A Functional Variant of the Serotonin Transporter Gene (SLC6A4) Moderates Impulsive Choice in Attention-Deficit/Hyperactivity Disorder Boys and Siblings

Edmund J S Sonuga-Barke; Robert Kumsta; Wolff Schlotz; Jessica Lasky-Su; Rafaela Marco; Ana Miranda; Fernando Mulas; Robert D Oades; Tobias Banaschewski; Ueli Mueller; Penny Andreou; Hanna Christiansen; Isabel Gabriels; Henrik Uebel; Jonna Kuntsi; Barbara Franke; Jan Buitelaar; Richard Ebstein; Michael Gill; Richard Anney; Herbert Roeyers; Aribert Rothenberger; Joseph Sergeant; Hans Christoph Steinhausen; Philip Asherson; Stephen V Faraone

doi:10.1016/j.biopsych.2011.01.040

A Functional Variant of the Serotonin Transporter Gene (SLC6A4) Moderates Impulsive Choice in Attention-Deficit/Hyperactivity Disorder Boys and Siblings

Edmund J S Sonuga-Barke, Robert Kumsta, Wolff Schlotz, Jessica Lasky-Su, Rafaela Marco, Ana Miranda, Fernando Mulas, Robert D Oades, Tobias Banaschewski, Ueli Mueller, Penny Andreou, Hanna Christiansen, Isabel Gabriels, Henrik Uebel, Jonna Kuntsi, Barbara Franke, Jan Buitelaar, Richard Ebstein, Michael Gill, Richard AnneyHerbert Roeyers, Aribert Rothenberger, Joseph Sergeant, Hans Christoph Steinhausen, Philip Asherson, Stephen V Faraone

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

44 Citationer (Scopus)

Abstract

Impulsive drive for immediate reward (IDIR) and delay aversion are dissociable elements of the preference for immediate over delayed rewards seen in attention-deficit/hyperactivity disorder (ADHD). We hypothesized that IDIR would be associated with dopamine regulating genes and delay aversion would be associated with serotonin-regulating genes.

Originalsprog	Engelsk
Tidsskrift	Biological Psychiatry
Vol/bind	70
Sider (fra-til)	230-6
Antal sider	7
ISSN	0006-3223
DOI	https://doi.org/10.1016/j.biopsych.2011.01.040
Status	Udgivet - 1 aug. 2011
Udgivet eksternt	Ja

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10.1016/j.biopsych.2011.01.040

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Sonuga-Barke, E. J. S., Kumsta, R., Schlotz, W., Lasky-Su, J., Marco, R., Miranda, A., Mulas, F., Oades, R. D., Banaschewski, T., Mueller, U., Andreou, P., Christiansen, H., Gabriels, I., Uebel, H., Kuntsi, J., Franke, B., Buitelaar, J., Ebstein, R., Gill, M., ... Faraone, S. V. (2011). A Functional Variant of the Serotonin Transporter Gene (SLC6A4) Moderates Impulsive Choice in Attention-Deficit/Hyperactivity Disorder Boys and Siblings. Biological Psychiatry, 70, 230-6. https://doi.org/10.1016/j.biopsych.2011.01.040

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title = "A Functional Variant of the Serotonin Transporter Gene (SLC6A4) Moderates Impulsive Choice in Attention-Deficit/Hyperactivity Disorder Boys and Siblings",

abstract = "Impulsive drive for immediate reward (IDIR) and delay aversion are dissociable elements of the preference for immediate over delayed rewards seen in attention-deficit/hyperactivity disorder (ADHD). We hypothesized that IDIR would be associated with dopamine regulating genes and delay aversion would be associated with serotonin-regulating genes.",

author = "Sonuga-Barke, {Edmund J S} and Robert Kumsta and Wolff Schlotz and Jessica Lasky-Su and Rafaela Marco and Ana Miranda and Fernando Mulas and Oades, {Robert D} and Tobias Banaschewski and Ueli Mueller and Penny Andreou and Hanna Christiansen and Isabel Gabriels and Henrik Uebel and Jonna Kuntsi and Barbara Franke and Jan Buitelaar and Richard Ebstein and Michael Gill and Richard Anney and Herbert Roeyers and Aribert Rothenberger and Joseph Sergeant and Steinhausen, {Hans Christoph} and Philip Asherson and Faraone, {Stephen V}",

year = "2011",

month = aug,

day = "1",

doi = "10.1016/j.biopsych.2011.01.040",

language = "English",

volume = "70",

pages = "230--6",

journal = "Biological Psychiatry",

issn = "0006-3223",

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Sonuga-Barke, EJS, Kumsta, R, Schlotz, W, Lasky-Su, J, Marco, R, Miranda, A, Mulas, F, Oades, RD, Banaschewski, T, Mueller, U, Andreou, P, Christiansen, H, Gabriels, I, Uebel, H, Kuntsi, J, Franke, B, Buitelaar, J, Ebstein, R, Gill, M, Anney, R, Roeyers, H, Rothenberger, A, Sergeant, J, Steinhausen, HC, Asherson, P & Faraone, SV 2011, 'A Functional Variant of the Serotonin Transporter Gene (SLC6A4) Moderates Impulsive Choice in Attention-Deficit/Hyperactivity Disorder Boys and Siblings', Biological Psychiatry, bind 70, s. 230-6. https://doi.org/10.1016/j.biopsych.2011.01.040

TY - JOUR

T1 - A Functional Variant of the Serotonin Transporter Gene (SLC6A4) Moderates Impulsive Choice in Attention-Deficit/Hyperactivity Disorder Boys and Siblings

AU - Sonuga-Barke, Edmund J S

AU - Kumsta, Robert

AU - Schlotz, Wolff

AU - Lasky-Su, Jessica

AU - Marco, Rafaela

AU - Miranda, Ana

AU - Mulas, Fernando

AU - Oades, Robert D

AU - Banaschewski, Tobias

AU - Mueller, Ueli

AU - Andreou, Penny

AU - Christiansen, Hanna

AU - Gabriels, Isabel

AU - Uebel, Henrik

AU - Kuntsi, Jonna

AU - Franke, Barbara

AU - Buitelaar, Jan

AU - Ebstein, Richard

AU - Gill, Michael

AU - Anney, Richard

AU - Roeyers, Herbert

AU - Rothenberger, Aribert

AU - Sergeant, Joseph

AU - Steinhausen, Hans Christoph

AU - Asherson, Philip

AU - Faraone, Stephen V

PY - 2011/8/1

Y1 - 2011/8/1

N2 - Impulsive drive for immediate reward (IDIR) and delay aversion are dissociable elements of the preference for immediate over delayed rewards seen in attention-deficit/hyperactivity disorder (ADHD). We hypothesized that IDIR would be associated with dopamine regulating genes and delay aversion would be associated with serotonin-regulating genes.

AB - Impulsive drive for immediate reward (IDIR) and delay aversion are dissociable elements of the preference for immediate over delayed rewards seen in attention-deficit/hyperactivity disorder (ADHD). We hypothesized that IDIR would be associated with dopamine regulating genes and delay aversion would be associated with serotonin-regulating genes.

U2 - 10.1016/j.biopsych.2011.01.040

DO - 10.1016/j.biopsych.2011.01.040

M3 - Journal article

SN - 0006-3223

VL - 70

SP - 230

EP - 236

JO - Biological Psychiatry

JF - Biological Psychiatry

ER -

A Functional Variant of the Serotonin Transporter Gene (SLC6A4) Moderates Impulsive Choice in Attention-Deficit/Hyperactivity Disorder Boys and Siblings

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