TY - JOUR
T1 - Early signs of autism in toddlers
T2 - A follow-up study in the danish national birth cohort
AU - Lemcke, Sanne
AU - Juul, Svend
AU - Parner, Erik T.
AU - Lauritsen, Marlene B
AU - Thorsen, Poul
PY - 2013/10
Y1 - 2013/10
N2 - To identify possible early signs of autism spectrum disorder (ASD) within the Danish National Birth Cohort, we studied prospectively collected interviews from 76,441 mothers about their children's development and behaviour at 6 and 18 months. In Danish national registries, 720 children with ASD and 231 children with intellectual disability (ID) were identified. At 6 months, associations between early signs and ASD or ID were found only in few areas. At 18 months social, language, and motor skills were delayed, and suspicion of vision and hearing problems were increased for both groups. Signs distinguishing ASD from ID were unclear, and the positive predictive values regarding ASD were below 10 % for individual predictors and aggregated risk scores.
AB - To identify possible early signs of autism spectrum disorder (ASD) within the Danish National Birth Cohort, we studied prospectively collected interviews from 76,441 mothers about their children's development and behaviour at 6 and 18 months. In Danish national registries, 720 children with ASD and 231 children with intellectual disability (ID) were identified. At 6 months, associations between early signs and ASD or ID were found only in few areas. At 18 months social, language, and motor skills were delayed, and suspicion of vision and hearing problems were increased for both groups. Signs distinguishing ASD from ID were unclear, and the positive predictive values regarding ASD were below 10 % for individual predictors and aggregated risk scores.
U2 - 10.1007/s10803-013-1785-z
DO - 10.1007/s10803-013-1785-z
M3 - Journal article
C2 - 23404041
SN - 0162-3257
VL - 43
SP - 2366
EP - 2375
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 10
ER -