Projekter pr. år
Personlig profil
Forskningsprofil
With a background as a veterinary surgeon and a PhD in human biology, I bring a unique multidisciplinary perspective to translational research, bridging clinical, academic, and life-science environments. My professional journey began with 11 years as a veterinary surgeon, which provided me with a strong foundation in pathophysiology and clinical problem-solving. This experience, combined with extensive academic training, has shaped a research career focused on the autonomic nervous system at the intersection of neurophysiology, diabetes, and gastroenterology.
As a full professor within the autonomic nervous system, I have established a state-of-the-art autonomic laboratory capable of capturing comprehensive sympathetic and parasympathetic profiles. This facility supports both mechanistic investigations and clinical trials, enabling the translation of fundamental insights into patient care. I have earned an internationally recognized reputation and status within this field. Finally, I have been selected as one of the emerging Talents from Aalborg University, known for my analytical mindset, collaborative leadership, and innovative approach to complex biomedical challenges.
At the Clinical Institute at Aalborg university, I am deeply involved in academic teaching and mentoring. I teach medical students at both Bachelor’s and Master’s levels and contribute to curriculum development and laboratory-based instruction. I have supervised 18 PhD students (five as principal supervisor), 19 Master’s students (eight as principal supervisor), and numerous undergraduate and postgraduate students across medicine, veterinary science, and the Master of Pain Management program. My commitment to teaching is further demonstrated through my involvement in examinations and mentoring across a broad range of health science disciplines.
Over the past decade, I have led and coordinated multiple investigator-initiated clinical trials examining the effects of vagal nerve stimulation on cardiac and gastrointestinal function, its anti-inflammatory mechanisms, and the role of GLP-1. I am currently initiating a new project investigating the anti-fibrotic and neuroprotective potential of finerenon in microvascular complications of diabetic autonomic neuropathy. These projects reflect a commitment to multidisciplinary collaboration, strategic trial design, and regulatory engagement, with a particular focus on defining valid clinical endpoints and advancing consensus in the field. I have served as sponsor for seven clinical trials, overseeing their design, implementation, and communication with regulatory authorities.
In addition to research and teaching, I hold several academic leadership roles. I have secured over €3.7 million in research funding as principal investigator and co-applicant and serve on the executive board of NEUROdiab. I am a faculty member in FNM Neurogastro and have served as a faculty advisor at the Office of Global Education at Harvard Medical School. My contributions to the scientific community include reviewing for international journals, organizing symposia and workshops on neurophysiology, translational medicine, diabetic neuropathy, and visceral pain, and previously serving as head of the National Advisory Board of the Danish Diabetes Academy.
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- 1 Lignende profiler
Samarbejde i de sidste fem år
Projekter
- 1 Igangværende
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Autonom neuropati hos patienter med mitochondriesygdom
Nielsen, S. R. (PI (principal investigator)), Frederiksen, A. L. (Supervisor), Pedersen, I. S. (Supervisor) & Brock, C. (Supervisor)
01/01/2022 → 07/07/2026
Projekter: Projekt › Ph.d.-projekt
Publikationer
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Barriers and new opportunities in developing effective therapies for diabetic neuropathy: International expert consensus recommendations
Brock, C., Andersen, H., Alibegovic, A. C., Andersen, S. T., Andreasen, L. J., Charles, M. H., Christensen, D. H., Drewes, A. M., Gall, M.-A., Gylfadottir, S. S., Hansen, C. S., Hecquet, S. K., Jensen, T. S., Karlsson, P., Knudsen, L. B., Lobato, C. B., Kufaishi, H., Maalmi, H., Mizrak, H. I. & Nilsen, K. B. & 15 flere, , mar. 2025, I: Diabetes Research and Clinical Practice. 221, 10 s., 112010.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil14 Downloads (Pure) -
Diabetic gastroenteropathy: a pan-alimentary complication
Kornum, D. S., Krogh, K., Keller, J., Malagelada, C., Drewes, A. M. & Brock, C., maj 2025, I: Diabetologia. 68, 5, s. 905-919 15 s.Publikation: Bidrag til tidsskrift › Review (oversigtsartikel) › peer review
Åben adgang -
Panenteric Transit Times and Contractile Activity in Diabetic Gastroenteropathy
Kornum, D. S., Brock, C., Okdahl, T., Bertoli, D., Kufaishi, H., Wegeberg, A. M., Høyer, K. L., Mark, E. B., Brock, B., Hansen, C. S., Knop, F. K., Drewes, A. M. & Krogh, K., 30 apr. 2025, I: Journal of Neurogastroenterology and Motility. 31, 2, s. 241-255 15 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Possible Glycemic Effects of Vagus Nerve Stimulation Evaluated by Continuous Glucose Monitoring in People with Diabetes and Autonomic Neuropathy: A Randomized, Sham-Controlled Trial
