thomsen, L. B., Burkhart, A. & Moos, T., 2015, I : PLOS ONE. 10, 8, 16 s., e0134765.

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Åben adgang
Fil
Pericytes
blood-brain barrier
astrocytes
Endothelial cells
Blood-Brain Barrier
56 Citationer (Scopus)
228 Downloads (Pure)
Åben adgang
Fil
3 Citationer (Scopus)

Handling iron in restorative neuroscience

Routhe, L. J. & Moos, T., 2015, I : Neural Regeneration Research. 10, 10, s. 1558-1559

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Åben adgang
26 Citationer (Scopus)

Neurodegeneration with inflammation is accompanied by accumulation of iron and ferritin in microglia and neurons

Thomsen, M. S., Andersen, M. V., Christoffersen, P. R., Jensen, M. D., Lichota, J. & Moos, T., 2015, I : Neurobiology of Disease. 81, s. 108-118

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25 Citationer (Scopus)

Targeted drug delivery to the brain using magnetic nanoparticles

Thomsen, L. B., Thomsen, M. S. & Moos, T., 2015, I : Therapeutic Delivery. 6, 10, s. 1145-1155

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Nanoparticles
Blood-Brain Barrier
Endothelial Cells
Brain
Pharmaceutical Preparations
21 Citationer (Scopus)
256 Downloads (Pure)

Transfection of brain capillary endothelial cells in primary culture with defined blood-brain barrier properties

Larsen, A. B., Thomsen, L. B., Thomsen, M. S., Lichota, J., Fazakas, C., Krizbai, I. & Moos, T., 2015, I : Fluids and Barriers of the CNS. 12, 1, 14 s., 19.

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Åben adgang
Fil
Blood-Brain Barrier
Transfection
Endothelial Cells
Brain
Astrocytes
2014
8 Citationer (Scopus)

Accessing targeted nanoparticles to the brain: the vascular route

Burkhart, A., Azizi, M., Thomsen, M. S., Thomsen, L. B. & Moos, T., 2014, I : Current Medicinal Chemistry. 21, 36, s. 4092-4099

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16 Citationer (Scopus)

Cripto-1 expression in glioblastoma multiforme

Pilgaard, L., Mortensen, J. H., Henriksen, M., Olesen, P., Sørensen, P., Laursen, R. J., Vyberg, M., Agger, R., Zachar, V., Moos, T. & Duroux, M., 2014, I : Brain Pathology. 24, 4, s. 360–370

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2013
9 Citationer (Scopus)

Development of a Novel Lipophilic, Magnetic Nanoparticle for in Vivo Drug Delivery

Linemann, T., Thomsen, L. B., du Jardin, K. G., Laursen, J. C., Jensen, J. B., Lichota, J. & Moos, T., 2013, I : Pharmaceutics. 5, 2, s. 246-260

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Targeted antiepidermal growth factor receptor (Cetuximab) immunoliposomes enhance cellular uptake in vitro and exhibit increased accumulation in an intracranial model of glioblastoma multiforme

Mortensen, J. H., Jeppesen, M., Pilgaard, L., Agger, R., Duroux, M., Zachar, V. & Moos, T., 2013, I : Journal of Drug Delivery. 2013, s. Article No. 209205 13 s.

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42 Citationer (Scopus)

Uptake and transport of superparamagnetic iron oxide nanoparticles through human brain capillary endothelial cells

Thomsen, L. B., Linemann, T., Pondman, K. M., Lichota, J., Kim, K. S., Pieters, R. J., Visser, G. M. & Moos, T., 2013, I : ACS Chemical Neuroscience. 4, 10, s. 1352-1360

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2012
12 Citationer (Scopus)

Brain delivery systems via mechanism independent of receptor-mediated endocytosis and adsorptive-mediated endocytosis

Thomsen, L. B., Lichota, J., Eskehave, T. N., Linemann, T., Mortensen, J. H., du Jardin, K. G. & Moos, T., 2012, I : Current Pharmaceutical Biotechnology. 13, 12, s. 2349-2354

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14 Citationer (Scopus)

Chronic vitamin C deficiency does not accelerate oxidative stress in ageing brains of guinea pigs

Tveden-Nyborg, P., Hasselholt, S., Miyashita, N., Moos, T., Poulsen, H. E. & Lykkesfeldt, J., 2012, I : Basic & Clinical Pharmacology & Toxicology. 110, 6, s. 524-529

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37 Citationer (Scopus)

Impairment of interrelated iron- and copper homeostatic mechanisms in brain contributes to the pathogenesis of neurodegenerative disorders

Skjørringe, T., Møller, L. B. & Moos, T., 2012, I : Frontiers in Pharmacology. 3, s. Article No. 169 14 s.

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2011
9 Citationer (Scopus)

Developmental iron uptake and axonal transport in the retina of the rat

Moos, T., Bernth, N., Courtois, Y. & Morgan, E. H., 2011, I : Molecular and Cellular Neuroscience. 46, 3, s. 607-613

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41 Citationer (Scopus)

Gene delivery by pullulan derivatives in brain capillary endothelial cells for protein secretion

Thomsen, L. B., Lichota, J., Kim, K. S. & Moos, T., 2011, I : Journal of Controlled Release. 151, 1, s. 45-50

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27 Citationer (Scopus)

Heterogenous distribution of ferroportin-containing neurons in mouse brain

Boserup, M. W., Lichota, J., Haile, D. & Moos, T., 2011, I : BioMetals. 24, 2, s. 357-375

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2010

Enabling drug delivery to cancer cells and tumor endothelium: the benefit of targeted therapy

Jeppesen, M. & Moos, T., 2010, I : Frontiers in Drug Design and Discovery. 5, s. 146-167

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51 Citationer (Scopus)

Macromolecular drug transport into the brain using targeted therapy

Lichota, J., Skjørringe, T., Thomsen, L. B. & Moos, T., 2010, I : Journal of Neurochemistry. 113, 1, s. 1-13 13 s.

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2009
34 Citationer (Scopus)

Fulminant lymphocytic choriomeningitis virus-induced inflammation of the CNS involves a cytokine-chemokine-cytokine-chemokine cascade

Christensen, J. E., Simonsen, S., Fenger, C., Sorensen, M. R., Moos, T., Christensen, J. P., Finsen, B. & Thomsen, A. R., 2009, I : Journal of Immunology. 182, 2, s. 1079-1087

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2008
34 Citationer (Scopus)

Ubxd1 is a novel co-factor of the human p97 ATPase

Madsen, L., Andersen, K. M., Prag, S., Moos, T., Semple, C. A., Seeger, M. & Hartmann-Petersen, R., 2008, I : International Journal of Biochemistry & Cell Biology. 40, 12, s. 2927-2942

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2007
241 Citationer (Scopus)

Iron trafficking inside the brain

Moos, T., Nielsen, T. R., Skjørringe, T. & Morgan, E. H., 2007, I : Journal of Neurochemistry. 103, 5, s. 1730-1740

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