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Publikationer 2008 2019

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Tidsskriftartikel
2019
Peripheral Nervous System Diseases
Type 1 Diabetes Mellitus
Creatine
Spectrum Analysis
Brain
19 Downloads (Pure)

Quantities of comorbidities affects physical, but not mental health related quality of life in type 1 diabetes with confirmed polyneuropathy

Wegeberg, A-M. L., Meldgaard, T., Hyldahl, S., Jakobsen, P. E., Drewes, A. M., Brock, B. & Brock, C., 15 feb. 2019, I : World Journal of Diabetes. 10, 2, s. 87-95 9 s.

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Polyneuropathies
Type 1 Diabetes Mellitus
Comorbidity
Mental Health
Quality of Life
2018

Abnormal neuronal response to rectal and anal stimuli in patients treated with primary radiotherapy for anal cancer

Haas, S., Faaborg, P., Gram, M., Lundby, L., Brock, C., Drewes, A. M., Laurberg, S., Krogh, K. & Christensen, P., 2018, I : Radiotherapy and Oncology. 128, 2, s. 369–374 6 s.

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3 Citationer (Scopus)
57 Downloads (Pure)
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Oxycodone
Naloxone
Constipation
Opioid Analgesics
Therapeutics
113 Downloads (Pure)

Medically induced labor: Epidural analgesia and women’s perceptions of pain in early labor

Jacobsen, L. K., Haslund, H., Brock, C. & Laursen, B. S., 2018, I : European Journal of Midwifery. 2, November, s. 1-7 7 s.

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Fil

Offset Analgesia and The Impact of Treatment with Oxycodone and Venlafaxine: A Placebo-Controlled, Randomized Trial in Healthy Volunteers

Olesen, A. E., Nissen, T. D., Nilsson, M., Lelic, D., Brock, C., Christrup, L. L. & Drewes, A. M., 1 dec. 2018, I : Basic and Clinical Pharmacology and Toxicology. 123, 6, s. 727-731 5 s.

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Oxycodone
Analgesia
Healthy Volunteers
Randomized Controlled Trials
Placebos

Pharmacological modulation of colorectal distension evoked potentials in conscious rats

Nissen, T. D., Brock, C., Lykkesfeldt, J., Lindström, E. & Hultin, L., 15 sep. 2018, I : Neuropharmacology. 140, s. 193-200 8 s.

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Evoked Potentials
Baclofen
Pharmacology
Clonidine
GABA-B Receptor Agonists
5 Citationer (Scopus)

Regional gastrointestinal contractility parameters using the wireless motility capsule: inter-observer reproducibility and influence of age, gender and study country

Farmer, A. D., Wegeberg, A-M. L., Brock, B., Hobson, A. R., Mohammed, S. D., Scott, S. M., Bruckner-Holt, C. E., Semler, J. R., Hasler, W. L., Hellström, P. M., Drewes, A. M. & Brock, C., 1 feb. 2018, I : Alimentary Pharmacology and Therapeutics. 47, 3, s. 391-400 10 s.

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Capsules
Stomach
Area Under Curve
Meals
Gastrointestinal Tract

Regional gastrointestinal pH profile is altered in patients with type 1 diabetes and peripheral neuropathy

Wegeberg, A-M. L., Brock, C., Brock, B., Farmer, A. D., Hobson, A. R., Semler, J. R. & Scott, S. M., 1 nov. 2018, I : Neurogastroenterology and Motility. 30, 11, s. 1-10 10 s., e13407.

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Peripheral Nervous System Diseases
Type 1 Diabetes Mellitus
Nausea
Gastroparesis
Pylorus
1 Citation (Scopus)

The impact of naloxegol on anal sphincter function - Using a human experimental model of opioid-induced bowel dysfunction

Grønlund, D., Poulsen, J. L., Krogh, K., Brock, C., Liao, D., Gregersen, H., Drewes, A. M. & Olesen, A. E., 30 maj 2018, I : European Journal of Pharmaceutical Sciences. 117, s. 187-192 6 s.

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Anal Canal
Opioid Analgesics
Theoretical Models
Oxycodone
Reflex

The patient burden of opioidinduced bowel dysfunction

Hyldahl, S., Grønlund, D., Drewes, A. & Brock, C., 2018, I : Clinical Practice (Therapy). 15, 4, s. 775-784 10 s.

