TY - JOUR
T1 - Asymptomatic Right Atrial Thrombosis After Acute Lymphoblastic Leukemia Treatment
AU - Jarvis, Kirsten B
AU - Andersson, Nadine G
AU - Giertz, Mia
AU - Järvelä, Liisa
AU - Lindinger, Olle
AU - Långström, Satu
AU - Niinimäki, Riitta
AU - Palmu, Sauli
AU - Trakymiene, Sonata S
AU - Tuckuviene, Ruta
AU - Vepsäläinen, Kaisa
AU - Ranta, Susanna
AU - Frisk, Tony
N1 - Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2021/5
Y1 - 2021/5
N2 - Right atrial thrombosis is a rare, but potentially serious complication of acute lymphoblastic leukemia treatment. We conducted a retrospective multicenter study to assess the incidence, treatment, and outcome of asymptomatic right atrial thrombosis detected at routine echocardiography of children after acute lymphoblastic leukemia treatment in the Nordic and Baltic countries. Eleven (2.7%, 95% confidence interval, 1.4-4.9) of 406 patients had asymptomatic right atrial thrombosis, ranging from 10 to 25 mm at detection. Three patients were treated with anticoagulation. None of the thromboses affected cardiac function, and they showed neither sign of progress nor spontaneous or treatment-related regress at follow-up.
AB - Right atrial thrombosis is a rare, but potentially serious complication of acute lymphoblastic leukemia treatment. We conducted a retrospective multicenter study to assess the incidence, treatment, and outcome of asymptomatic right atrial thrombosis detected at routine echocardiography of children after acute lymphoblastic leukemia treatment in the Nordic and Baltic countries. Eleven (2.7%, 95% confidence interval, 1.4-4.9) of 406 patients had asymptomatic right atrial thrombosis, ranging from 10 to 25 mm at detection. Three patients were treated with anticoagulation. None of the thromboses affected cardiac function, and they showed neither sign of progress nor spontaneous or treatment-related regress at follow-up.
KW - acute lymphoblastic leukemia
KW - central venous catheter
KW - thrombosis
UR - http://www.scopus.com/inward/record.url?scp=85105604815&partnerID=8YFLogxK
U2 - 10.1097/MPH.0000000000001848
DO - 10.1097/MPH.0000000000001848
M3 - Journal article
C2 - 32555028
SN - 1077-4114
VL - 43
SP - e564-e566
JO - Journal of Pediatric Hematology/Oncology
JF - Journal of Pediatric Hematology/Oncology
IS - 4
ER -