In vivo enzyme evolution in filamentous fungi



This project involves the exploitation of natural mutation and the high selection pressures which develop in continuous flow culture systems, to obtain enzymes with specific new properties, such as altered substrate specificity or a reduced pH optimum. The project will focus on obtaining altered lipases and phytases from Fusarium venenatum and Aspergillus niger. (Marilyn Wiebe, Budi J. Hidayat, Niels T. Eriksen, Eva I. Petersen)
Effektiv start/slut dato01/01/200231/12/2005


  • 2 Tidsskriftartikel

Phosphate-limited continuous flow cultures of Fusarium venenatum A3/5 and production of acid phosphatase

Hidayat, B. J., Wiebe, M. G. & Eriksen, N. T., 5 mar. 2007, I : Enzyme and Microbial Technology. 40, 4, s. 902-907

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

1 Citationer (Scopus)

Acid phosphatase production by Aspergillus niger N402A in continuous flow culture

Hidayat, BJ., Eriksen, N. T. & Wiebe, MG., 2006, I : FEMS Microbiology Letters. 254, 2, s. 324-331

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

13 Citationer (Scopus)