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2017
2 Citationer (Scopus)

Acute physiological and electrical accentuation of vagal tone has no effect on pain or gastrointestinal motility in chronic pancreatitis

Juel, J., Brock, C., Olesen, S. S., Madzak, A., Farmer, A. D., Aziz, Q., Frøkjær, J. B. & Drewes, A. M., 2017, I : Journal of Pain Research. 10, s. 1347-1355 9 s.

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Åben adgang
Vagus Nerve Stimulation
Transcutaneous Electric Nerve Stimulation
Gastrointestinal Motility
Chronic Pancreatitis
Respiration
5 Citationer (Scopus)

Cardiac vagal tone, a non-invasive measure of parasympathetic tone, is a clinically relevant tool in Type 1 diabetes mellitus

Brock, C., Jessen, N. C., Brock, B., Jakobsen, P. E., Hansen, T. K., Rantanen, J. M., Riahi, S., Dimitrova, Y. K., Dons-Jensen, A., Aziz, Q., Drewes, A. M. & Farmer, A. D., 2017, I : Diabetic Medicine. 34, 10, s. 1428-1434 7 s.

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Type 1 Diabetes Mellitus
Heart Rate
Peripheral Nervous System Diseases
Healthy Volunteers
Electrocardiography
1 Citation (Scopus)

Influence of exercise on visceral pain: an explorative study in healthy volunteers

van Weerdenburg, L. J., Brock, C., Drewes, A. M., van Goor, H., de Vries, M. & Wilder-Smith, O. H., 2017, I : Journal of Pain Research. 10, s. 37-46 10 s.

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Åben adgang
Visceral Pain
Healthy Volunteers
Exercise
Pain
Pain Threshold
3 Citationer (Scopus)

Integrity of central nervous function in diabetes mellitus assessed by resting state EEG frequency analysis and source localization

Frøkjær, J. B., Graversen, C., Brock, C., Khodayari-Rostamabad, A., Olesen, S. S., Hansen, T. M., Søfteland, E., Simrén, M. & Drewes, A. M., 2017, I : Journal of Diabetes and its Complications. 31, 2, s. 400-406 7 s.

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Electroencephalography
Diabetes Mellitus
Wavelet Analysis
Parietal Lobe
Somatosensory Cortex
1 Citation (Scopus)

Prolonged-Release Oxycodone/Naloxone Improves Anal Sphincter Relaxation Compared to Oxycodone Plus Macrogol 3350

Poulsen, J. L., Brock, C., Grønlund, D., Liao, D., Gregersen, H., Krogh, K. & Drewes, A. M., 2017, I : Digestive Diseases and Sciences. 62, 11, s. 3156-3166 11 s.

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Oxycodone
Anal Canal
Naloxone
Opioid Analgesics
Symptom Assessment
3 Citationer (Scopus)

Transcutaneous cervical vagal nerve stimulation modulates cardiac vagal tone and tumor necrosis factor-alpha

Brock, C., Brock, B., Aziz, Q., Møller, H. J., Pfeiffer Jensen, M., Drewes, A. M. & Farmer, A. D., 2017, I : Neurogastroenterology and Motility. 29, 5, 4 s., e12999.

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6 Citationer (Scopus)

Type 1 diabetic patients with peripheral neuropathy have pan-enteric prolongation of gastrointestinal transit times and an altered caecal pH profile

Farmer, A. D., Pedersen, A. G., Brock, B., Jakobsen, P. E., Karmisholt, J., Mohammed, S. D., Scott, S. M., Drewes, A. M. & Brock, C., 2017, I : Diabetologia. 60, 4, s. 709-718 10 s.

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Gastrointestinal Transit
Peripheral Nervous System Diseases
Diabetic Neuropathies
Gastric Emptying
Neuroprotective Agents
2016
2 Citationer (Scopus)

Does catastrophic thinking enhance oesophageal pain sensitivity? An experimental investigation

Martel, M. O., Olesen, A. E., Jørgensen, D., Nielsen, L. M., Brock, C., Edwards, R. R. & Drewes, A. M., 2016, I : European Journal of Pain. 20, 8, s. 1214-1222 9 s.

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Catastrophization
Pain
Pain Threshold
Acids
Esophageal Diseases
3 Citationer (Scopus)

Does Sacral Nerve Stimulation Improve Continence Through Enhanced Sensitivity of the Anal Canal? A Pilot Study

Haas, S., Brock, C., Krogh, K., Gram, M., Lundby, L., Drewes, A. M. & Laurberg, S., nov. 2016, I : Diseases of the Colon and Rectum. 59, 11, s. 1039-1046 8 s.

