Carnitine Palmitoyl Transferase 1 – a Potential Target to Restore Dysregulated Metabolism in Neurodegenerative Diseases?: based on in vivo models mimicking Amyotrophic Lateral Sclerosis, Parkinson's Disease and Mutiple Sclerosis

Michael Trabjerg

doi:10.5278/vbn.phd.med.00136

Carnitine Palmitoyl Transferase 1 – a Potential Target to Restore Dysregulated Metabolism in Neurodegenerative Diseases? based on in vivo models mimicking Amyotrophic Lateral Sclerosis, Parkinson's Disease and Mutiple Sclerosis

Bidragets oversatte titel: Carnitine Palmitoyl Transferase 1 – et potentielt target til at revertere dysreguleret metabolisme i neurodegenerative sygdomme?: baseret på in vivo modeller for Amyotrofisk Lateral Sclerose, Parkinson’s Sygdom og Multiple Sclerose

Michael Trabjerg

Publikation: Ph.d.-afhandling

300 Downloads (Pure)

Bidragets oversatte titel	Carnitine Palmitoyl Transferase 1 – et potentielt target til at revertere dysreguleret metabolisme i neurodegenerative sygdomme?: baseret på in vivo modeller for Amyotrofisk Lateral Sclerose, Parkinson’s Sygdom og Multiple Sclerose
Originalsprog	Engelsk
Vejledere	Nieland, John Dirk, Hovedvejleder
Udgiver	Aalborg Universitetsforlag
ISBN'er, elektronisk	978-87-7210-851-3
DOI	https://doi.org/10.5278/vbn.phd.med.00136
Status	Udgivet - 2020

Bibliografisk note

PhD supervisor:
Associate Professor John Dirk Vestergaard Nieland, Aalborg University

Adgang til dokumentet

10.5278/vbn.phd.med.00136

PHD_MT_E_pdfForlagets udgivne version, 2,94 MB

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1 Afsluttet

The role of lipid metabolism in central nervous system diseases: evidence from toxic- and transgenic in vivo models
Trabjerg, M. (PI (principal investigator))
01/11/2017 → 01/12/2020
Projekter: Projekt › Forskning

3 Tidsskriftartikel
3 Konferenceabstrakt i tidsskrift
1 Konferenceabstrakt til konference
1 Poster

Downregulating carnitine palmitoyl transferase 1 affects disease progression in the SOD1 G93A mouse model of ALS
Trabjerg, M. S., Andersen, D. C., Huntjens, P., Oklinski, K. E., Bolther, L., Hald, J. L., Baisgaard, A. E., Mørk, K., Warming, N., Kullab, U. B., Kroese, L. J., Pritchard, C. E. J., Huijbers, I. J. & Nieland, J. D. V., 30 apr. 2021, I: Communications Biology. 4, 1, 509.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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17 Citationer (Scopus)

144 Downloads (Pure)
Dysregulation of metabolic pathways by carnitine palmitoyl-transferase 1 plays a key role in central nervous system disorders: experimental evidence based on animal models
Trabjerg, M. S., Mørkholt, A. S., Lichota, J., Oklinski, M. K. E., Andersen, D. C., Jønsson, K., Mørk, K., Skjønnemand, M.-L. N., Kroese, L. J., Pritchard, C. E. J., Huijbers, I. J., Gazerani, P., Corthals, A. & Nieland, J. D. V., 24 sep. 2020, I: Scientific Reports. 10, 1, 15583.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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12 Citationer (Scopus)

132 Downloads (Pure)
CPT1A plays a key role in the development and treatment of multiple sclerosis and experimental autoimmune encephalomyelitis
Mørkholt, A. S., Trabjerg, M. S., Oklinski, M. K. E., Bolther, L., Kroese, L. J., Pritchard, C. E. J., Huijbers, I. J. & Nieland, J. D. V., 16 sep. 2019, I: Scientific Reports. 9, 1, 13299.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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16 Citationer (Scopus)

149 Downloads (Pure)

Citationsformater

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title = "Carnitine Palmitoyl Transferase 1 – a Potential Target to Restore Dysregulated Metabolism in Neurodegenerative Diseases?: based on in vivo models mimicking Amyotrophic Lateral Sclerosis, Parkinson's Disease and Mutiple Sclerosis",

author = "Michael Trabjerg",

note = "PhD supervisor: Associate Professor John Dirk Vestergaard Nieland, Aalborg University",

year = "2020",

doi = "10.5278/vbn.phd.med.00136",

language = "English",

series = "Aalborg Universitet. Det Sundhedsvidenskabelige Fakultet. Ph.D.-Serien",

publisher = "Aalborg Universitetsforlag",

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T2 - based on in vivo models mimicking Amyotrophic Lateral Sclerosis, Parkinson's Disease and Mutiple Sclerosis

AU - Trabjerg, Michael

N1 - PhD supervisor: Associate Professor John Dirk Vestergaard Nieland, Aalborg University

PY - 2020

Y1 - 2020

U2 - 10.5278/vbn.phd.med.00136

DO - 10.5278/vbn.phd.med.00136

M3 - PhD thesis

T3 - Aalborg Universitet. Det Sundhedsvidenskabelige Fakultet. Ph.D.-Serien

PB - Aalborg Universitetsforlag

ER -

Carnitine Palmitoyl Transferase 1 – a Potential Target to Restore Dysregulated Metabolism in Neurodegenerative Diseases? based on in vivo models mimicking Amyotrophic Lateral Sclerosis, Parkinson's Disease and Mutiple Sclerosis

Bibliografisk note

Adgang til dokumentet

AUB Link

Projekter

The role of lipid metabolism in central nervous system diseases: evidence from toxic- and transgenic in vivo models

Publikation

Downregulating carnitine palmitoyl transferase 1 affects disease progression in the SOD1 G93A mouse model of ALS

Dysregulation of metabolic pathways by carnitine palmitoyl-transferase 1 plays a key role in central nervous system disorders: experimental evidence based on animal models

CPT1A plays a key role in the development and treatment of multiple sclerosis and experimental autoimmune encephalomyelitis

Citationsformater