Kufaishi, H., Bertoli, D., Kornum, D. S., Ranjan, A. G., Nørgaard, K., Krogh, K., Brock, B., Okdahl, T., Frøkjær, J. B., Drewes, A. M., Brock, C., Krag Knop, F., Hansen, T. W., Hansen, C. S. & Rossing, P., 1 jan. 2025, I: Diabetes Technology & Therapeutics. 27, 1, s. 52-59 8 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Understanding the Impact of Diabetic Peripheral Neuropathy and Neuropathic Pain on Quality of Life and Mental Health in 6,960 People With Diabetes
Borbjerg, M. K., Wegeberg, A.-M., Nikontovic, A., Mørch, C. D., Arendt-Nielsen, L., Ejskjaer, N., Brock, C., Vestergaard, P. & Røikjer, J., 1 apr. 2025, I: Diabetes care. 48, 4, s. 588-595 8 s., dc242287.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
1 Citationer (Scopus)
Forskningsdatasæt
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Additional file 1 of Elevated levels of interleukin-12/23p40 may serve as a potential indicator of dysfunctional heart rate variability in type 2 diabetes
Ejskjaer, N. (Ophavsperson), Riahi, S. (Ophavsperson), Okdahl, T. (Ophavsperson), Brock, C. (Ophavsperson), St?rling, J. (Ophavsperson), Wegeberg, A. M. (Ophavsperson), Brock, B. (Ophavsperson) & Pociot, F. (Ophavsperson), Figshare, 2022
DOI: 10.6084/m9.figshare.17982814.v1, https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_Elevated_levels_of_interleukin-12_23p40_may_serve_as_a_potential_indicator_of_dysfunctional_heart_rate_variability_in_type_2_diabetes/17982814/1
Datasæt
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Elevated levels of interleukin-12/23p40 may serve as a potential indicator of dysfunctional heart rate variability in type 2 diabetes
Wegeberg, A. M. (Ophavsperson), Okdahl, T. (Ophavsperson), Riahi, S. (Ophavsperson), Ejskjaer, N. (Ophavsperson), Pociot, F. (Ophavsperson), Størling, J. (Ophavsperson), Brock, B. (Ophavsperson) & Brock, C. (Ophavsperson), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5782036, https://springernature.figshare.com/collections/Elevated_levels_of_interleukin-12_23p40_may_serve_as_a_potential_indicator_of_dysfunctional_heart_rate_variability_in_type_2_diabetes/5782036
Datasæt
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Elevated levels of interleukin-12/23p40 may serve as a potential indicator of dysfunctional heart rate variability in type 2 diabetes
Wegeberg, A. M. (Ophavsperson), Okdahl, T. (Ophavsperson), Riahi, S. (Ophavsperson), Ejskjaer, N. (Ophavsperson), Pociot, F. (Ophavsperson), Størling, J. (Ophavsperson), Brock, B. (Ophavsperson) & Brock, C. (Ophavsperson), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5782036.v1, https://springernature.figshare.com/collections/Elevated_levels_of_interleukin-12_23p40_may_serve_as_a_potential_indicator_of_dysfunctional_heart_rate_variability_in_type_2_diabetes/5782036/1
Datasæt
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Liraglutide accelerates colonic transit in people with type 1 diabetes and polyneuropathy: A randomised, double-blind, placebo-controlled trial
Wegeberg, A.-M. L. (Ophavsperson), Hansen, C. S. (Ophavsperson), Farmer, A. D. (Ophavsperson), Karmisholt, J. S. (Ophavsperson), Drewes, A. M. (Bidrager), Jakobsen, P. E. (Ophavsperson), Brock, B. (Ophavsperson) & Brock, C. (Ophavsperson), Sage Journals, 2020
DOI: 10.25384/sage.c.4975523, https://sage.figshare.com/collections/Liraglutide_accelerates_colonic_transit_in_people_with_type_1_diabetes_and_polyneuropathy_A_randomised_double-blind_placebo-controlled_trial/4975523
Datasæt
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sj-pdf-1-ueg-10.1177_2050640620925968 - Supplemental material for Liraglutide accelerates colonic transit in people with type 1 diabetes and polyneuropathy: A randomised, double-blind, placebo-controlled trial
Drewes, A. M. (Bidrager), Brock, B. (Ophavsperson), Hansen, C. S. (Ophavsperson), Brock, C. (Ophavsperson), Farmer, A. D. (Ophavsperson), Karmisholt, J. S. (Ophavsperson), Wegeberg, A.-M. L. (Ophavsperson) & Jakobsen, P. E. (Ophavsperson), Sage Journals, 2020
DOI: 10.25384/sage.12294305.v1, https://doi.org/10.25384%2Fsage.12294305.v1
Datasæt: Supplerende materiale
Presse/medier
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Kan nøglen til lindring for stress og depression ligge i vagusnerven?
20/01/2025
1 element af Mediedækning
Presse/medie
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Øjnene afslører nerveskader hos patienter med type 1-diabetes
23/11/2023
1 element af Mediedækning
Presse/medie
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Øjnene sladrer om skader på centralnervesystemet hos personer med diabetes
19/09/2023 → 20/09/2023
2 elementer af Mediedækning
Presse/medie
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Kronisk inflammation ved type 2-diabetes bidrager til risiko for komorbiditeter
13/01/2023 → 27/01/2023
2 elementer af Mediedækning
Presse/medie