A large-scale, consortium-based genomewide association study of asthma

Miriam F Moffatt, Ivo G Gut, Florence Demenais, David P Strachan, Emmanuelle Bouzigon, Simon Heath, Erika von Mutius, Martin Farrall, Mark Lathrop, William O C M Cookson, GABRIEL Consortium, Torben Sigsgaard, Vivi Schlünssen, Ioannis Basinas, Øyvind Omland

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1602 Citationer (Scopus)

Abstract

Susceptibility to asthma is influenced by genes and environment; implicated genes may indicate pathways for therapeutic intervention. Genetic risk factors may be useful in identifying subtypes of asthma and determining whether intermediate phenotypes, such as elevation of the total serum IgE level, are causally linked to disease.
OriginalsprogEngelsk
TidsskriftThe New England Journal of Medicine
Vol/bind363
Sider (fra-til)1211-21
Antal sider11
ISSN0028-4793
DOI
StatusUdgivet - 23 sep. 2010
Udgivet eksterntJa

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