Projekter pr. år
Personlig profil
Forskningsprofil
Our innate immune system is the first to interact with pathogens (e.g. bacteria and virus) and is central in protecting us from infections and determining the final outcome. This is especially true for the very young where the immune system (innate and adaptive) is immature, rendering them increasingly susceptible to infectious diseases. At the same time, unfavorable immune reactions can lead to autoimmune diseases with a significant negative impact. My research focus is to understand the development of the human immune system in early life, with a particular focus on the innate immune system, and as an extension of this understand how immune reactions lead to autoimmune diseases. The main methods I apply are OMICS (Big Data) with bioinformatics including machine learning strategies. The perspective is to facilitate better treatment strategies and diagnostic tools.
Full list of publications: http://scholar.google.com/citations?user=v_zRbfcAAAAJ
CV: https://www.linkedin.com/in/tubenn
Undervisningsprofil
I teach on all academic levels at the university, from 1st semester to PhD level. PBL is a central element in all my teaching activities, and I have attended a number of PBL- andcase-based workshops.
Main subjects:
- Biochemistry
- Eucaryotic cell biology
- Enzyme kinetics
- Bioinformatics
- Proteomics analysis
- Course for case cafilitators
Main methods:
- Lectures with 10-300 students, physical and online with ongoing assignments.
- Project supervision. individual and in groups with laboratory and bioinformatics elements.
- Facilitation of problem-based case learning.
Administrativ profil
- Profile track coordinator Translational Medicine MedIS Master Education.
- Studyboard for medicine.
- Semester coordinator 2nd semester MedIS Master.
- Module Coordinator 1.1, Medicine and MedIS Bachelor level.
- Chair for Digital PBL @ SUND Casework.
- Coordinator for Implementation of Digital Competences in the Medicine and MedIS Study Curriculum.
Ph.d.-vejledning
- PhD Co-supervisor for Karen Mai Møllegaard (2021 - )
- PhD Co-supervisor for Laura Lind Throne Degn (2021 - )
- PhD assessment committe chairman Rocco Giordano (2021)
- PhD assessment committe chairman Jonas Ellegaard Nielsen (2021)
Ekspertise relateret til FN’s Verdensmål
I 2015 blev FN's medlemslande enige om 17 Verdensmål til at bekæmpe fattigdom, beskytte planeten og sikre velstand for alle. Denne persons arbejde bidrager til følgende verdensmål:
Uddannelse (Akademiske kvalifikationer)
Postdoctoral researcher, The innate immune system and inflammation: Proteomics and bioinformatics, Harvard University
1 okt. 2015 → 31 mar. 2017
Postdoctoral resaercher, The innate immune system in inflammatory bowel diseases, Regional Hospital Southern Denmark
1 apr. 2014 → 31 mar. 2015
Eksterne ansættelser
Adjunct Associate Professor in Inflammatory Diseases, University of Southern Denmark
1 apr. 2021 → 31 mar. 2026
Emneord
- Biomedicin
- Medicin
- Kemi og Biovidenskab
Fingerprint
- 1 Lignende profiler
Samarbejde i de sidste fem år
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EPIC-HIPC: Systems Biology to Identify Biomarkers of Neonatal Vaccine Immunogenicity (EPIC-HIPC)
01/01/2016 → 01/01/2022
Projekter: Projekt › Forskning
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TPIAT: Molecular markers of pancreatitis patients, pre- and post Total Pancreatectomy with Islet AutoTransplantation surgery
01/01/2016 → …
Projekter: Projekt › Forskning
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The innate immune system: Ontogeny and role in inflammatory diseases
Lundbeckfonden, A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal, Carlsbergfondet
01/01/2014 → …
Projekter: Projekt › Forskning
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BreathOMICS
Gade, I. L., Bennike, T. B., Kristensen, S. R. & Honoré, B.
Projekter: Projekt › Forskning
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MassIVE: Re-analysis of publicly available proteomics datasets
20/10/2016 → 01/03/2019
Projekter: Projekt › Forskning
Publikationer
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Dynamic molecular changes during the first week of human life follow a robust developmental trajectory
Lee, A. H., Shannon, C. P., Amenyogbe, N., Bennike, T. B., Diray-Arce, J., Idoko, O. T., Gill, E. E., Ben-Othman, R., Pomat, W. S., van Haren, S. D., Cao, K. A. L., Cox, M., Darboe, A., Falsafi, R., Ferrari, D., Harbeson, D. J., He, D., Bing, C., Hinshaw, S. J., Ndure, J., & 24 flere , 12 mar. 2019, I: Nature Communications. 10, 1, 14 s., 1092.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil108 Citationer (Scopus)77 Downloads (Pure) -
A clinical proteomics study of exhaled breath condensate and biomarkers for pulmonary embolism
Gade, I. L., Juul Riddersholm, S., Stilling-Vinther, T., Brøndum, R. F., Bennike, T. B. & Honoré, B., 17 nov. 2023, I: Journal of Breath Research. 18, 1, 016007.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil2 Downloads (Pure) -
Advances in proteomics: characterization of the innate immune system after birth and during inflammation
Bennike, T. B., 6 okt. 2023, I: Frontiers in Immunology. 14, 1254948.Publikation: Bidrag til tidsskrift › Review (oversigtsartikel) › peer review
Åben adgangFil4 Downloads (Pure) -
Complement killing of clinical Klebsiella pneumoniae isolates is serum concentration dependent
