Projekter pr. år
Personlig profil
Forskningsprofil
Our innate immune system is the first to interact with pathogens (e.g. bacteria and virus) and is central in protecting us from infections and determining the final outcome. This is especially true for the very young where the immune system (innate and adaptive) is immature, rendering them increasingly susceptible to infectious diseases. At the same time, unfavorable immune reactions can lead to autoimmune diseases with a significant negative impact. My research focus is to understand the development of the human immune system in early life, with a particular focus on the innate immune system, and as an extension of this understand how immune reactions lead to autoimmune diseases. The main methods I apply are OMICS (Big Data) with bioinformatics including machine learning strategies. The perspective is to facilitate better treatment strategies and diagnostic tools.
Full list of publications: http://scholar.google.com/citations?user=v_zRbfcAAAAJ
CV: https://www.linkedin.com/in/tubenn
Undervisningsprofil
I teach on all academic levels at the university, from 1st semester to PhD level. PBL is a central element in all my teaching activities, and I have attended a number of PBL- andcase-based workshops.
Main subjects:
- Biochemistry
- Eucaryotic cell biology
- Enzyme kinetics
- Bioinformatics
- Proteomics analysis
- Course for case cafilitators
Main methods:
- Lectures with 10-300 students, physical and online with ongoing assignments.
- Project supervision. individual and in groups with laboratory and bioinformatics elements.
- Facilitation of problem-based case learning.
Administrativ profil
- Semester coordinator 1st semester, Medicine/MedIS BA.
- Module Coordinator Molecular Biology, Medicine/MedIS BA.
- Union Representative (H-TR) for IDA at AAU SUND
Ph.d.-vejledning
- PhD Co-supervisor for Karen Mai Møllegaard (2021 - ), Laura Lind Throne Degn (2021 - )
- PhD assessment committe chairman Bartosz Laczek (2024), Tariq Abbas (2023), Guoqiang Ren (2022), Qiuyue Peng (2022), Anne Mette Frøbert Harbo (2022), Rocco Giordano (2021), Jonas Ellegaard Nielsen (2021)
- PhD Predefence chairman Amalie Elton Baisgaard (2024), Mikkel Eggert Thomsen (2024)
Ekspertise relateret til FN’s Verdensmål
I 2015 blev FN's medlemslande enige om 17 Verdensmål til at bekæmpe fattigdom, beskytte planeten og sikre velstand for alle. Denne persons arbejde bidrager til følgende verdensmål:
Uddannelse (Akademiske kvalifikationer)
Adjunktpædagogikum, Adjunktpædagogikum
1 jan. 2017 → 14 feb. 2019
Dimissionsdato: 14 feb. 2019
Postdoctoral researcher, The innate immune system and inflammation: Proteomics and bioinformatics, Harvard University
1 okt. 2015 → 31 mar. 2017
Postdoctoral resaercher, The innate immune system in inflammatory bowel diseases, Regional Hospital Southern Denmark
1 apr. 2014 → 31 mar. 2015
Eksterne ansættelser
External consultant, Biogenity
1 aug. 2024 → …
Adjunct Associate Professor in Inflammatory Diseases, University of Southern Denmark
1 apr. 2021 → 31 mar. 2026
Externally Affiliated Postdoctoral Researcher SteenLab Proteomics, Boston Children’s Hospital, Harvard Medical School
1 apr. 2017 → …
Emneord
- Biomedicin
- Protein Science
- Systems Biology based approaches using proteomic and metabolomic techniques
- immunology
- innate immune system
- Bioinformatics
- transcriptomics
- proteomics
- Medicin
- Protein Science
- Systems Biology based approaches using proteomic and metabolomic techniques
- immunology
- innate immune system
- Bioinformatics
- transcriptomics
- proteomics
- Kemi og Biovidenskab
- biochemistry
- enzymes
- metabolism
- hormones
Fingerprint
- 1 Lignende profiler
Samarbejde i de sidste fem år
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EPIC-HIPC: Systems Biology to Identify Biomarkers of Neonatal Vaccine Immunogenicity (EPIC-HIPC)
Bennike, T. B. (PI (principal investigator))
01/01/2016 → 01/01/2022
Projekter: Projekt › Forskning
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The innate immune system: Ontogeny and role in inflammatory diseases
Bennike, T. B. (PI (principal investigator))
