Projekter pr. år
Personlig profil
Forskningsprofil
I am a researcher with one foot in the clinic in the Department of Hematology at Aalborg University Hospital. My research emerges from clinical challenges, and I am engaged in several epidemiological and biochemical studies of coagulation and hematological diseases, and an innovative project investigating effects of ketones in cancer treatment. My main research area is development of new, non-invasive diagnostics and monitoring of diseases and treatments by omics-analysis of the air we exhale.
My research in exhaled breath proteomics is inspired from my clinical work, where I often deal with acute medical conditions in fragile patients.
With +10 years of experience with collection and analysis of exhaled breath samples, I have demonstrated that the air we exhale contains endogenous proteins from a broad variety of biological processes in our bodies. I think of our exhaled breath as a biological sample, just like a blood sample, but with the great benefits of non-invasive collection (as we must breathe anyway) and potential for continuous sample collection.
I lead the Exhaled Breath Diagnostics and Monitoring research group (ExBreDia) in the Department of Hematology at Aalborg University hospital. The research group was established with a Clinical Emerging Investigator grant from the Novo Nordisk Foundation in 2024. As investigation of non-volatile organic compounds in the exhaled breath is still an emerging field of research, the research group focuses on method optimization and investigation of the potential for rapid diagnostics in various types of medical conditions to find the most promising paths to clinical implementation.
Throughout the years, I have been actively engaged with industrial and academic collaborators to improve exhaled breath collection and analysis, leading to advancements in equipment and methodologies opening a novel research avenue for identifying biomarkers with the potential to transform point-of-care diagnostics and monitoring. My ultimate research aim is the application of non-invasive exhaled breath precision diagnostic and monitoring methods for the benefit of both patients and society.
Ph.d.-vejledning
PhD main supervisor for Sophie Rex Christensen, 2025 -
PhD co-supervisor for Jesper Erik Karl Strandberg, 2020 -
PhD co-supervisor for Jennifer Bøgh, Department of Clinical Medicine, Århus University, 2024 -
Moderator of the PhD defence by Mia Solholt Godthaab Brath, 2024
PhD predefence chairman for Andreas Øvlisen, 2019 and Line Bjerrehave Nielsen, 2023
Undervisningsprofil
I teach medical students at master level. With PBL as take-off, I use cases from my own clinical practice in both case - and formal classes. I mainly cover lymphoproliferative diseases, anemia and acute hematological conditions.
I have been supervising several student projects, please see the up-loaded portfoli for furter information, and keep an eye on the project catalogue for projects from the ExBreDia group.
Administrativ profil
2024: Medstifter af Netværk for Kliniske Lektorer ved Aalborg Universitet, forperson for forskningsudvalget herunder.
Ekspertise relateret til FN’s Verdensmål
I 2015 blev FN's medlemslande enige om 17 Verdensmål til at bekæmpe fattigdom, beskytte planeten og sikre velstand for alle. Denne persons arbejde bidrager til følgende verdensmål:
Fingerprint
- 1 Lignende profiler
Samarbejde i de sidste fem år
Projekter
- 5 Igangværende
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Exhaled Breath Collector
Gade, I. L. (PI (principal investigator)), Rex Christensen, S. (CoI (co-investigator)), Rees, S. E. (CoI (co-investigator)) & Honoré, B. (CoI (co-investigator))
01/09/2025 → …
Projekter: Projekt › Andet
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Exploring exhaled breath biomarkers for non-invasive diagnostics showcased by stroke and pulmonary embolism
Gade, I. L. (PI (principal investigator)), Kjærgaard, B. (CoPI), Modrau, B. (CoPI), Rees, S. E. (CoI (co-investigator)) & Honoré, B. (CoPI)
01/02/2025 → …
Projekter: Projekt › Forskning
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NILEX: Non-invasive Diagnosis of Pulmonary Embolism by use of Biomarkers in Exhaled Breath
