TY - JOUR
T1 - Characterization of Eight Novel Spiroleptosphols from Fusarium avenaceum
AU - Westphal, Klaus Ringsborg
AU - Werner, Manuela Ilse Helga
AU - Nielsen, Katrine Amalie Hamborg
AU - Sørensen, Jens Laurids
AU - Andrushchenko, Valery
AU - Winde, Jacob
AU - Hertz, Morten
AU - Jensen, Mikkel Astrup
AU - Mortensen, Mathilde Lauge
AU - Bour, Petr
AU - Sondergaard, Teis Esben
AU - Wimmer, Reinhard
PY - 2019/9/26
Y1 - 2019/9/26
N2 - Chemical analyses of Fusarium avenaceum grown on banana medium resulted in eight novel spiroleptosphols, T1, T2 and U–Z (1–8). The structures were elucidated by a combination of high-resolution mass spectrometric data and 1- and 2-D NMR experiments. The relative stereochemistry was assigned by 1H coupling and NOESY/ROESY experiments. Absolute stereochemistry establishedfor 7 by vibrational circular dichroism was found analogous to that of the putative polyketide spiroleptosphol from Leptosphaeria doliolum.
AB - Chemical analyses of Fusarium avenaceum grown on banana medium resulted in eight novel spiroleptosphols, T1, T2 and U–Z (1–8). The structures were elucidated by a combination of high-resolution mass spectrometric data and 1- and 2-D NMR experiments. The relative stereochemistry was assigned by 1H coupling and NOESY/ROESY experiments. Absolute stereochemistry establishedfor 7 by vibrational circular dichroism was found analogous to that of the putative polyketide spiroleptosphol from Leptosphaeria doliolum.
KW - Spiroleptosphol
KW - Secondary metabolites
KW - Polyketides
KW - Polyketide synthases
KW - PKS
KW - Fusarium avenaceum
UR - http://www.scopus.com/inward/record.url?scp=85072692861&partnerID=8YFLogxK
U2 - 10.3390/molecules24193498
DO - 10.3390/molecules24193498
M3 - Journal article
SN - 1420-3049
VL - 24
JO - Molecules
JF - Molecules
IS - 19
M1 - 3498
ER -