Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations

Mads T Søndergaard, Yingjie Liu, Malene Brohus, Wenting Guo, Alma Nani, Catherine Carvajal, Michael Fill, Michael T Overgaard, S R Wayne Chen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

OriginalsprogEngelsk
TidsskriftF E B S Journal
ISSN1742-464X
DOI
StatusE-pub ahead of print - 23 jun. 2019

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Ryanodine Receptor Calcium Release Channel
Calmodulin
Mutation
HEK293 Cells
Cardiac Arrhythmias

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title = "Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations",
keywords = "arrhythmia, calmodulin, intracellular Ca release, protein regulation, ryanodine receptor",
author = "S{\o}ndergaard, {Mads T} and Yingjie Liu and Malene Brohus and Wenting Guo and Alma Nani and Catherine Carvajal and Michael Fill and Overgaard, {Michael T} and Chen, {S R Wayne}",
note = "{\circledC} 2019 Federation of European Biochemical Societies.",
year = "2019",
month = "6",
day = "23",
doi = "10.1111/febs.14969",
language = "English",
journal = "F E B S Journal",
issn = "1742-464X",
publisher = "Wiley-Blackwell",

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Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations. / Søndergaard, Mads T; Liu, Yingjie; Brohus, Malene; Guo, Wenting; Nani, Alma; Carvajal, Catherine; Fill, Michael; Overgaard, Michael T; Chen, S R Wayne.

I: F E B S Journal, 23.06.2019.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations

AU - Søndergaard, Mads T

AU - Liu, Yingjie

AU - Brohus, Malene

AU - Guo, Wenting

AU - Nani, Alma

AU - Carvajal, Catherine

AU - Fill, Michael

AU - Overgaard, Michael T

AU - Chen, S R Wayne

N1 - © 2019 Federation of European Biochemical Societies.

PY - 2019/6/23

Y1 - 2019/6/23

KW - arrhythmia

KW - calmodulin

KW - intracellular Ca release

KW - protein regulation

KW - ryanodine receptor

UR - http://www.scopus.com/inward/record.url?scp=85068896113&partnerID=8YFLogxK

U2 - 10.1111/febs.14969

DO - 10.1111/febs.14969

M3 - Journal article

JO - F E B S Journal

JF - F E B S Journal

SN - 1742-464X

ER -