Abstract
Venous blood is a convenient source of circulating extracellular vesicles (EVs). However, blood sampling requires authorized personnel and immediate purification of the vesicles. The present study demonstrate that intact EVs can in fact be obtained from dried blood card samples (or dried blood spots; DBS), which can be prepared by unauthorized personnel, or even at home by the user and shipped by regular mail. Intact EVs can be detected in extracts from dried blood spot samples even after prolonged storage.
Being able to isolate and characterize small EVs from DBS opens up a number of new opportunities such as monitoring of disease, e.g. progression of cancer and response to treatment, only with involvement of a lab technician and responsible clinician.
Being able to isolate and characterize small EVs from DBS opens up a number of new opportunities such as monitoring of disease, e.g. progression of cancer and response to treatment, only with involvement of a lab technician and responsible clinician.
Originalsprog | Engelsk |
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Publikationsdato | 2018 |
Status | Udgivet - 2018 |
Begivenhed | Danish IP Fair 2018 - Industriens Hus, København, Danmark Varighed: 29 maj 2018 → 29 maj 2018 https://dipfair2018.b2match.io/ |
Konference
Konference | Danish IP Fair 2018 |
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Lokation | Industriens Hus |
Land/Område | Danmark |
By | København |
Periode | 29/05/2018 → 29/05/2018 |
Internetadresse |