Opstrup, K. V., Bennike, T. B., Christiansen, G. & Birkelund, S., maj 2023, I: Microbes and Infection. 25, 4, 105074.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
2 Citationer (Scopus) -
Impaired Abcb1a function and red meat in a translational colitis mouse model induces inflammation and alters microbiota composition
Stensballe, A., Bennike, T. B., Ravn-Haren, G., Mortensen, A., Aboo, C., Knudsen, L. A., Rühlemann, M. C., Birkelund, S., Bang, C., Franke, A., Vogel, U., Hansen, A. K. & Andersen, V., 31 jul. 2023, I: Frontiers in Medicine. 10, 1200317.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil6 Downloads (Pure)
Forskningsdatasæt
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Additional file 1 of Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
Birkelund, S. (Ophavsperson), Bennike, T. B. (Ophavsperson), Kastaniegaard, K. (Ophavsperson), Lausen, M. (Ophavsperson), Poulsen, T. B. G. (Ophavsperson), Kragstrup, T. W. (Ophavsperson), Deleuran, B. W. (Ophavsperson), Christiansen, G. (Ophavsperson) & Stensballe, A. (Ophavsperson), Figshare, 6 aug. 2020
DOI: 10.6084/m9.figshare.12775188.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Proteomic_analysis_of_synovial_fluid_from_rheumatic_arthritis_and_spondyloarthritis_patients/12775188/1 og et link mere, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Proteomic_analysis_of_synovial_fluid_from_rheumatic_arthritis_and_spondyloarthritis_patients/12775188 (vis færre)
Datasæt
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Complement deposition on Chlamydia trachomatis
Bennike, T. B. (Ophavsperson), Nielsen, M. L. (Ophavsperson), Thomsen, M. E. (Ophavsperson), Christiansen, G. (Ophavsperson), Karred, N. (Ophavsperson), Stensballe, A. (Ophavsperson) & Birkelund, S. (Ophavsperson), PRoteomics IDEntifications Database (PRIDE), 26 maj 2020
https://www.ebi.ac.uk/pride/archive/projects/PXD019393
Datasæt
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Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
Birkelund, S. (Ophavsperson), Bennike, T. B. (Ophavsperson), Kastaniegaard, K. (Ophavsperson), Lausen, M. (Ophavsperson), Poulsen, T. B. G. (Ophavsperson), Kragstrup, T. W. (Ophavsperson), Deleuran, B. W. (Ophavsperson), Christiansen, G. (Ophavsperson) & Stensballe, A. (Ophavsperson), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5085102.v1, https://doi.org/10.6084%2Fm9.figshare.c.5085102.v1
Datasæt
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Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
Birkelund, S. (Ophavsperson), Bennike, T. B. (Ophavsperson), Kastaniegaard, K. (Ophavsperson), Lausen, M. (Ophavsperson), Poulsen, T. B. G. (Ophavsperson), Kragstrup, T. W. (Ophavsperson), Deleuran, B. W. (Ophavsperson), Christiansen, G. (Ophavsperson) & Stensballe, A. (Ophavsperson), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5085102, https://springernature.figshare.com/collections/Proteomic_analysis_of_synovial_fluid_from_rheumatic_arthritis_and_spondyloarthritis_patients/5085102
Datasæt
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Depleted Prefractionated Human Plasma for Data Independent Acquisition Spectral Library
Bennike, T. B. (Ophavsperson), Bellin, M. D. (Bidrager), Xuan, Y. (Bidrager), Stensballe, A. (Bidrager), Møller, F. T. (Bidrager), Beilman, G. (Bidrager), Levy, O. (Bidrager), Cruz-Monserrate, Z. (Bidrager), Andersen, V. (Bidrager), Steen, J. (Bidrager), Conwell, D. L. (Bidrager) & Steen, H. (Bidrager), PRoteomics IDEntifications Database (PRIDE), 18 apr. 2018
https://www.ebi.ac.uk/pride/archive/projects/PXD008163
Datasæt
Aktiviteter
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Ontogeny of the plasma proteome across the first week of human life
Tue Bjerg Bennike (Foredragsholder)
18 okt. 2019Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
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Frontiers in Immunology (Tidsskrift)
Tue Bjerg Bennike (Fagfællebedømmer)
3 aug. 2022Aktivitet: Redaktionelt arbejde og fagfællebedømmelse › Peer reviewer/fagfællebedømmer af manuskripter › Forskning
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Frontiers in Immunology (Tidsskrift)
Tue Bjerg Bennike (Fagfællebedømmer)
30 jun. 2022Aktivitet: Redaktionelt arbejde og fagfællebedømmelse › Peer reviewer/fagfællebedømmer af manuskripter › Forskning
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Bottom-up proteomic analysis of the exhaled breath condensate from twenty-six individual healthy persons
Inger Lise Gade (Foredragsholder), Tue Bjerg Bennike (Foredragsholder), Søren Risom Kristensen (Andet) & Bent Honoré (Andet)
14 jun. 2022Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
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Autoimmune diseases and breach of immune tolerance
Tue Bjerg Bennike (Foredragsholder)
3 feb. 2022Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
Presse/medier
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Bedre børnevaccination med Big Data: Ny forskning kortlægger nyfødtes komplicerede første uge
14/03/2019 → 14/03/2019
4 elementer af Mediedækning
Presse/medie
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How Do Our Immune Systems Develop in the First Days of Life?
22/10/2020
6 elementer af Mediedækning
Presse/medie
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Secrets of early life revealed from less than half a teaspoon of blood
12/03/2019
1 element af Mediedækning
Presse/medie