Abstract
Incorporation of a novel pyren-1-ylcarbonyl-functionalized 4′-C-piperazinomethyl-DNA monomer into oligodeoxynucleotides leads to increased thermal stability of duplexes with DNA complements but reduced thermal stability of duplexes with RNA complements. This DNA-selective hybridization is explored for recognition of double-stranded DNA by a novel dual strand invasion approach
Originalsprog | Engelsk |
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Tidsskrift | Chemical Communications |
Vol/bind | 2004 |
Udgave nummer | 9 |
Sider (fra-til) | 1064-1065 |
ISSN | 1359-7345 |
DOI | |
Status | Udgivet - 2004 |
Udgivet eksternt | Ja |