Lundbeckfonden, A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal, Carlsbergfondet
01/01/2014 → …
Projekter: Projekt › Forskning
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BreathOMICS
Gade, I. L. (PI (principal investigator)), Bennike, T. B. (PI (principal investigator)), Kristensen, S. R. (PI (principal investigator)) & Honoré, B. (PI (principal investigator))
Projekter: Projekt › Forskning
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MassIVE: Re-analysis of publicly available proteomics datasets
Bennike, T. B. (PI (principal investigator))
20/10/2016 → 01/03/2019
Projekter: Projekt › Forskning
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TPIAT: Molecular markers of pancreatitis patients, pre- and post Total Pancreatectomy with Islet AutoTransplantation surgery
Bennike, T. B. (PI (principal investigator))
01/01/2016 → 11/04/2024
Projekter: Projekt › Forskning
Publikationer
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Dynamic molecular changes during the first week of human life follow a robust developmental trajectory
Lee, A. H., Shannon, C. P., Amenyogbe, N., Bennike, T. B., Diray-Arce, J., Idoko, O. T., Gill, E. E., Ben-Othman, R., Pomat, W. S., van Haren, S. D., Cao, K. A. L., Cox, M., Darboe, A., Falsafi, R., Ferrari, D., Harbeson, D. J., He, D., Bing, C., Hinshaw, S. J. & Ndure, J. & 24 flere, , 12 mar. 2019, I: Nature Communications. 10, 1, 14 s., 1092.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil140 Citationer (Scopus)134 Downloads (Pure) -
Advancing Inflammatory Bowel Disease Treatment by Targeting the Innate Immune System and Precision Drug Delivery
Kiilerich, K. F., Andresen, T., Darbani, B., Gregersen, L. H. K., Liljensøe, A., Bennike, T. B., Holm, R., Moeller, J. B. & Andersen, V., 11 jan. 2025, I: International Journal of Molecular Sciences . 26, 2, 575.Publikation: Bidrag til tidsskrift › Review (oversigtsartikel) › peer review
Åben adgangFil1 Citationer (Scopus)14 Downloads (Pure) -
Exhaled breath protein composition in patients hospitalized during the first wave of COVID-19
Gade, I. L., Bodilsen, J., Mariager, T., Hertz, S., Duerlund, L. S. S., Holm, C. K., Madsen, P. H., Bennike, T. B. & Honoré, B., 8 maj 2025, (E-pub ahead of print) I: Journal of Breath Research.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgang -
A clinical proteomics study of exhaled breath condensate and biomarkers for pulmonary embolism
Gade, I. L., Juul Riddersholm, S., Stilling-Vinther, T., Brøndum, R. F., Bennike, T. B. & Honoré, B., jan. 2024, I: Journal of Breath Research. 18, 1, 016007.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil3 Citationer (Scopus)89 Downloads (Pure) -
Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation
An, A. Y., Acton, E., Idoko, O. T., Shannon, C. P., Blimkie, T. M., Falsafi, R., Wariri, O., Imam, A., Dibbasey, T., Bennike, T. B., Smolen, K. K., Diray-Arce, J., Ben-Othman, R., Montante, S., Angelidou, A., Odumade, O. A., Martino, D., Tebbutt, S. J., Levy, O. & Steen, H. & 5 flere, , dec. 2024, I: EBioMedicine. 110, 105411.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil1 Citationer (Scopus)5 Downloads (Pure)
Forskningsdatasæt
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Additional file 1 of Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
Birkelund, S. (Ophavsperson), Bennike, T. B. (Ophavsperson), Kastaniegaard, K. (Ophavsperson), Lausen, M. (Ophavsperson), Poulsen, T. B. G. (Ophavsperson), Kragstrup, T. W. (Ophavsperson), Deleuran, B. W. (Ophavsperson), Christiansen, G. (Ophavsperson) & Stensballe, A. (Ophavsperson), Figshare, 6 aug. 2020
DOI: 10.6084/m9.figshare.12775188.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Proteomic_analysis_of_synovial_fluid_from_rheumatic_arthritis_and_spondyloarthritis_patients/12775188/1 og et link mere, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Proteomic_analysis_of_synovial_fluid_from_rheumatic_arthritis_and_spondyloarthritis_patients/12775188 (vis færre)
Datasæt
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Complement deposition on Chlamydia trachomatis