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Fecal Incontinence
Anal Canal
Evoked Potentials
Afferent Pathways
Rectum
22 Citationer (Scopus)

Modulation of vagal tone enhances gastroduodenal motility and reduces somatic pain sensitivity

Frøkjaer, J. B., Bergmann, S., Brock, C., Madzak, A., Farmer, A. D., Ellrich, J. & Drewes, A. M., 2016, I : Neurogastroenterology and Motility. 28, 4, s. 592-598 7 s.

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Nociceptive Pain
Pain Threshold
Vagus Nerve Stimulation
Transcutaneous Electric Nerve Stimulation
Respiration
1 Citation (Scopus)

Neurophysiology and new techniques to assess esophageal sensory function: an update

Brock, C., McCallum, R. W., Gyawali, C. P., D Farmer, A., Frøkjaer, J. B., P McMahon, B. & Drewes, A. M., 2016, I : Annals of the New York Academy of Sciences. 1380, 1, s. 78-90 13 s.

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Neurophysiology
Esophagus
Nociception
Pain
Mucous Membrane
12 Citationer (Scopus)

Opioid-induced bowel dysfunction in healthy volunteers assessed with questionnaires and MRI

Nilsson, M., Poulsen, J. L., Brock, C., Sandberg, T. H., Gram, M., Frøkjær, J. B., Krogh, K. & Drewes, A. M., 2016, I : European Journal of Gastroenterology and Hepatology. 28, 5, s. 514-524 11 s.

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Opioid Analgesics
Oxycodone
Healthy Volunteers
Symptom Assessment
Constipation
1 Citation (Scopus)

Pharmacological and other treatment modalities for esophageal pain

Hoff, D. A. L., Brock, C., Farmer, A. D., Dickman, R., Ruffle, J. K., Shaker, A. & Drewes, A. M., 2016, I : Annals of the New York Academy of Sciences. 1380, 1, s. 58-66 9 s.

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Analgesics
Pharmacology
Pain
Proton Pump Inhibitors
Neurology
2 Citationer (Scopus)

Rectal Mechano-sensory Function in Patients with Carcinoid Diarrhea

Gregersen, T., Brock, C., Haase, A-M., Laurberg, S., Drewes, A., Gronbaek, H. & Krogh, K., 2016, I : Neurogastroenterology and Motility. 22, 2, s. 264-271 8 s.

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Åben adgang
Carcinoid Tumor
Diarrhea
Healthy Volunteers
Sensory Thresholds
Hot Temperature
1 Citation (Scopus)

Short-term oxycodone treatment does not affect electrogenic ion transport in isolated mucosa from the human rectosigmoid colon

Nilsson, M., Brock, C., Lykke Poulsen, J., Bindslev, N., Berner Hansen, M., Louring Christrup, L. & Drewes, A., 2016, I : Scandinavian Journal of Gastroenterology. 51, 5, s. 538-547 10 s.

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Oxycodone
Ion Transport
Opioid Analgesics
Colon
Mucous Membrane
16 Citationer (Scopus)

The Impact of Opioid Treatment on Regional Gastrointestinal Transit

Poulsen, J. L., Nilsson, M., Brock, C., Sandberg, T. H., Krogh, K. & Drewes, A. M., 2016, I : Neurogastroenterology and Motility. 22, 2, s. 282-291 10 s.

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Åben adgang
Gastrointestinal Transit
Opioid Analgesics
Oxycodone
Constipation
Therapeutics
2 Citationer (Scopus)

The sensory system of the esophagus - what do we know?

Brock, C., Gregersen, H., Gyawali, C. P., Lottrup, C., Furnari, M., Savarino, E., Novais, L., Frøkjaer, J. B., Bohr, S. & Drewes, A. M., 2016, I : Annals of the New York Academy of Sciences. 1380, 1, s. 91–103 13 s.

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Esophagus
Nociceptive Pain
Barrett Esophagus
Manometry
Research Personnel
2015
8 Citationer (Scopus)

Abnormal neuronal response to rectal and anal stimuli in patients with idiopathic fecal incontinence

Haas, S., Brock, C., Krogh, K., Gram, M., Lundby, L., Drewes, A. M. & Laurberg, S., 2015, I : Neurogastroenterology and Motility. 27, 7, s. 954-962 9 s.

