TY - JOUR
T1 - Chiropractic spinal manipulation alters TMS induced I-wave excitability and shortens the cortical silent period
AU - Haavik, Heidi
AU - Niazi, Imran Khan
AU - Jochumsen, Mads
AU - Uginčius, Paulius
AU - Sebik, Oğuz
AU - Yılmaz, Gizem
AU - Navid, Muhammad Samran
AU - Özyurt, Mustafa Görkem
AU - Türker, Kemal S.
N1 - Copyright © 2018 Elsevier Ltd. All rights reserved.
PY - 2018/10/1
Y1 - 2018/10/1
N2 - The objective of this study was to construct peristimulus time histogram (PSTH) and peristimulus frequencygram (PSF) using single motor unit recordings to further characterize the previously documented immediate sensorimotor effects of spinal manipulation. Single pulse transcranial magnetic stimulation (TMS) via a double cone coil over the tibialis anterior (TA) motor area during weak isometric dorsiflexion of the foot was used on two different days in random order; pre/post spinal manipulation (in eighteen subjects) and pre/post a control (in twelve subjects) condition. TA electromyography (EMG) was recorded with surface and intramuscular fine wire electrodes. Three subjects also received sham double cone coil TMS pre and post a spinal manipulation intervention. From the averaged surface EMG data cortical silent periods (CSP) were constructed and analysed. Twenty-one single motor units were identified for the spinal manipulation intervention and twelve single motor units were identified for the control intervention. Following spinal manipulations there was a shortening of the silent period and an increase in the single unit I-wave amplitude. No changes were observed following the control condition. The results provide evidence that spinal manipulation reduces the TMS-induced cortical silent period and increases low threshold motoneurone excitability in the lower limb muscle. These finding may have important clinical implications as they provide support that spinal manipulation can be used to strengthen muscles. This could be followed up on populations that have reduced muscle strength, such as stroke victims.
AB - The objective of this study was to construct peristimulus time histogram (PSTH) and peristimulus frequencygram (PSF) using single motor unit recordings to further characterize the previously documented immediate sensorimotor effects of spinal manipulation. Single pulse transcranial magnetic stimulation (TMS) via a double cone coil over the tibialis anterior (TA) motor area during weak isometric dorsiflexion of the foot was used on two different days in random order; pre/post spinal manipulation (in eighteen subjects) and pre/post a control (in twelve subjects) condition. TA electromyography (EMG) was recorded with surface and intramuscular fine wire electrodes. Three subjects also received sham double cone coil TMS pre and post a spinal manipulation intervention. From the averaged surface EMG data cortical silent periods (CSP) were constructed and analysed. Twenty-one single motor units were identified for the spinal manipulation intervention and twelve single motor units were identified for the control intervention. Following spinal manipulations there was a shortening of the silent period and an increase in the single unit I-wave amplitude. No changes were observed following the control condition. The results provide evidence that spinal manipulation reduces the TMS-induced cortical silent period and increases low threshold motoneurone excitability in the lower limb muscle. These finding may have important clinical implications as they provide support that spinal manipulation can be used to strengthen muscles. This could be followed up on populations that have reduced muscle strength, such as stroke victims.
KW - Adult
KW - Evoked Potentials, Motor
KW - Female
KW - Humans
KW - Male
KW - Manipulation, Chiropractic
KW - Manipulation, Spinal
KW - Motor Cortex/physiology
KW - Motor Neurons/physiology
KW - Muscle Contraction
KW - Muscle, Skeletal/physiology
KW - Transcranial Magnetic Stimulation
UR - http://www.scopus.com/inward/record.url?scp=85048832315&partnerID=8YFLogxK
U2 - 10.1016/j.jelekin.2018.06.010
DO - 10.1016/j.jelekin.2018.06.010
M3 - Journal article
C2 - 29936314
SN - 1050-6411
VL - 42
SP - 24
EP - 35
JO - Journal of Electromyography & Kinesiology
JF - Journal of Electromyography & Kinesiology
ER -