With the aim to increase today's low retrofitting rate and thus decrease the currently rising energy consumption of the building sector, this work proposes a novel renovation concept for schools. Therefore, two components, double skin facade (DSF) and diffuse ceiling ventilation (DCV), are combined with an exhaust ventilation system, providing an alternative to a traditional renovation where windows are replaced, the external wall is insulated and a balanced ventilation system is installed. Further, based on a Danish case study classroom, different configurations of the novel system, with varying glazing properties and DSF cavity thicknesses are compared against a range of traditional renovations through building performance simulation using IDA-ICE. The results indicate that the new system can achieve up to 11% lower total primary energy consumption as the best traditional renovation while achieving an equal indoor environmental quality and therefore offering designers and engineers a competitive alternative for school renovation projects. Additionally, employing a sensitivity analysis, it could be demonstrated for the primary energy consumption and the global thermal comfort that the glazing (number of panes and physical properties) has a superior influence on the novel system compared to the cavity thickness.