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Fecal Incontinence
Anal Canal
Rectum
Brain
Proxy
7 Citationer (Scopus)
Lung Volume Measurements
Carbon Monoxide
Chronic Obstructive Pulmonary Disease
Gases
Body Mass Index

Opioid-induced bowel dysfunction

Olesen, A. E., Brock, C. & Drewes, A., 2015, I : Hospital Pharmacy Europe. 78

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Åben adgang
22 Citationer (Scopus)

Preliminary report: modulation of parasympathetic nervous system tone influences oesophageal pain hypersensitivity

Botha, C., Farmer, A. D., Nilsson, M., Brock, C., Gavrila, A. D., Drewes, A. M., Knowles, C. H. & Aziz, Q., 2015, I : Gut. 64, 4, s. 611-617

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Parasympathetic Nervous System
Hypersensitivity
Respiration
Pain
Acids
13 Citationer (Scopus)

Quantification and variability in colonic volume with a novel magnetic resonance imaging method

Nilsson, M., Sandberg, T. H., Poulsen, J. L., Gram, M., Frøkjær, J. B., Østergaard, L. R., Krogh, K., Brock, C. & Drewes, A., 2015, I : Neurogastroenterology and Motility. 27, 12, s. 1755-1763

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2 Citationer (Scopus)

Rapid balloon distension as a tool to study cortical processing of visceral sensations and pain

Lelic, D., Nissen, T. D., Brock, C., Aziz, Q. & Drewes, A. M., 2015, I : Neurogastroenterology and Motility. 27, 6, s. 832-840 9 s.

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Evoked Potentials
Visceral Pain
Pain
Brain
Pain Threshold
2014
13 Citationer (Scopus)

Association between visceral, cardiac and sensorimotor polyneuropathies in diabetes mellitus

Søfteland, E., Brock, C., Frøkjær, J. B., Brøgger, J., Madácsy, L., Gilja, O. H., Arendt-Nielsen, L., Simrén, M., Drewes, A. M. & Dimcevski, G., 2014, I : Journal of Diabetes and its Complications. 28, 3, s. 370-377 8 s.

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Åben adgang
Polyneuropathies
Diabetes Mellitus
Bone and Bones
Muscles
Skin
5 Citationer (Scopus)

Cortical evoked potentials in response to rapid balloon distension of the rectum and anal canal

Haas, S., Brock, C., Krogh, K., Gram, M., Nissen, T. D., Lundby, L., Laurberg, S. & Drewes, A. M., 20 apr. 2014, I : Neurogastroenterology and Motility. 26, 6, s. 862-873

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Åben adgang
Anal Canal
Evoked Potentials
Rectum
Sensory Thresholds
Muscles

Electrophysiology as a tool to unravel the origin of pancreatic pain

Lelic, D., Olesen, S. S., Graversen, C., Brock, C., Valeriani, M. & Drewes, A. M., 15 feb. 2014, I : World Journal of Gastrointestinal Pathophysiology. 5, 1, s. 33-39 7 s.

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Åben adgang
Electrophysiology
Pain
Chronic Pancreatitis
Electroencephalography
Brain
6 Citationer (Scopus)

Neurophysiology of the esophagus

Brock, C., Brokjaer, A., Drewes, A. M., Farmer, A. D., Frøkjaer, J. B., Gregersen, H. & Lottrup, C., sep. 2014, I : Annals of the New York Academy of Sciences. 1325, 1, s. 57-68 12 s.

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Neurophysiology
Esophagus
Brain
Esophageal Neoplasms
Evoked Potentials
7 Citationer (Scopus)

Pathophysiology of late anorectal dysfunction following external beam radiotherapy for prostate cancer

Petersen, S. E., Bregendahl, S., Langschwager, M., Laurberg, S., Brock, C., Drewes, A. M., Krogh, K., Høyer, M. & Lundby, L., 24 jun. 2014, I : Acta Oncologica. 53, 10, s. 1398-1404 7 s.

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Åben adgang
Prostatic Neoplasms
Radiotherapy
Mucous Membrane
Sigmoidoscopy
Wounds and Injuries
2 Citationer (Scopus)

Postprandial Plasma Glucose Response and Gastrointestinal Symptom Severity in Patients With Diabetic Gastroparesis

Olausson, E. A., Grundin, H., Isaksson, M., Brock, C., Drewes, A. M., Attvall, S. & Simrén, M., 2014, I : Journal of Diabetes Science and Technology. 8, 4, s. 881-888

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Åben adgang
Gastroparesis
Glucose
Plasmas
Meals
Gastric Emptying
10 Citationer (Scopus)

Rectal sensitivity in diabetes patients with symptoms of gastroparesis

Søfteland, E., Brock, C., Frøkjær, J. B., Simrén, M., Drewes, A. M. & Dimcevski, G., 2014, I : Journal of Diabetes Research. 2014, 8 s., 784841.