Gade, I. L. (PI (principal investigator)), Honoré, B. (CoPI), Krarup, A. L. (Projektdeltager), Roed, M. L. (Projektdeltager) & Kristensen, S. R. (CoPI)
01/02/2024 → …
Projekter: Projekt › Forskning
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Exhaled breath protein composition in patients
Gade, I. L. (PI (principal investigator)), Bennike, T. B. (PI (principal investigator)), Kristensen, S. R. (PI (principal investigator)) & Honoré, B. (PI (principal investigator))
01/02/2024 → …
Projekter: Projekt › Forskning
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NIPA: Non-invasive Diagnosis of Invasive Pulmonary Aspergillosis by use of Biomarkers in Exhaled Breath Condensate
Gade, I. L. (PI (principal investigator)) & Honoré, B. (CoI (co-investigator))
01/02/2023 → 31/01/2026
Projekter: Projekt › Forskning
Publikationer
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A systematic review of the exhaled breaths protein composition
Pedersen, J. L., Christensen, S. R., Bennike, T. B., Honoré, B. & Gade, I. L., 2025, Breath Summit 2025: Conference Programme and Book of Abstracts. Innsbruck, Austria, s. 177-178 1 s.Publikation: Bidrag til bog/antologi/rapport/konference proceeding › Konferenceabstrakt i proceeding › Forskning › peer review
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Detection of pathogenic DNA in exhaled breath condensate using Pneumocystis jirovecii as example
Christensen, S. R., Lundsted, D. H., Nørholt, D. H., Jensen, E., Wittrup, J. H., Abou-Harb, J., Stentoft, V. D. F. & Gade, I. L., 2025, Breath Summit 2025 : Conference Programme and Book of Abstracts. Innsbruck, Austria, s. 109-110 2 s.Publikation: Bidrag til bog/antologi/rapport/konference proceeding › Konferenceabstrakt i proceeding › Forskning › peer review
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Exhaled breath protein composition in patients hospitalised during the first wave of COVID-19
Gade, I. L., Bodilsen, J., Mariager, T., Hertz, S., Duerlund, L. S. S., Holm, C. K., Madsen, P. H., Bennike, T. B. & Honoré, B., 1 jul. 2025, I: Journal of Breath Research. 19, 3, 036008.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Forsøgsprotokollen
El-Galaly, T. C., Gade, I. L. & Jensen, P., 2025, Kliniske lægemiddelforsøg. Johnsen, S., Hansen, L. & Klokker, D. (red.). 1. udg. FADL's Forlag a/s, s. 32-42 11 s.Publikation: Bidrag til bog/antologi/rapport/konference proceeding › Bidrag til bog/antologi › Undervisning › peer review
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Increased contact system activity three months after starting combined oral contraceptives
Strandberg, J., Nybo, J., Gade, I. L., Palarasah, Y., Bladbjerg, E.-M. & Kristensen, S. R., sep. 2025, I: Thrombosis Research. 253, 5 s., 109428.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Aktiviteter
- 1 Konferenceoplæg
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Bottom-up proteomic analysis of the exhaled breath condensate from twenty-six individual healthy persons
Gade, I. L. (Foredragsholder), Bennike, T. B. (Foredragsholder), Kristensen, S. R. (Andet) & Honoré, B. (Andet)
14 jun. 2022Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
Presse/medier
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Udåndingsluft kan blive en værdifuld diagnostisk metode
Gade, I. L. & Kristensen, S. R.
14/04/2023
1 element af Mediedækning
Presse/medie
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Brok ved morgenkonferencen kan blive til bud på nye løsninger
Jørgensen , C. H., Driever, C. D., Gade, I. L., Huus Pedersen, S., Siggaard, L. D., Hviid, C. V. B. & Abood, A.A.-H.
14/04/2023
1 element af Mediedækning
Presse/medie
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Priser til fire lægelige talenter
Gade, I. L., Petersen, C. N., Holm, K. F. & Sørensen Bork, C.
02/11/2020
1 element af Mediedækning
Presse/medie
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Priser til fire lægelige ildsjæle
Holm, K. F., Petersen, C. N., Gade, I. L. & Sørensen Bork, C.
24/10/2020
1 element af Mediedækning
Presse/medie
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