Bennike, T. B. (Ophavsperson), Nielsen, M. L. (Ophavsperson), Thomsen, M. E. (Ophavsperson), Christiansen, G. (Ophavsperson), Karred, N. (Ophavsperson), Stensballe, A. (Ophavsperson) & Birkelund, S. (Ophavsperson), PRoteomics IDEntifications Database (PRIDE), 26 maj 2020
https://www.ebi.ac.uk/pride/archive/projects/PXD019393
Datasæt
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Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
Birkelund, S. (Ophavsperson), Bennike, T. B. (Ophavsperson), Kastaniegaard, K. (Ophavsperson), Lausen, M. (Ophavsperson), Poulsen, T. B. G. (Ophavsperson), Kragstrup, T. W. (Ophavsperson), Deleuran, B. W. (Ophavsperson), Christiansen, G. (Ophavsperson) & Stensballe, A. (Ophavsperson), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5085102.v1, https://doi.org/10.6084%2Fm9.figshare.c.5085102.v1
Datasæt
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Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
Birkelund, S. (Ophavsperson), Bennike, T. B. (Ophavsperson), Kastaniegaard, K. (Ophavsperson), Lausen, M. (Ophavsperson), Poulsen, T. B. G. (Ophavsperson), Kragstrup, T. W. (Ophavsperson), Deleuran, B. W. (Ophavsperson), Christiansen, G. (Ophavsperson) & Stensballe, A. (Ophavsperson), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5085102, https://springernature.figshare.com/collections/Proteomic_analysis_of_synovial_fluid_from_rheumatic_arthritis_and_spondyloarthritis_patients/5085102
Datasæt
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Depleted Prefractionated Human Plasma for Data Independent Acquisition Spectral Library
Bennike, T. B. (Ophavsperson), Bellin, M. D. (Bidrager), Xuan, Y. (Bidrager), Stensballe, A. (Bidrager), Møller, F. T. (Bidrager), Beilman, G. (Bidrager), Levy, O. (Bidrager), Cruz-Monserrate, Z. (Bidrager), Andersen, V. (Bidrager), Steen, J. (Bidrager), Conwell, D. L. (Bidrager) & Steen, H. (Bidrager), PRoteomics IDEntifications Database (PRIDE), 18 apr. 2018
https://www.ebi.ac.uk/pride/archive/projects/PXD008163
Datasæt
Priser
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Svend Andersen Fondens Forsknings Talentpris
Bennike, T. B. (Modtager), 2025
Pris: Forsknings- uddannelses og innovationspriser
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Årets Underviser på Det Sundhedsvidenskabelige Fakultet
Bennike, T. B. (Modtager), 2025
Pris: Undervisningspriser
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Aktiviteter
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Ontogeny of the plasma proteome across the first week of human life
Bennike, T. B. (Foredragsholder)
18 okt. 2019Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
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Boston Children's Hospital
Bennike, T. B. (Gæsteforsker)
26 feb. 2025 → 3 mar. 2025Aktivitet: Gæsteophold ved andre institutioner
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OA07.03 | Insights from 3000 plasma proteins into the underlying biology of living with a Fontan Circulation and resulting Symptoms
Bennike, T. B. (Foredragsholder)
25 feb. 2025Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
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US Human Proteome Organization Conference 2025
Bennike, T. B. (Arrangør)
25 feb. 2025Aktivitet: Deltagelse i faglig begivenhed › Organisering af eller deltagelse i konference
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Aalborg R user meeting
Bennike, T. B. (Arrangør) & Brøndum, R. F. (Arrangør)
22 jan. 2025Aktivitet: Deltagelse i faglig begivenhed › Organisering af eller deltagelse i workshop, kursus, seminar, udstilling eller lignende
Presse/medier
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Bedre børnevaccination med Big Data: Ny forskning kortlægger nyfødtes komplicerede første uge
14/03/2019 → 14/03/2019
4 elementer af Mediedækning
Presse/medie
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How Do Our Immune Systems Develop in the First Days of Life?
22/10/2020
6 elementer af Mediedækning
Presse/medie
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Small babies, big data - Systems biology reveals babies' detailed developmental trajectory during week 1 of life
12/03/2019
1 element af Mediedækning
Presse/medie