By the increase of the penetration of power-electronic-based (PE-based) units, such as wind turbines and PV systems, many features of those power systems, such as stability, security, and protection, have been changed. In this paper, the security of electrical grids with high wind turbines penetration is discussed. To do so, first, an overview of the power systems’ security assessment is presented. Based on that, stability and security challenges introduced by increasing the penetration of wind turbines in power systems are studied, and a new guideline for the security assessment of the PE-based power systems is proposed. Simulation results for the IEEE 39-bus test system show that the proposed security guideline is necessary for PE-based power systems, as the conventional security assessments may not be able to indicate its security status properly.