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Åben adgang
Gastroparesis
Stomach
Hot Temperature
Heart Rate
Sensation Disorders
6 Citationer (Scopus)

Reproducibility of psychophysics and electroencephalography during offset analgesia

Nilsson, M., Piasco, A., Nissen, T. D., Graversen, C., Gazerani, P., Lucas, M-F., Dahan, A., Drewes, A. M. & Brock, C., 2014, I : European Journal of Pain. 18, 6, s. 824-834 11 s.

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Psychophysics
Analgesia
Electroencephalography
Pain Perception
Pain
11 Citationer (Scopus)

Sacral nerve stimulation changes rectal sensitivity and biomechanical properties in patients with irritable bowel syndrome

Fassov, J., Brock, C., Lundby, L., Drewes, A. M., Gregersen, H., Buntzen, S., Laurberg, S. & Krogh, K., 2014, I : Neurogastroenterology and Motility. 26, 11, s. 1597-1604 8 s.

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Irritable Bowel Syndrome
Sensory Thresholds
Diarrhea
Constipation
Cross-Over Studies
16 Citationer (Scopus)

Sensitivity of quantitative sensory models to morphine analgesia in humans

Olesen, A. E., Brock, C., Sverrisdóttir, E., Larsen, I. M. & Drewes, A. M., 2014, I : Journal of Pain Research. 7, s. 717-726 10 s.

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Åben adgang
Analgesia
Morphine
Pain
Pressure
Opioid Analgesics
11 Citationer (Scopus)

The brain networks encoding visceral sensation in patients with gastrointestinal symptoms due to diabetic neuropathy

Lelic, D., Brock, C., Simrén, M., Frøkjaer, J. B., Søfteland, E., Dimcevski, G., Gregersen, H. & Drewes, A. M., 2014, I : Neurogastroenterology and Motility. 26, 1, s. 46-58 13 s.

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Åben adgang
Diabetic Neuropathies
Electric Stimulation
Esophagus
Diabetes Mellitus
Brain
19 Citationer (Scopus)

The Role of Pain Catastrophizing in Experimental Pain Perception

Kristiansen, F. L., Olesen, A. E., Brock, C., Gazerani, P., Petrini, L., Mogil, J. S. & Drewes, A. M., 2014, I : Pain Practice. 14, 3, s. E136-E145 10 s.

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Catastrophization
Pain Perception
Pain
2013
13 Citationer (Scopus)

A human experimental bone pain model

Andresen, T., Jensen, M. P., Brock, C., Drewes, A. & Arendt-Nielsen, L., 2013, I : Basic & Clinical Pharmacology & Toxicology. 112, 2, s. 116-123

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22 Citationer (Scopus)

Altered brain microstructure assessed by diffusion tensor imaging in patients with diabetes and gastrointestinal symptoms

Frøkjær, J. B., Andersen, L. W., Brock, C., Simrén, M., Ljungberg, M., Søfteland, E., Dimcevski, G., Yavarian, Y., Gregersen, H. & Drewes, A. M., mar. 2013, I : Diabetes Care. Supplement. 36, 3, s. 662-8 7 s.

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Diffusion Tensor Imaging
Diabetes Mellitus
Magnetic Resonance Spectroscopy
Central Nervous System
Brain
14 Citationer (Scopus)

Brain networks encoding rectal sensation in type 1 diabetes

Lelic, D., Brock, C., Søfteland, E., Frøkjær, J. B., Andresen, T., Simrén, M. & Drewes, A., 2013, I : Neuroscience. 237, s. 96-105

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8 Citationer (Scopus)

Central response to painful electrical esophageal stimulation in well-defined patients suffering from functional chest pain

Hoff, D. A. L., Krarup, A. L., Lelic, D., Olesen, S. S., Dimcevski, G., Hansen, T. M., Brock, C., Hatlebakk, J. G. & Drewes, A. M., 2013, I : Neurogastroenterology and Motility. 25, 11, s. e718-e727 10 s.

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Chest Pain
Electric Stimulation
Healthy Volunteers
Central Nervous System