An Untargeted Metabolomics Survey from a Perturbation Model of Nitrogen Transformation in a Tropical Wastewater Community

Rasmus Hansen Kirkegaard, Anisa Angel Cokro, Shivshankar Umashankar, Victor Nesati, Sanjay Swarup, Per Halkjær Nielsen, Rohan Williams, Stefan Wuertz

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Abstract

In order to understand metabolic changes occurring during nitrogen transformation in a complex wastewater community, we conducted a metabolome time series study on a volume of freshly sourced, anoxic activated sludge, studying metabolic changes associated with the transition from anoxic to aerobic states. We develop analytic procedures for identifying reliable mass features that are modulated over the time, and are significantly correlated with shifts in physiochemical states. Our methods are widely applicable, and point towards to development of an eco-systems biology approach suitable for the targeted investigation of bioprocesses associated with engineered ecosystems.


OriginalsprogEngelsk
Publikationsdato2013
StatusUdgivet - 2013
BegivenhedMicrobial Ecology and Water Engineering 2013 - Ann Arbor, Michigan, USA
Varighed: 7 jul. 201310 jul. 2013
Konferencens nummer: 5

Konference

KonferenceMicrobial Ecology and Water Engineering 2013
Nummer5
Land/OmrådeUSA
ByAnn Arbor, Michigan
Periode07/07/201310/07/2013

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