Delirium after fast-track hip and knee arthroplasty – a cohort study of 6331 elderly patients

P. B. Petersen*, C. C. Jørgensen, H. Kehlet, the Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group, Frank Madsen (Medlem af forfattergruppering), Torben B. Hansen (Medlem af forfattergruppering), Henrik Husted (Medlem af forfattergruppering), Mogens B. Laursen (Medlem af forfattergruppering), Lars T. Hansen (Medlem af forfattergruppering), Per Kjærsgaard-Andersen (Medlem af forfattergruppering), Søren Solgaard (Medlem af forfattergruppering)

*Kontaktforfatter

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

38 Citationer (Scopus)

Abstract

Background: Postoperative delirium (PD) is a well-known complication among elderly surgical patients and associated with increased morbidity, mortality and length of stay (LOS). In elective orthopedic surgery, including hip and knee arthroplasty (THA/TKA), most studies report incidences between 5% and 10%. The multimodal optimization of perioperative care (fast-track) aims to enhance recovery and reduce morbidity and LOS, but limited data are available on the effect on PD. Consequently, the study investigated signs of PD associated with LOS > 4 days. Methods: Prospective risk assessment study with retrospective analysis of discharge notes or medical records of signs of PD in 6331 elective primary unilateral THA and TKA patients ≥ 70 years, and LOS > 4 days. Preoperative patient characteristics collected from eight high volume centers with similar standardized fast-track protocols from January 2010 to November 2013. Results: We identified 43 (0.7%) cases of PD symptoms mentioned as a reason for LOS > 4 days among the 789 patients with LOS > 4 days (12.5% of all THA and TKA). PD patients had a mean age of 80.7 [[95% CI] 79.3–82.1] years, being 4.0 [[95% CI] 2.5–5.5] years older compared to patients without PD (P < 0.001). LOS was median 10 [[Q2–Q3] 7–14] days in the PD group vs. 3 [2–3] days in the non-PD group (P < 0.001), without differences in gender or site of arthroplasty (P = 0.139 and 0.499, respectively). Conclusion: Postoperative delirium symptoms contributing to LOS > 4 days in fast-track THA and TKA are rare in elderly patients.

OriginalsprogEngelsk
TidsskriftActa Anaesthesiologica Scandinavica
Vol/bind61
Udgave nummer7
Sider (fra-til)767-772
Antal sider6
ISSN0001-5172
DOI
StatusUdgivet - 2017

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